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ClinicalTrials.gov public records Last synced Nov 4, 2026, 7:19 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–45 of 45 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Operative Bleeding Clear all

Conditions: Bloodloss, Surgical Procedures, Operative
Interventions: ecallantide, placebo; Drug
Lead sponsor: Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA); Industry
Eligibility: 18 Years to 85 Years
Enrollment: 276 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 21
States / cities: Birmingham, Alabama • Montgomery, Alabama • Aurora, Colorado + 14 more

Conditions: Sleep-Disordered Breathing, Sleep Apnea Syndromes in Children, Sleep Apnea, Obstructive, Tonsillitis, Tonsillar Hypertrophy, Tonsil Stone, Tonsil Disease
Interventions: Lateral pharyngoplasty, Tonsillectomy; Procedure
Lead sponsor: Loma Linda University; Other
Eligibility: 3 Years to 17 Years
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 4
States / cities: Murrieta, California • Riverside, California • San Bernardino, California

Conditions: Edema, Ecchymosis; Eyelid
Interventions: Tranexamic acid injection, Local anesthetic control; Drug · Other
Lead sponsor: Consultants in Ophthalmic and Facial Plastics Surgery; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 4
States / cities: Southfield, Michigan • The Bronx, New York • Houston, Texas

Conditions: Ecchymosis
Interventions: Arnica montana, Placebo; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years to 89 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Secondary Post Tonsillectomy Hemorrhage, Primary Post Tonsillectomy Hemorrhage
Interventions: Ibuprofen; Drug
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 810 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 3
States / cities: Fort Sam Houston, Texas • Lackland Air Force Base, Texas • Tacoma, Washington

Conditions: Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Pain, Postoperative
Interventions: Tranexamic Acid, Placebo; Drug
Lead sponsor: Dave Bernholt; Other
Eligibility: 14 Years to 25 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 6
States / cities: Skokie, Illinois • St Louis, Missouri • Durham, North Carolina + 3 more

Conditions: Seroma
Interventions: Microporous Polysaccharide Hemospheres (MPH); Device
Lead sponsor: Memorial Health University Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Savannah, Georgia

Conditions: Postpartum Hemorrhage, Pain
Interventions: Procare abdominal binder, Standard of Care; Device · Other
Lead sponsor: Zachary Kuhlmann, DO; Other
Eligibility: 18 Years to 39 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 2
States / cities: Wichita, Kansas

Conditions: Hemorrhage, Surgical, Tonsillar Bleeding
Interventions: Tranexamic Acid Injectable Product, Normal Saline; Drug · Other
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 2 Years to 17 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Operative Hemorrhage
Interventions: Hysterectomy with FloSeal; Procedure
Lead sponsor: David L Zisow MD LLC; Industry
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Randallstown, Maryland

Conditions: Hysterotomy Closure
Interventions: Stratafix synthetic barbed suture; Procedure
Lead sponsor: Evangelical Community Hospital, Lewisburg, PA; Other
Eligibility: 16 Years to 50 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Lewisburg, Pennsylvania

Conditions: Post Operative Blood Loss
Interventions: Tranexamic Acid, Normal Saline Solution; Drug
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years to 80 Years
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: New York, New York

Conditions: Blood Loss, Surgical
Interventions: Arista; Drug
Lead sponsor: Virtua Health, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Marlton, New Jersey

Conditions: Atrial Fibrillation, Stroke, Bleeding
Interventions: Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 3,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 51
States / cities: Little Rock, Arkansas • Los Angeles, California • Stanford, California + 40 more

Conditions: Hemostasis, Bleeding
Interventions: HemoStyp, Surgicel; Device
Lead sponsor: United Health Products, Inc.; Industry
Eligibility: 2 Years and older
Enrollment: 236 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Burbank, California

Conditions: Post-operative Hemorrhage
Interventions: Dexamethasone; Drug
Lead sponsor: Massachusetts Eye and Ear Infirmary; Other
Eligibility: 3 Years to 18 Years
Enrollment: 314 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Bloodloss, Surgical Procedures, Operative
Interventions: Ecallantide, Cyklokapron(R); Drug
Lead sponsor: Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA); Industry
Eligibility: 18 Years to 85 Years
Enrollment: 243 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Surgical Blood Loss, Spinal Surgery
Interventions: SISTER device; Device
Lead sponsor: University of Miami; Other
Eligibility: 22 Years to 99 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Osteoarthritis
Interventions: Peri-articular injection of marcaine/epinephrine, Peri-articular injection of marcaine alone; Procedure
Lead sponsor: Rush University Medical Center; Other
Eligibility: 19 Years to 80 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Acquired Bleeding Disorder, Cardiac Surgery Requiring Cardiopulmonary Bypass
Interventions: activated recombinant human factor VII; Drug
Lead sponsor: Novo Nordisk A/S; Industry
Eligibility: 18 Years and older
Enrollment: 172 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 18
States / cities: Birmingham, Alabama • Tucson, Arizona • San Francisco, California + 14 more

Conditions: Postoperative Ecchymosis
Interventions: DDAVP; Drug
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Lyndhurst, Ohio

Search by objective public record fields.

A Dose-ranging Safety and Efficacy Study of Ecallantide to Reduce Surgical Blood Loss Volume

Lateral Pharyngoplasty Outcomes in Children Undergoing Tonsillectomy

The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery

The Utility of Peri-operative Arnica Montana for Reduction of Ecchymosis in Rhinoplasty Surgery

Safety Study of Post Tonsillectomy Ibuprofen Use in Adults

Extended Post-Operative Oral Tranexamic Acid Dosing After ACL Reconstruction

The Effect of Arista on Post-Operative Bleeding and Wound Drainage Following Mastectomy

Do Elastic Abdominal Binders Reduce Post Operative Pain and Blood Loss?

TranExamic Atomized for Pediatric Post-Operative Tonsillectomy Hemorrhage: Pilot Study

Intrauterine Use of FloSeal: Is it Safe and Useful?

Study to Compare Suture Material in Closure of Uterine Incision in Cesarian Section

Role of Topical Tranexamic Acid in Total Hip Arthroplasty

Arista Hemostatic Powder for Total Knee Post Operative Outcomes Study

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Efficacy and Safety of HemoStyp as an Adjunct for Management of Secondary Hemostasis in the Operative Setting

Evaluating Perioperative Dexamethasone and the Risk of Bleeding in Tonsillectomy

Outcomes and Safety Trial Investigating Ecallantide's Effect on Reducing Surgical Blood Loss Volume in Subjects at High Risk of Bleeding Exposed to Cardio-pulmonary Bypass During Cardiac Surgery

Efficacy of Suction Enabled Retraction Device

Study Comparing Peri-articular Injection of Bupivacaine With and Without Epinephrine

Use of Activated Recombinant Human Factor VII in Cardiac Surgery

DDAVP in the Reduction of Post-operative Ecchymosis in Rhinoplasty