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ClinicalTrials.gov public records Last synced Nov 6, 2026, 4:45 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 489 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Ophthalmic Surgery Clear all

Conditions: Cataracts, Inflammation
Interventions: Difluprednate ophthalmic emulsion, 0.05%, Prednisolone acetate ophthalmic suspension, 1.0%; Drug
Lead sponsor: Alcon Research; Industry
Eligibility: Up to 3 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Glaucoma
Interventions: Triamcinolone injection, sub-tenon; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 2
States / cities: San Jose, California • Stanford, California

Conditions: Ophthalmic Surgery
Interventions: Zymar; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Stanford, California

Conditions: Inflammation, Pain, Cataract
Interventions: Loteprednol Etabonate Gel (BID), Loteprednol Etabonate Gel (TID), Vehicle (BID), Vehicle (TID); Drug
Lead sponsor: Bausch & Lomb Incorporated; Industry
Eligibility: 18 Years and older
Enrollment: 514 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Bridgewater, New Jersey

Conditions: Glaucoma, Glaucoma, Open Angle
Interventions: SOLX Titanium Sapphire Laser (TiSaLT), Argon Laser Trabeculoplasty (ALT); Device
Lead sponsor: SOLX, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2009
U.S. locations: 5
States / cities: Petaluma, California • Tampa, Florida • New York, New York + 2 more

Conditions: Mixed Astigmatism
Interventions: MEL 80 Mixed Astigmatism Treatment; Device
Lead sponsor: Carl Zeiss Meditec, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 126 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 5
States / cities: San Diego, California • Greenwood Village, Colorado • Kansas City, Missouri + 2 more

Conditions: Inflammation, Pain, Cataract
Interventions: Mapracorat, Vehicle; Drug
Lead sponsor: Bausch & Lomb Incorporated; Industry
Eligibility: 18 Years and older
Enrollment: 177 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Development of Ptosis After Vitreo-retinal Surgery
Interventions: Not listed
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Cataract
Interventions: MICOR-304; Device
Lead sponsor: Carl Zeiss Meditec, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 3
States / cities: Vestavia Hills, Alabama • Cape Coral, Florida • Bloomington, Minnesota

Conditions: Glaucoma, Open-Angle
Interventions: OMNI® Surgical System; Device
Lead sponsor: Sight Sciences, Inc.; Industry
Eligibility: Not listed
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 10
States / cities: Atlanta, Georgia • Wichita, Kansas • Bloomington, Minnesota + 7 more

Conditions: Cataract, Astigmatism
Interventions: Normal Toric IOL implantation with digital marking; Diagnostic Test
Lead sponsor: Colvard Kandavel Eye Center; Other
Eligibility: 50 Years to 90 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 2
States / cities: Encino, California

Conditions: Glaucoma
Interventions: 5-fluorouracil, Mitomycin C; Drug
Lead sponsor: Indiana University; Other
Eligibility: Not listed
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 2
States / cities: Indianapolis, Indiana

Conditions: Ocular Inflammation and Pain After Cataract Surgery
Interventions: APP13007, 0.05%, APP13007, 0.1%, APP13007 Placebo, 0.05%, APP13007 Placebo, 0.1%; Drug
Lead sponsor: Formosa Pharmaceuticals, Inc.; Industry
Eligibility: 50 Years and older
Enrollment: 165 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 9
States / cities: Phoenix, Arizona • Inglewood, California • Rancho Cordova, California + 5 more

Conditions: Cataract Extraction
Interventions: Cataract surgery with Perfect Capsule and Sodium Chloride; Procedure
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 4 Years to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Cataract
Interventions: Clobetasol Propionate, Vehicle; Drug
Lead sponsor: Salvat; Industry
Eligibility: 18 Years and older
Enrollment: 215 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 18
States / cities: Sun City, Arizona • Hemet, California • Inglewood, California + 15 more

Conditions: Postoperative Complications, Cataract
Interventions: Bromfenac, Placebo; Drug
Lead sponsor: Bausch & Lomb Incorporated; Industry
Eligibility: 18 Years and older
Enrollment: 527 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 39
States / cities: Birmingham, Alabama • Little Rock, Arkansas • Irvine, California + 34 more

Conditions: Glaucoma, Open-Angle
Interventions: Xen Gel Stent; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: Not listed
Enrollment: 137 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Primary Open Angle Glaucoma, Primary Angle Closure Glaucoma, Pseudoexfoliation Glaucoma, Pigmentary Glaucoma, Traumatic Glaucoma, Uveitic Glaucoma, Neovascular Glaucoma
Interventions: Molteno 3 glaucoma drainage shunt; Procedure
Lead sponsor: Wills Eye; Other
Eligibility: 19 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Ocular Hypertension
Interventions: Not listed
Lead sponsor: United States Naval Medical Center, San Diego; Federal
Eligibility: 18 Years and older · Male only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: San Diego, California

Conditions: Geographic Atrophy
Interventions: OpRegen; Biological
Lead sponsor: Genentech, Inc.; Industry
Eligibility: 50 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2031
U.S. locations: 15
States / cities: Beverly Hills, California • Sacramento, California • San Francisco, California + 12 more

Conditions: Pseudophakia, Inflammation
Interventions: loteprednol 0.5% ophthalmic solution; Drug
Lead sponsor: Toyos Clinic; Other
Eligibility: 18 Years and older
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Independence, Missouri

Conditions: Cataract Surgery, Cataract
Interventions: Apple Vision Pro (Head-Mounted Spatial Computing Display), Zeiss Artevo Digital Surgical Microscope; Device
Lead sponsor: Sharp HealthCare; Other
Eligibility: 18 Years and older
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: San Diego, California

Conditions: Intraocular Melanoma, Melanoma (Skin)
Interventions: incomplete Freund's adjuvant, multi-epitope melanoma peptide vaccine, sargramostim; Biological
Lead sponsor: University of Virginia; Other
Eligibility: 12 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2002
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Open-Angle Glaucoma
Interventions: iStent plus Cataract Surgery, Cataract surgery only; Device · Procedure
Lead sponsor: Glaukos Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 31
States / cities: Beverly Hills, California • Petaluma, California • Sacramento, California + 27 more

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Difluprednate Pediatric Study for the Treatment of Inflammation Post-Cataract Surgery

Post-Operative Sub-Tenon Kenalog in Glaucoma Filtering Surgery

One Hour Preoperative Gatifloxacin

Loteprednol Ophthalmic Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery

SOLX Titanium Sapphire Laser for Trabeculoplasty

Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Mixed Astigmatism

Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation Following Cataract Surgery

Preoperative and Intraoperative Factors Related to the Development of Ptosis After Retinal Surgery

Assessment of Low Energy Lens Fragmentation Cataract Extraction in Patients Undergoing Cataract Surgery

An Observational Multicenter Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System In Pseudophakic Eyes With Primary Open Angle Glaucoma (ORION 2.0)

Refractive Accuracy of Toric Intraocular Lens Implantation Using Digital Marking Compared to Conventional Marking

Outcomes of Intraoperative 5-Fluorouracil Versus Mitomycin C

A Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of APP13007 to Treat Inflammation and Pain After Cataract Surgery

Clinical Evaluation of the Use of Sealed Capsule Irrigation With Sodium Chloride During Pediatric Cataract Surgery and IOL Implantation

Clobetasol Propionate Ophthalmic Nanoemulsion 0.05% for the Treatment of Inflammation and Pain Associated With Cataract Surgery (CLOSE-2)

Safety and Efficacy Study of Topical Bromfenac Versus Placebo to Treat Ocular Inflammation After Cataract Surgery

Retrospective Review of Xen Gel Stent Implantation With Open vs. Closed Conjunctiva Approach

Patch Graft Material Safety and Effectiveness in Covering Glaucoma Drainage Device Tube

Intraocular Pressure During Robotic Assisted Laparoscopic Procedures Utilizing Steep Trendelenburg Positioning

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

Clinical Outcomes and Evaluation of Lotemax 0.5% in Treatment of Ocular Inflammation Associated With Cataract Surgery

Evaluation of Head-Mounted Spatial Computing and Three-Dimensional (3D) Visualization in Ocular Microsurgery: A Safety and Workflow Study

Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By Surgery

A Study of the Trabecular Micro-bypass Stent in Combination With Cataract Surgery in Subjects With Open Angle Glaucoma