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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Older Adults Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Muscle Lipid and Insulin Resistance in the Elderly

NCT00765505
View directory record Official record
Conditions
Obesity
Interventions
Exercise Group, Health Education Group
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years to 75 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Jun 10, 2026, 6:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bioavailability of Flavonoids and Phenolic Acids From Cranberry Juice Cocktail in Healthy Older Adults

NCT00740077
View directory record Official record
Conditions
Healthy
Interventions
Low calorie, sugar-free cranberry juice cocktail (54% juice)
Other
Lead sponsor
Tufts University
Other
Eligibility
50 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 8, 2009 · Synced Jun 10, 2026, 6:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protein Source on Plasma Amino Acid Concentrations In Older Adults

NCT04243395
View directory record Official record
Conditions
Protein Deposition
Interventions
Pork, Egg, Black beans, Almonds
Other
Lead sponsor
Purdue University
Other
Eligibility
55 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 27, 2022 · Synced Jun 10, 2026, 6:03 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

PK/PD of Oral and Vaporized Delta-9-Tetrahydrocannabinol (THC) in Older Adults

NCT05906511
View directory record Official record
Conditions
Pain, Tolerance, Oral vs Vaporized THC, Abuse Liability
Interventions
Dronabinol 5 MG, Dronabinol 10 MG, 2mg Purified THC in an ethanolic solution, 4mg Purified THC in an ethanolic solution, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Jun 10, 2026, 6:03 AM EDT
Completed Phase 1 Interventional

Study of Clofarabine & Cytosine Arabinoside Therapy for Older Adults With Acute Myeloid Leukemia

NCT00081822
View directory record Official record
Conditions
Acute Myeloid Leukemia
Interventions
clofarabine, Ara-C
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
60 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
3
States / cities
Birmingham, Alabama • Omaha, Nebraska • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 19, 2012 · Synced Jun 10, 2026, 6:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Study of the Effects of Glucose on Cognition in Healthy Young and Elderly People and Parkinson's Disease Patients

NCT00004451
View directory record Official record
Conditions
Parkinson Disease
Interventions
Glucose
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 1998
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 30, 2005 · Synced Jun 10, 2026, 6:03 AM EDT
Completed No phase listed Observational

Delirium in Persons With Dementia

NCT01394328
View directory record Official record
Conditions
Delirium Superimposed on Dementia
Interventions
Not listed
Lead sponsor
Penn State University
Other
Eligibility
65 Years and older
Enrollment
308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 15, 2018 · Synced Jun 10, 2026, 6:03 AM EDT
Not yet recruiting Phase 3 Interventional

A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis

NCT06989567
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
L-citrulline, Placebo
Drug · Other
Lead sponsor
Asklepion Pharmaceuticals, LLC
Industry
Eligibility
6 Years to 21 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Coral Gables, Florida • Atlanta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Jun 10, 2026, 6:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vitamin D Supplementation and Muscle Function in Older Adults

NCT02015611
View directory record Official record
Conditions
Neuromuscular Function
Interventions
Vitamin D, Placebo
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 89 Years
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Jun 10, 2026, 6:03 AM EDT
Completed Not applicable Interventional

Substance Use and Fitness

NCT01305902
View directory record Official record
Conditions
Substance Abuse, Exercise
Interventions
contingency management
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
55 Years to 75 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Jun 10, 2026, 6:03 AM EDT
Terminated Not applicable Interventional Results available

Study of Vosaroxin and Cytarabine for the Treatment of Adults 60 Years of Age or Older With Previously Untreated AML

NCT02485353
View directory record Official record
Conditions
Leukemia, Myeloid, Acute
Interventions
Vosaroxin and Cytarabine
Drug
Lead sponsor
Hamid Sayar
Other
Eligibility
60 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 19, 2017 · Synced Jun 10, 2026, 6:03 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effects Of Detrol LA On Memory And Cognition In Elderly Population

NCT00411437
View directory record Official record
Conditions
Memory, Cognition
Interventions
Tolterodine ER, Oxybutynin ER
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
65 Years to 75 Years
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
9
States / cities
Tucson, Arizona • Brooksville, Florida • DeLand, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Jun 10, 2026, 6:03 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

A Deep Longitudinal Analysis of Next Generation Influenza Vaccines in Older Adults

NCT05518500
View directory record Official record
Conditions
Aging, Influenza Vaccine, Dendritic Cell, Vaccine Response
Interventions
Flu Vaccine (Year 1), Flu Vaccine (Year 2), Flu Vaccine (Year 3), Flu Vaccine (Year 4)
Biological
Lead sponsor
The Jackson Laboratory
Other
Eligibility
65 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jun 10, 2026, 6:03 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Study to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273.214 SARS-CoV-2 (COVID-19) Vaccine in Infants

NCT05584202
View directory record Official record
Conditions
SARS-CoV-2
Interventions
mRNA-1273.214, Placebo
Biological · Other
Lead sponsor
ModernaTX, Inc.
Industry
Eligibility
2 Months to 6 Months
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
39
States / cities
Bessemer, Alabama • Birmingham, Alabama • Tucson, Arizona + 34 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Jun 10, 2026, 6:03 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effects of Triphala and VSL#3 Probiotic Supplementation on Stool Microbiome Profiles and Inflammation

NCT03907501
View directory record Official record
Conditions
Human Microbiome
Interventions
Synbiotic, Probiotic, Placebo
Dietary Supplement
Lead sponsor
University of California, San Diego
Other
Eligibility
65 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Jun 10, 2026, 6:03 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Effect of Weight Loss and Exercise on Liver and Muscle Fat in Obese Elderly

NCT00779207
View directory record Official record
Conditions
Obesity
Interventions
weight loss and exercise, weight loss
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 23, 2008 · Synced Jun 10, 2026, 6:03 AM EDT
Not yet recruiting Not applicable Interventional

Evaluating an Artificial Intelligence-Based Diagnostic Support Tool for Older Adults in Primary Care

NCT07553559
View directory record Official record
Conditions
Diagnostic Support
Interventions
Artificial intelligence-based clinical decision support tool for diagnostic support
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Philadephia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Jun 10, 2026, 6:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Normative Database and Test-Retest Reliability for BrainCheck Assessments

NCT05497427
View directory record Official record
Conditions
Cognitive Change, Cognitive Decline, Cognitive Deterioration, Neurocognitive Deficit
Interventions
BrainCheck Assessment
Device
Lead sponsor
BrainCheck, Inc.
Other
Eligibility
50 Years and older
Enrollment
1,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
5
States / cities
Palo Alto, California • Multiple Locations, Connecticut • Austin, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 1, 2026 · Synced Jun 10, 2026, 6:03 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Study of Inactivated, Split-Virion Influenza Vaccine Compared With Standard Fluzone Vaccine in Elderly Subjects

NCT00388583
View directory record Official record
Conditions
Orthomyxoviridae Infection, Influenza, Myxovirus Infection
Interventions
Split, Inactivated, Trivalent Influenza Vaccine
Biological
Lead sponsor
Sanofi
Industry
Eligibility
65 Years and older
Enrollment
817 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
17
States / cities
Alabaster, Alabama • Tucson, Arizona • Fountain Valley, California + 14 more
Source: ClinicalTrials.gov public record
Updated Apr 17, 2012 · Synced Jun 10, 2026, 6:03 AM EDT
Completed Phase 3 Interventional Results available

AMP002 Phase III Contraceptive Study

NCT03243305
View directory record Official record
Conditions
Contraception
Interventions
AMPHORA
Drug
Lead sponsor
Evofem Inc.
Industry
Eligibility
18 Years to 35 Years · Female only
Enrollment
1,384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
87
States / cities
Mobile, Alabama • Chandler, Arizona • Mesa, Arizona + 67 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Jun 10, 2026, 6:03 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Eltrombopag in Elderly Acute Myelogenous Leukemia (AML)

NCT01113502
View directory record Official record
Conditions
Acute Myelogenous Leukemia (AML)
Interventions
Eltrombopag
Drug
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
60 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Jun 10, 2026, 6:03 AM EDT
Completed Phase 2 Interventional Results available

A Dose-ranging Study of Fluticasone Furoate (FF)

NCT01563029
View directory record Official record
Conditions
Asthma
Interventions
Fluticasone Furoate, Fluticasone Propionate, Placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
5 Years to 11 Years
Enrollment
597 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
37
States / cities
Little Rock, Arkansas • Costa Mesa, California • Huntington Beach, California + 33 more
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Jun 10, 2026, 6:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of SCOUT DS in Subjects With Type 2 Diabetes #2

NCT01346046
View directory record Official record
Conditions
Diabetes Mellitus, Non-Insulin Dependent
Interventions
Not listed
Lead sponsor
VeraLight, Inc.
Industry
Eligibility
18 Years and older
Enrollment
264 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Dec 4, 2012 · Synced Jun 10, 2026, 6:03 AM EDT
Active, not recruiting Phase 2 Interventional

Depressed Mood Improvement Through Nicotine Dosing-3 (Depressed MIND3) Extension

NCT05746546
View directory record Official record
Conditions
Depressive Disorder
Interventions
Transdermal Nicotine patch
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
60 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jun 10, 2026, 6:03 AM EDT