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ClinicalTrials.gov public records Last synced Oct 24, 2026, 4:10 PM EDT

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Showing 313–336 of 3,894 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Older Adult Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

A Study of the Immune Response to Heplisav in Healthy Older Adults

NCT01999699
View directory record Official record
Conditions
Hepatitis B
Interventions
HEPLISAV
Biological
Lead sponsor
Dynavax Technologies Corporation
Industry
Eligibility
50 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Lenexa, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 20, 2019 · Synced Oct 24, 2026, 4:10 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Distal Radius Fracture - Treatment Comparison

NCT01883063
View directory record Official record
Conditions
Minimally Displaced Intra-articular Distal Radius Fracture
Interventions
Surgical Treatment, Non surgical Treatment (Cast or splint)
Device
Lead sponsor
Sonoma Orthopedic Products, Inc.
Industry
Eligibility
65 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
3
States / cities
Winfield, Illinois • Columbia, Missouri • Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Oct 24, 2026, 4:10 PM EDT
Active, not recruiting Not applicable Interventional

A Multidisciplinary Approach to Improve the Health of Older Adults With Blood Cancers After Stem Cell Transplantation

NCT04914338
View directory record Official record
Conditions
Hematopoietic and Lymphoid Cell Neoplasm
Interventions
Health Promotion, Quality-of-Life Assessment, Questionnaire Administration
Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 24, 2026, 4:10 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Milk Protein Feeding After Aerobic Exercise in Older Adults With Pre-diabetes Taking the Biguanide Metformin

NCT02552355
View directory record Official record
Conditions
Physical Activity
Interventions
Metformin, Placebo, Carbohydrate Beverage, Protein Beverage
Drug · Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
55 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 30, 2019 · Synced Oct 24, 2026, 4:10 PM EDT
Recruiting Phase 1Phase 2 Interventional

Cocoa to Maximize Exercise Training in Older Adults - The COMET Trial

NCT07161726
View directory record Official record
Conditions
Mobility Disability
Interventions
(-)-Epicatechin-rich cocoa supplementation combined with exercise training, Placebo combined with exercise training
Combination Product
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 24, 2026, 4:10 PM EDT
Completed Not applicable Interventional

Encouraging Walking in Older Adults

NCT01282944
View directory record Official record
Conditions
Physical Activity
Interventions
Financial Incentive, Peer Network
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
65 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2014 · Synced Oct 24, 2026, 4:10 PM EDT
Recruiting Phase 1Phase 2 Interventional

Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms

NCT06303193
View directory record Official record
Conditions
Myelodysplastic Syndromes
Interventions
pacritinib
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
12 Years to 120 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2035
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 24, 2026, 4:10 PM EDT
Recruiting Phase 4 Interventional

Bone, Exercise, Alendronate, and Caloric Restriction

NCT05764733
View directory record Official record
Conditions
Bone Loss
Interventions
Bisphosphonate, Resistance Training/Bone-Loading Exercise, Placebo
Drug · Behavioral · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
Aurora, Colorado • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 24, 2026, 4:10 PM EDT
Not yet recruiting Not applicable Interventional

Impact of Loss Aversion Messaging and Anticipated Regret for Inaction on Exercise Adherence in Older Adults

NCT07540052
View directory record Official record
Conditions
Mobility Disability, Walking Difficulty
Interventions
Brief Daily At-Home Strength Training Program, Loss Aversion Messaging, Standard Adherence Reminder Messaging
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
65 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 24, 2026, 4:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cerebrospinal Fluid (CSF) Biomarkers Alzheimer's Disease (AD) and Non-AD Dementias

NCT01730430
View directory record Official record
Conditions
Alzheimer's Disease, Dementias
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
55 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2014 · Synced Oct 24, 2026, 4:10 PM EDT
Completed Phase 4 Interventional

Study to Evaluate Safety and Pharmacokinetics of BIVIGAM® in Primary Immune Deficiency Subjects Aged 2 to 16

NCT03164967
View directory record Official record
Conditions
Humoral Immune Response
Interventions
Bivigam
Biological
Lead sponsor
ADMA Biologics, Inc.
Industry
Eligibility
2 Years to 16 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
8
States / cities
Centennial, Colorado • Durham, Florida • North Palm Beach, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Oct 24, 2026, 4:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Video Gaming to Evaluate Front of Pack Labeling With Children

NCT03482336
View directory record Official record
Conditions
Child Obesity
Interventions
Four FOP label designs
Other
Lead sponsor
Michigan State University
Other
Eligibility
6 Years to 10 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Oct 24, 2026, 4:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Flow-Restorative Yoga to Decrease Pain and Inflammation

NCT03790098
View directory record Official record
Conditions
Pain, Inflammation
Interventions
Restorative-Flow Yoga
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 24, 2026, 4:10 PM EDT
Recruiting Not applicable Interventional

bpMedManage: Digital Technology to Support Adherence to Hypertension Medications

NCT06307574
View directory record Official record
Conditions
Aging, Mild Cognitive Impairment, Hypertension
Interventions
bpMedManage
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
60 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Tucson, Arizona • Champaign, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 24, 2026, 4:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Closed-Loop Brain Stimulation as a Potential Intervention for Cognitive Decline

NCT05907343
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer Dementia (AD)
Interventions
Closed-loop TBS, Open-loop TBS
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 90 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 24, 2026, 4:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Balance Control and Recovery in Diabetes Peripheral Neuropathy

NCT06544876
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy, Diabetic Peripheral Neuropathy Type 2, Diabetic Peripheral Neuropathy Type 2 - Uncontrolled, Healthy Aging
Interventions
sit-to-stand, stand to sit, standing perturbation, MRI of sciatic nerve
Behavioral · Other
Lead sponsor
Lisa Griffin
Other
Eligibility
50 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 9, 2024 · Synced Oct 24, 2026, 4:10 PM EDT
Completed Phase 3 Interventional Results available

A Study to Look at Tapentadol Oral Solution in Children and Adolescents in Pain

NCT02081391
View directory record Official record
Conditions
Acute Pain
Interventions
Tapentadol oral solution 4 mg/mL, Tapentadol oral solution 20 mg/mL, Placebo
Drug · Other
Lead sponsor
Grünenthal GmbH
Industry
Eligibility
1 Day to 18 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
13
States / cities
Little Rock, Arkansas • Stanford, California • Miami, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Oct 24, 2026, 4:10 PM EDT
Completed Not applicable Interventional

Dietary Treatments for Cognitive Impairment in Older Adults

NCT02521818
View directory record Official record
Conditions
Mild Cognitive Impairment, Probable Alzheimer's Disease
Interventions
Modified Atkins Diet, NIA Diet for Seniors
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 6, 2019 · Synced Oct 24, 2026, 4:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Elders Preferences in Care Decisions

NCT01575990
View directory record Official record
Conditions
Early Detection of Cancer, Colon Cancer, Decision Making, Patient-Centered Care
Interventions
Making A Decision About CRC Screening, Drivers 65 Plus
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
70 Years to 84 Years
Enrollment
424 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Oct 24, 2026, 4:10 PM EDT
Terminated Phase 3 Interventional Results available

A Study of Prucalopride For Functional Constipation in Children and Teenagers

NCT04759833
View directory record Official record
Conditions
Constipation
Interventions
Prucalopride, Placebo
Drug · Other
Lead sponsor
Takeda
Industry
Eligibility
6 Months to 17 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
41
States / cities
Phoenix, Arizona • Tucson, Arizona • Anaheim, California + 32 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2024 · Synced Oct 24, 2026, 4:10 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Study of the Inhibition of [11C]R-rolipram Binding to Brain Phosphodiesterase - 4 (PDE-4) by HT-0712

NCT01215552
View directory record Official record
Conditions
Healthy Elderly Volunteers
Interventions
HT-0712
Drug
Lead sponsor
Dart NeuroScience, LLC
Industry
Eligibility
55 Years to 80 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Upton, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2011 · Synced Oct 24, 2026, 4:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Watching a Television Show on the Liking of Snack Foods

NCT01694043
View directory record Official record
Conditions
Measure Grams and Kcals of Snack Foods Consumed in Each Condition
Interventions
Healthy Foods, Unhealthy Snack Foods
Other
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years to 30 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 24, 2026, 4:10 PM EDT
Completed Phase 2 Interventional

Mechanisms and Therapeutic Effects of the Relaxation Response in Elderly Hypertensive Patients

NCT00179543
View directory record Official record
Conditions
Hypertension
Interventions
Relaxation response
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
55 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2001
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 19, 2006 · Synced Oct 24, 2026, 4:10 PM EDT
Completed Not applicable Interventional

Esophageal Cancer Multimodal Prehabilitation Study

NCT06027515
View directory record Official record
Conditions
Esophageal Cancer, Esophageal Neoplasms
Interventions
Prehabilitation Program
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
65 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 24, 2026, 4:10 PM EDT