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ClinicalTrials.gov public records Last synced Oct 7, 2026, 10:46 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 3,872 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Older Adults Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Safety, Pharmacokinetics and Pharmacodynamics of Velusetrag in Healthy Elderly Subjects

NCT01467726
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Velusetrag, Placebo
Drug
Lead sponsor
Alfasigma S.p.A.
Industry
Eligibility
65 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Miramar, Florida
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Phase 4 Interventional Results available

A Study to Investigate the Effect of XYWAV on Sleepiness, Polysomnography, and Functional Outcomes in Participants With Idiopathic Hypersomnia or Narcolepsy

NCT05875974
View directory record Official record
Conditions
Idiopathic Hypersomnia, Narcolepsy
Interventions
JZP258 (XYWAV)
Drug
Lead sponsor
Jazz Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
199 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
29
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Irvine, California + 25 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Active Body and Mind Intervention for Older Adults

NCT05233813
View directory record Official record
Conditions
Well Aging
Interventions
Active Body and Mind
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
65 Years and older
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 10, 2022 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Phase 2 Interventional Results available

Use of β-hydroxy-β-methylbutyrate to Counteract Muscle Loss in Men With Prostate Cancer on Androgen Ablation

NCT01607879
View directory record Official record
Conditions
Prostate Cancer
Interventions
Standard of care ADT + (HMB + arginine + glutamine), Standard of care ADT
Drug · Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
60 Years and older · Male only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 22, 2023 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effectiveness of Peer-to-Peer Community Support to Promote Aging in Place

NCT02308696
View directory record Official record
Conditions
Wellness Programs, Hospitalization, Emergency Room
Interventions
Peer-to-Peer Support, Standard Community Services
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
65 Years and older
Enrollment
456 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
5
States / cities
Los Angeles, California • West Palm Beach, Florida • Rochester, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2019 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Phase 3 Interventional Results available

A Study of an Ad26.RSV.preF-based Vaccine and High-dose Seasonal Influenza Vaccine, With and Without Coadministration, in Adults Aged 65 Years and Older

NCT05071313
View directory record Official record
Conditions
Influenza, Human Prevention, Respiratory Syncytial Viruses Prevention
Interventions
Ad26.RSV.preF-based vaccine, Quadrivalent High-dose Influenza Vaccine, Placebo
Biological
Lead sponsor
Janssen Vaccines & Prevention B.V.
Industry
Eligibility
65 Years and older
Enrollment
777 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
19
States / cities
Long Beach, California • Hollywood, Florida • Port Orange, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated May 25, 2025 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Using TMS to Increase Executive Function in Older Adults

NCT02767323
View directory record Official record
Conditions
Aging
Interventions
rTMS, Sham rTMS
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 80 Years
Enrollment
184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 5, 2021 · Synced Oct 7, 2026, 10:46 AM EDT
Active, not recruiting Not applicable Interventional

Voice Activated Personal Assistant for Depression Among Older Adults

NCT06114485
View directory record Official record
Conditions
Depression, Anxiety
Interventions
VIPA Treatment Program, Alexa with Guidebook
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Augmenting Benzodiazepine Receptor Agonist Deprescribing With Acupuncture and Yoga Among Older Adults

NCT06197243
View directory record Official record
Conditions
Anxiety, Insomnia, Benzodiazepine, Deprescription
Interventions
Acupuncture, Yoga, Deprescribing
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
65 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional

Empower@Home:Connected - Feasibility and Preliminary Effect Study

NCT05732740
View directory record Official record
Conditions
Depression, Loneliness, Social Isolation, Depressive Disorder, Mood Disorders, Mental Disorder
Interventions
Empower@Home:Connected
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 2, 2023 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Phase 2 Interventional Results available

Study Of An Investigational Regimen Including FDA Approved HIV Drugs In HIV-Infected Pediatric Subjects

NCT00071760
View directory record Official record
Conditions
Infection, Human Immunodeficiency Virus, HIV Infections
Interventions
GW433908, ritonavir
Drug
Lead sponsor
ViiV Healthcare
Industry
Eligibility
4 Weeks to 2 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2022
U.S. locations
2
States / cities
Jacksonville, Florida • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 10, 2023 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional Results available

Chronic Pain Self-management for Older Adults With Cognitive Impairment: A Randomized Pilot Trial

NCT06182423
View directory record Official record
Conditions
Chronic Pain, Cognitive Impairment
Interventions
STEPS-CI (Support, Training, and Education for Pain Self-management- Cognitively Inclusive version)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 7, 2026, 10:46 AM EDT
Recruiting Not applicable Interventional

A Pilot Randomized Controlled Trial of a Social Network Intervention

NCT07393529
View directory record Official record
Conditions
Advanced Cancer, Older Adults (65 Years and Older), Social Networks
Interventions
SONATA
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
65 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Quantifying the Trainability of Peripheral Nerve Function in Young and Older Adults.

NCT06614556
View directory record Official record
Conditions
Nerve Degeneration, Healthy Aging
Interventions
Resistance Training
Other
Lead sponsor
Oklahoma State University
Other
Eligibility
18 Years to 100 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Community-based Functional Fitness for Adults Aging With Mobility Disability

NCT07283510
View directory record Official record
Conditions
Mobility Disability, Older Adults
Interventions
Functional Fitness
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
60 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 7, 2026, 10:46 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Vitamin D and Marine Omega-3 Fatty Acids on Anemia

NCT01632761
View directory record Official record
Conditions
Anemia
Interventions
Vitamin D3 ., omega-3 fatty acids (fish oil), Vitamin D3 placebo, Fish oil placebo
Dietary Supplement · Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
50 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 7, 2026, 10:46 AM EDT
Recruiting Not applicable Interventional

Empower@Home: Hybrid Effectiveness-Implementation Randomized Controlled Trial (RCT)

NCT06584422
View directory record Official record
Conditions
Depression
Interventions
Empower@Home: An online cognitive-behavioral therapy self-care program for geriatric depression, Telephone friendly visits
Behavioral · Other
Lead sponsor
University of Michigan
Other
Eligibility
50 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peanut Protein Supplementation to Augment Muscle Growth and Improve Markers of Muscle Quality and Health in Older Adults

NCT04015479
View directory record Official record
Conditions
Aging, Sarcopenia
Interventions
Peanut Protein Powder, Full body resistance training
Dietary Supplement · Behavioral
Lead sponsor
Auburn University
Other
Eligibility
50 Years to 80 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Oct 7, 2026, 10:46 AM EDT
Recruiting Not applicable Interventional

Platelet-Rich Fibrinogen in Extraction Socket Healing of the Aged

NCT06943846
View directory record Official record
Conditions
Edentulism
Interventions
Platelet-rich fibrin (PRF)
Procedure
Lead sponsor
University of Nebraska
Other
Eligibility
14 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Foot Self-care in Older Adults

NCT03656341
View directory record Official record
Conditions
Foot
Interventions
2 Feet 4 Life
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
65 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Broken Arrow, Oklahoma • Owasso, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 25, 2019 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Phase 3 Interventional

A Study To Evaluate The Efficacy And Safety Of A Once-Daily Investigational Nasal Spray In Adults And Adolescents With Perennial Allergic Rhinitis (PAR).

NCT00103454
View directory record Official record
Conditions
Rhinitis, Allergic, Perennial
Interventions
GW685698X
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
12 Years and older
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
43
States / cities
Little Rock, Arkansas • Los Angeles, California • Mission Viejo, California + 37 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2016 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Long-term Effects of Blueberry Supplementation on Brain Health in Older Adults

NCT05764824
View directory record Official record
Conditions
Cognitive Decline, Nutrition, Healthy, Brain Injuries
Interventions
Blueberry powder, Controlled and matched powder
Dietary Supplement · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years to 99 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 7, 2026, 10:46 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Neuromodulation Effects in Older Adults

NCT06665022
View directory record Official record
Conditions
Cognitive Impairment, Cognitive Decline
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
University of Florida
Other
Eligibility
60 Years to 95 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Phase 1Phase 2 Interventional

CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Sarcoma

NCT03425279
View directory record Official record
Conditions
Undifferentiated Pleomorphic Sarcoma, Myxofibrosarcoma
Interventions
CAB-AXL-ADC, PD-1 inhibitor
Biological
Lead sponsor
BioAtla, Inc.
Industry
Eligibility
12 Years and older
Enrollment
245 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
35
States / cities
Tucson, Arizona • Los Angeles, California • San Francisco, California + 24 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Oct 7, 2026, 10:46 AM EDT