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ClinicalTrials.gov public records Last synced Oct 15, 2026, 1:58 PM EDT

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Showing 505–528 of 759 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fire Fighter Fatigue Management Program: Operation Healthy Sleep

NCT01988129
View directory record Official record
Conditions
Shift-Work Sleep Disorder, Insomnia, Restless Leg Syndrome, Obstructive Sleep Apnea, Impaired Driving, Injuries
Interventions
Sleep disorders education and screening
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
1,189 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 16, 2017 · Synced Oct 15, 2026, 1:58 PM EDT
Completed Not applicable Interventional Results available

Continuous Positive Airway Pressure (PAP) Titration and Treatment Versus Auto-adjusting PAP Treatment for Sleep Apnea

NCT00988351
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Continuous positive airway pressure, Auto-adjusting positive airway pressure treatment
Device
Lead sponsor
North Florida Foundation for Research and Education
Other
Eligibility
21 Years to 89 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 3, 2014 · Synced Oct 15, 2026, 1:58 PM EDT
Terminated Phase 4 Interventional Results available

Evaluation of Modafinil vs Placebo for Treatment of Anesthesia Delayed Emergence in Obstructive Sleep Apnea

NCT02494102
View directory record Official record
Conditions
Obstructive Sleep Apnea, Delayed Emergence From Anesthesia
Interventions
Modafinil, Placebo
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 20, 2019 · Synced Oct 15, 2026, 1:58 PM EDT
Recruiting Phase 3 Interventional

AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

NCT07571109
View directory record Official record
Conditions
Obesity, Overweight, Obstructive Sleep Apnoea
Interventions
NNC0487-0111, Placebo (matched to NNC0487-0111)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
20
States / cities
Gilbert, Arizona • Bradenton, Florida • Naples, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 15, 2026, 1:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sleep Apnea in Pregnancy Screening Study

NCT01585844
View directory record Official record
Conditions
Sleep Apnea, Obesity
Interventions
Not listed
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 15, 2026, 1:58 PM EDT
Completed Not applicable Interventional Results available

Trial on Oral Appliance Design for Improving Upper Airway Function and Sleep Quality

NCT03219034
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
oral appliance - A ; washout; oral appliance B, oral appliance - B; washout; oral appliance A
Device
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Oct 15, 2026, 1:58 PM EDT
Completed Phase 3 Interventional Results available

Apnea Positive Pressure Long-Term Efficacy Study

NCT00051363
View directory record Official record
Conditions
Lung Diseases, Sleep Apnea Syndromes, Sleep
Interventions
Active CPAP, Sham CPAP
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
1,105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
5
States / cities
Tucson, Arizona • Palo Alto, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Oct 15, 2026, 1:58 PM EDT
Completed Phase 1 Interventional

Neuromodulation Therapy Device for the Treatment of Sleep Apnea

NCT01117064
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Neuromodulation Therapy Device (NMTD)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 29, 2013 · Synced Oct 15, 2026, 1:58 PM EDT
Recruiting Phase 1 Interventional

Vascular Endothelial Dysfunction in Sleep Apnea

NCT05289063
View directory record Official record
Conditions
Obstructive Sleep Apnea of Adult
Interventions
Atorvastatin 10mg, Placebo, Continuous Positive Airway Pressure Therapy
Drug · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 15, 2026, 1:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Immunological Consequences of Obstructive Sleep Apnea

NCT00214071
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Influenza vaccine
Biological
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 5, 2015 · Synced Oct 15, 2026, 1:58 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Design and Usability Testing of a Tailored Intervention About Sleep and Sleep Disorders Among Transportation Workers

NCT05039528
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Personalized OSA messages, Control
Behavioral · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
Not listed
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 15, 2026, 1:58 PM EDT
Withdrawn No phase listed Observational

Sexual Dysfunction And Hypotestosteronemia In Patients With Obstructive Sleep Apnea Syndrome

NCT00832065
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Sleep Apnea, Hypotestosteronism
Interventions
Not listed
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years to 70 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
2
States / cities
Burlington, Massachusetts • Peabody, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 24, 2017 · Synced Oct 15, 2026, 1:58 PM EDT
Completed Not applicable Interventional Results available

Chronic Care Management With Wearable Devices in Patients Prescribed Positive Airway Pressure Therapy (mPAP) Trial

NCT06039865
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Immediate Intervention, Waitlist control
Behavioral
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 15, 2026, 1:58 PM EDT
Not listed No phase listed Observational

Reiterative Development and Evaluation Study of OSA Therapy System

NCT01634074
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
ApniCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
7
States / cities
Burlingame, California • Redwood City, California • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2013 · Synced Oct 15, 2026, 1:58 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

OSA in Pregnant Women With Chronic HTN

NCT03230110
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Pregnancy, Hypertension
Interventions
WP200U home sleep study device
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Oct 15, 2026, 1:58 PM EDT
Completed Phase 1Phase 2 Interventional

Statins and CPAP in Adipose Tissue of OSA

NCT03308578
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Atorvastatin, Placebo oral capsule
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 16, 2024 · Synced Oct 15, 2026, 1:58 PM EDT
Completed Not applicable Interventional

Study of Effects of Sutures on Results of Palate Surgery for Obstructive Sleep Apnea

NCT00205543
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
uvulopalatopharyngoplasty with or without sutures
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 21, 2012 · Synced Oct 15, 2026, 1:58 PM EDT
Completed No phase listed Observational

Effect of Nasal CPAP on Cardiopulmonary Exercise Testing in Patients With Overlap Syndrome

NCT01033266
View directory record Official record
Conditions
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease
Interventions
CPET
Diagnostic Test
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
2
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 14, 2020 · Synced Oct 15, 2026, 1:58 PM EDT
Completed Phase 3 Interventional

Investigation of a Novel Positive Pressure Therapy to Rescue Patients Failing to Tolerate CPAP During an Initial Encounter

NCT00635206
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
BiPap auto with Fi Flex, Standard CPAP
Device
Lead sponsor
Clayton Sleep Insititute
Industry
Eligibility
21 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 14, 2009 · Synced Oct 15, 2026, 1:58 PM EDT
Not listed Not applicable Interventional

eXciteOSA for Treatment of Mild Obstructive Sleep Apnea

NCT05183009
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
eXciteOSA
Device
Lead sponsor
Signifier Medical Technologies
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
7
States / cities
Birmingham, Alabama • Colorado Springs, Colorado • Lehigh Acres, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2022 · Synced Oct 15, 2026, 1:58 PM EDT
Completed Phase 1Phase 2 Interventional Results available

DAW1033D in Obstructive Sleep Apnea

NCT03383887
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Placebo oral capsule, DAW1033D oral capsule
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 25, 2020 · Synced Oct 15, 2026, 1:58 PM EDT
Completed Phase 3 Interventional Results available

Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder

NCT00078312
View directory record Official record
Conditions
Narcolepsy, Sleep Apnea, Obstructive, Sleep Apnea Syndromes, Shift-Work Sleep Disorder
Interventions
CEP-10953 (Armodafinil)
Drug
Lead sponsor
Cephalon
Industry
Eligibility
18 Years to 65 Years
Enrollment
328 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
41
States / cities
Peoria, Arizona • Phoenix, Arizona • Tucson, Arizona + 35 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2013 · Synced Oct 15, 2026, 1:58 PM EDT
Withdrawn No phase listed Observational

Intraop Ventilation Management and Postop Pulmonary Complications in High Risk Patients for OSA

NCT03135691
View directory record Official record
Conditions
Ventilator-Induced Lung Injury
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Oct 15, 2026, 1:58 PM EDT
Recruiting Not applicable Interventional

Home-based Under Mattress Monitor for OSA

NCT07186725
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSAS), Obstructive Sleep Apnea (SAOS)
Interventions
Under-mattress monitor, level 3 Home Sleep Apnea Test, Mandibular Advancement Device (MAD)
Device
Lead sponsor
Isabel Moreno Hay
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 15, 2026, 1:58 PM EDT