- Conditions
- Open tíbia Fracture, Osteomyelitis Tibia, Tibial Fractures
- Interventions
- Vancomycin Hydrochloride, Gentamicin, Standard Intramedullary Nail
- Drug · Other
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 497 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 10
- States / cities
- Los Angeles, California • Macon, Georgia • Lexington, Kentucky + 7 more
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- Conditions
- Open tíbia Fracture With Sub-segmental Bone Loss
- Interventions
- Calcium Sulfate, PMMA, No treatment
- Drug · Other
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Open tíbia Fracture
- Interventions
- Antibiotic Cement Bead Pouch, Negative Pressure Wound Therapy
- Drug · Device
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 312 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 29
- States / cities
- Chandler, Arizona • Tucson, Arizona • Davis, California + 24 more