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Showing 1–24 of 62 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Operative Incision Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pre-operative Preparation Using 2% Chlorhexidine Cloth For Shoulder Surgery

NCT01090479
View directory record Official record
Conditions
Post-operative Surgical Site Infections
Interventions
2% Chlorhexidine cloth
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 22, 2023 · Synced Sep 2, 2026, 5:48 PM EDT
Completed No phase listed Observational

Management Practices and the Risk of Infection Following Cardiac Surgery

NCT01089712
View directory record Official record
Conditions
Cardiac Surgery, Infection, Postoperative Wound, Postoperative Wound Infection, Infections, Nosocomial, Management Practices
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
5,158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
9
States / cities
Atlanta, Georgia • Bethesda, Maryland • New York, New York + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2014 · Synced Sep 2, 2026, 5:48 PM EDT
Completed Not applicable Interventional Results available

Negative Pressure Wound Therapy After Cesarean Delivery

NCT01637870
View directory record Official record
Conditions
Major Puerperal Infection, Postpartum, Wound Complications, Wound Seroma, Caesarean Section Wound Separation, Wound Infection
Interventions
Prevena negative pressure wound system
Device
Lead sponsor
Abbey Hardy-Fairbanks
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 17, 2018 · Synced Sep 2, 2026, 5:48 PM EDT
Completed Not applicable Interventional Results available

Prospective Study on Cesarean Wound Outcomes

NCT01697748
View directory record Official record
Conditions
Surgical Site Infection, Cosmetic Appearance of Cesarean Scar, Post Operative Pain
Interventions
Silver-impregnated dressing, Telfa pad dressing
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
660 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
3
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Sep 2, 2026, 5:48 PM EDT
Not yet recruiting Not applicable Interventional

The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery

NCT07145099
View directory record Official record
Conditions
Ventral Hernia, Ventral Incisional Hernia, Post Operative Pain
Interventions
PT Group, Usual Care
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Sep 2, 2026, 5:48 PM EDT
Completed Phase 4 Interventional

Continuous Local Infusion of Anesthetic at the Incisional Site for Scoliosis Surgery

NCT00508066
View directory record Official record
Conditions
Scoliosis
Interventions
Bupivacaine, Normal Saline
Drug
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
8 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 24, 2013 · Synced Sep 2, 2026, 5:48 PM EDT
Completed Not applicable Interventional Results available

Prevena™ Incisional Negative Pressure Wound Therapy in Re-operative Colorectal Surgery

NCT02509260
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Prevena wound management system, Standard wound dressings
Device · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
298 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 13, 2022 · Synced Sep 2, 2026, 5:48 PM EDT
Enrolling by invitation Not applicable Interventional

Comparing the Impact of AMNIOEFFECT Application vs Standard of Care on Post-Operative Healing in Patients Who Have Undergone Thyroid and Parathyroid Surgery Via the Transcutaneous Approach

NCT07173621
View directory record Official record
Conditions
Thyroid; Wound, Parathyroid Diseases, Surgical Incision, Incision
Interventions
Amnioeffect
Other
Lead sponsor
Sarasota Memorial Health Care System
Other
Eligibility
18 Years and older
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Sarasota, Florida
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 2, 2026, 5:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

STRIPES Study: Study To Reduce Infection Post cEsarean Section

NCT02402907
View directory record Official record
Conditions
Chlorhexidine Gluconate Cloths, Infection; Cesarean Section, Infectious Morbidity, Surgical Site Infections, Endometritis
Interventions
2% chlorhexidine gluconate (CHG) cloth, Placebo cloth
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
1,356 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 8, 2020 · Synced Sep 2, 2026, 5:48 PM EDT
Completed Phase 4 Interventional Results available

Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures

NCT02793947
View directory record Official record
Conditions
Pain, Postoperative, Femur Fracture
Interventions
Ropivacaine, Epinephrine, Morphine, 0.9% sodium chloride solution
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Sep 2, 2026, 5:48 PM EDT
Recruiting Phase 3 Interventional

The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal

NCT07142408
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Chlorhexidine gluconate (4%), Mupirocin 2% Ointment
Drug
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
848 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Marlton, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 2, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Post Operative Skin Approximation With Cyanoacrylate Based Wound Closure Adhesives

NCT07613892
View directory record Official record
Conditions
Wound Closure, Dehisced Surgical Wounds
Interventions
Evaluating wound closure products to close larger surgical site incisions, Evaluating wound closure products to close smaller surgical site incisions
Device
Lead sponsor
Medline Industries
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Johnstown, Colorado
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 2, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Impact of Early Post-Operative Water Exposure on Complications of Cutaneous Surgeries

NCT01773694
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Early Water Exposure
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
507 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 31, 2021 · Synced Sep 2, 2026, 5:48 PM EDT
Terminated Phase 2Phase 3 Interventional Results available

Application of Indocyanine Green Angiography for Closed Operative Calcaneus Fractures

NCT01693484
View directory record Official record
Conditions
Fractures, Comminuted, Surgical Wound Dehiscence, Necrosis
Interventions
ICG (Indocyanine Green)
Drug
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Sep 2, 2026, 5:48 PM EDT
Completed Not applicable Interventional Results available

70 vs 110 Degree Side-cut Angles in Femtosecond LASIK

NCT03122535
View directory record Official record
Conditions
Operative Incision
Interventions
FS-LASIK 70 degree side-cut angle, FS-LASIK 110 degree side-cut angle
Device
Lead sponsor
University of Utah
Other
Eligibility
21 Years and older
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated May 27, 2021 · Synced Sep 2, 2026, 5:48 PM EDT
Completed Phase 4 Interventional Results available

Prophylactic Antibiotics for Prevention of Wound Complications Following Vulvectomy

NCT00550290
View directory record Official record
Conditions
Wound Infection
Interventions
Cefazolin PostOperatively, Cefazolin Preoperatively
Drug
Lead sponsor
Aultman Health Foundation
Other
Eligibility
18 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Canton, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 16, 2018 · Synced Sep 2, 2026, 5:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study to Compare Suture Material in Closure of Uterine Incision in Cesarian Section

NCT02517710
View directory record Official record
Conditions
Hysterotomy Closure
Interventions
Stratafix synthetic barbed suture
Procedure
Lead sponsor
Evangelical Community Hospital, Lewisburg, PA
Other
Eligibility
16 Years to 50 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Lewisburg, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 9, 2018 · Synced Sep 2, 2026, 5:48 PM EDT
Completed Phase 2 Interventional Results available

Effect of Exeporfinium Chloride (XF-73) Gel on Nasal S.Aureus in Patients at Risk of Post-op Staphylococcal Infection

NCT03915470
View directory record Official record
Conditions
Staphylococcal Infections, Surgical Site Infection
Interventions
XF-73, Placebo
Drug
Lead sponsor
Destiny Pharma Plc
Industry
Eligibility
18 Years to 75 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
7
States / cities
Gainesville, Florida • Pocatello, Idaho • Des Moines, Iowa + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2023 · Synced Sep 2, 2026, 5:48 PM EDT
Not listed Phase 4 Interventional

Study on the Reapplication of Chloraprep After Lower Extremity Surgery and Prior to Dressing Application

NCT02017145
View directory record Official record
Conditions
Lower Extremity Surgery, Surgical Site Infection, Bacterial Colonization, Surgical Antiseptic
Interventions
Chloraprep
Drug
Lead sponsor
Sanford Health
Other
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Feb 18, 2014 · Synced Sep 2, 2026, 5:48 PM EDT
Terminated Phase 1Phase 2 Interventional

A Phase I/II Double-Blind, Randomized, Controlled Study to Evaluate the Safety and Efficacy of RUT058-60

NCT02280395
View directory record Official record
Conditions
Postoperative Wound Infection-deep, Post Operative Wound Infection
Interventions
RUT058-60, Sterile saline for irrigation
Drug
Lead sponsor
Pulmatrix Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
4
States / cities
Mobile, Alabama • La Jolla, California • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Sep 2, 2026, 5:48 PM EDT
Completed Not applicable Interventional Results available

De-Implementation of Unnecessary Surgical Antibiotic Prophylaxis in Children

NCT04366440
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Order set review and modification with facilitation, Order set review and modification
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
0 Days to 75 Years
Enrollment
18,267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
10
States / cities
St. Petersburg, Florida • Boston, Massachusetts • Ann Arbor, Michigan + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 2, 2026, 5:48 PM EDT
Active, not recruiting Phase 4 Interventional

PVI to Prevent S. Aureus SSI After Fixation of HELEF (POTENT Study)

NCT05763602
View directory record Official record
Conditions
Surgical Site Infection
Interventions
povidone-iodine topical ointment
Drug
Lead sponsor
Loreen Herwaldt
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
6
States / cities
Atlanta, Georgia • Indianapolis, Indiana • Iowa City, Iowa + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 2, 2026, 5:48 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of Local Anesthetic at Incision Site

NCT02483689
View directory record Official record
Conditions
Post Operative Pain, Appendicitis
Interventions
Pre Incisional Local Anesthetic, Pre-Incisional Saline, Post-Closure Local Anesthetic, Post-Closure Saline
Drug · Other
Lead sponsor
Valley Anesthesiology Consultants
Other
Eligibility
9 Years to 17 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Sep 2, 2026, 5:48 PM EDT
Completed Phase 4 Interventional Results available

Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)

NCT03261830
View directory record Official record
Conditions
Supracondylar Humerus Fracture, Post Operative Wound Infection
Interventions
Cefazolin, Clindamycin, Saline
Drug
Lead sponsor
Sumit Gupta
Other
Eligibility
Up to 13 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Sep 2, 2026, 5:48 PM EDT