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ClinicalTrials.gov public records Last synced Oct 18, 2026, 5:01 AM EDT

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Showing 217–240 of 663 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Operative Wound Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Perfusion Assessment of Wound Closure Techniques in Primary Total Knee Arthroplasty

NCT01924403
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Staple Closure, Vertical Mattress Closure, Running Subcuticular Closure
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 16, 2015 · Synced Oct 18, 2026, 5:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Detection of Staph Colonization in Pre-op Arthroplasty Patients

NCT01648088
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Oct 18, 2026, 5:01 AM EDT
Recruiting Phase 2 Interventional

Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis

NCT02422641
View directory record Official record
Conditions
Metastatic Breast Cancer, Leptomeningeal Disease
Interventions
High-dose Methotrexate (8 gm/m2; HD-MTX)
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2027
U.S. locations
3
States / cities
Baltimore, Maryland • St Louis, Missouri • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 18, 2026, 5:01 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Trial Comparing the Optimal Timing of Antibiotic Prophylaxis at the Time of Cesarean Delivery

NCT00811603
View directory record Official record
Conditions
Cesarean Section, Infection
Interventions
Cefazolin (Timing of Antibiotic Prophylaxis)
Drug
Lead sponsor
MemorialCare
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
2
States / cities
Long Beach, California • Orange, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2009 · Synced Oct 18, 2026, 5:01 AM EDT
Withdrawn No phase listed Observational

Operative Versus Non-Operative Treatment of Clavicle Fracture in PolyTrauma

NCT01133769
View directory record Official record
Conditions
Clavicle Fracture, Chest Injury
Interventions
Not listed
Lead sponsor
Anna Rockich
Other
Eligibility
18 Years to 79 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 20, 2017 · Synced Oct 18, 2026, 5:01 AM EDT
Completed Not applicable Interventional Results available

Study Looking at the Effect of Silverlon on Post Operative Wound Infections

NCT01143883
View directory record Official record
Conditions
Infections, Surgery
Interventions
Silverlon, Standard of Care Dressing
Other
Lead sponsor
Jorge Marcet
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 13, 2013 · Synced Oct 18, 2026, 5:01 AM EDT
Completed No phase listed Observational Results available

Topical Antibiotic Treatment for Spine Surgical Site Infection

NCT02776774
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Oct 18, 2026, 5:01 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

A Comparison of Two Pain Control Techniques on Deliruim in Hip Fracture Patients

NCT01547468
View directory record Official record
Conditions
Hip Fracture
Interventions
Femoral Nerve Catheterization, Intravenous Opioids
Procedure
Lead sponsor
Leslie Thomas
Other
Eligibility
50 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2022
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 18, 2026, 5:01 AM EDT
Completed Phase 3 Interventional Results available

Effect of rFVIIa on Peri-operative Blood Loss in Patients Undergoing Major Burn

NCT00243243
View directory record Official record
Conditions
Burns
Interventions
Recombinant Factor VIIa, Placebo
Drug
Lead sponsor
United States Army Institute of Surgical Research
Federal
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced Oct 18, 2026, 5:01 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Immobilization of Postoperative Distal Radius Fractures

NCT02802774
View directory record Official record
Conditions
Distal Radius Fractures
Interventions
Plaster Splint, Velcro Brace, Soft Dressing
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
2
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Oct 18, 2026, 5:01 AM EDT
Completed Phase 4 Interventional Results available

Prevention of Surgical Site Infections: Effectiveness of Nasal Povidone-Iodine and Nasal Mupirocin

NCT01313182
View directory record Official record
Conditions
Surgical Site Infection
Interventions
mupirocin calcium ointment, 2%, 3M Skin and Nasal Antiseptic
Drug
Lead sponsor
Solventum US LLC
Industry
Eligibility
18 Years and older
Enrollment
1,874 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 2, 2024 · Synced Oct 18, 2026, 5:01 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Vacuum Assisted Closure for Cesarean Section

NCT02390401
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Vacuum-assisted closure, Standard sterile dressing
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
166 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
4
States / cities
Lebanon, New Hampshire • Nashua, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 22, 2018 · Synced Oct 18, 2026, 5:01 AM EDT
Recruiting Phase 3 Interventional

Diluted Aqueous Povidone-Iodine Compared to Saline to Decrease Surgical Site Infections

NCT06363877
View directory record Official record
Conditions
Surgical Site Infection
Interventions
Povidone-Iodine, Normal Saline
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 80 Years
Enrollment
1,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Oct 18, 2026, 5:01 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections

NCT01431339
View directory record Official record
Conditions
Abscess, Wound Infection, Surgical Site Infection, Cellulitis
Interventions
IV Dalbavancin, Vancomycin/Linezolid
Drug
Lead sponsor
Durata Therapeutics Inc., an affiliate of Allergan plc
Industry
Eligibility
18 Years to 85 Years
Enrollment
739 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
30
States / cities
Montgomery, Alabama • Anaheim, California • Buena Park, California + 26 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2014 · Synced Oct 18, 2026, 5:01 AM EDT
Completed Not applicable Interventional Results available

Prevention of Neurosurgical Wound Infections

NCT00915967
View directory record Official record
Conditions
Surgical Wound Infections
Interventions
Vancomycin, Placebo (Saline Solution)
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 99 Years
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 30, 2019 · Synced Oct 18, 2026, 5:01 AM EDT
Completed Phase 3 Interventional Results available

Liposomal Bupivacaine With Bupivacaine in Ankle Fracture Open Reduction Internal Fixation (ORIF)

NCT02480621
View directory record Official record
Conditions
Ankle Fracture
Interventions
Liposomal Bupivacaine with Bupivacaine
Drug
Lead sponsor
Jamaica Hospital Medical Center
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Jamaica, New York
Source: ClinicalTrials.gov public record
Updated Oct 20, 2017 · Synced Oct 18, 2026, 5:01 AM EDT
Completed Phase 1Phase 2 Interventional Results available

DFA-02 in Patients Undergoing Colorectal Surgery

NCT01496352
View directory record Official record
Conditions
Surgical Site Infection
Interventions
DFA-02, Placebo
Drug
Lead sponsor
Dr. Reddy's Laboratories Limited
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
5
States / cities
Florence, Alabama • Tampa, Florida • Columbus, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2014 · Synced Oct 18, 2026, 5:01 AM EDT
Completed No phase listed Observational

Patient-Specific Precision Injury Signatures in Multiply Injured Orthopaedic Patients

NCT03772730
View directory record Official record
Conditions
Pelvic, Acetabular, Femur, or Diaphyseal Tibial Operative Orthopaedic Injuries
Interventions
Not listed
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 55 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
8
States / cities
Miami, Florida • Indianapolis, Indiana • Lexington, Kentucky + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2023 · Synced Oct 18, 2026, 5:01 AM EDT
Completed No phase listed Observational

Surgical Treatment of Adult Trigger Finger

NCT02196233
View directory record Official record
Conditions
Trigger Finger
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 95 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Oct 18, 2026, 5:01 AM EDT
Recruiting Phase 1 Interventional

A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections

NCT07379684
View directory record Official record
Conditions
Surgical Wound Infection, Traumatic Wound Infection
Interventions
Amicidin-β topical solution - 15 mL, Amicidin-β topical solution - 50 mL, Standard of Care (SOC)
Drug
Lead sponsor
Macro Biologics, Inc.
Industry
Eligibility
18 Years to 79 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
5
States / cities
Torrance, California • Idaho Falls, Idaho • Baltimore, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 18, 2026, 5:01 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Evaluation of Breast Reduction Techniques

NCT04509037
View directory record Official record
Conditions
Breast Reductions
Interventions
Not listed
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 18, 2026, 5:01 AM EDT
Terminated Not applicable Interventional

Comminuted Intra-Articular Distal Tibia Fracture Fixation Using Computer Techniques

NCT02845245
View directory record Official record
Conditions
Tibial Fractures
Interventions
3D printed plastic model prototype, 3D CT scan, Plain film radiographs
Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Oct 18, 2026, 5:01 AM EDT
Withdrawn Not applicable Interventional

Single Incision Versus Standard Laparoscopic Splenectomy

NCT01276561
View directory record Official record
Conditions
Hereditary Spherocytosis, Idiopathic Thrombocytopenic Purpura
Interventions
Single Incision Splenectomy, Laparoscopic Splenectomy
Procedure
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
1 Year to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 3, 2017 · Synced Oct 18, 2026, 5:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Comparison of Monosyn and Monocryl Sutures in Surgical Wounds

NCT00731913
View directory record Official record
Conditions
Wounds
Interventions
Absorable, monofilament sutures: Monosyn and Monocryl
Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2015 · Synced Oct 18, 2026, 5:01 AM EDT