Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.

Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 28, 2026, 11:12 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1345–1368 of 1,481 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Opioid Related Disorders Clear all
Completed Phase 2 Interventional

Comparison of Buprenorphine and Methadone - 3

NCT00000334
View directory record Official record
Conditions
Opioid-Related Disorders
Interventions
Buprenorphine
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
23 Years to 45 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Oct 28, 2026, 11:12 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Efficacy of Extended Release Tramadol for Treating Prescription Opioid Withdrawal

NCT00980044
View directory record Official record
Conditions
Substance Withdrawal Syndrome
Interventions
Tramadol, Placebo
Drug
Lead sponsor
Michelle Lofwall
Other
Eligibility
18 Years to 55 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Oct 28, 2026, 11:12 PM EDT
Completed Not applicable Interventional

Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2

NCT00249457
View directory record Official record
Conditions
Behavior, Addictive, Cocaine Abuse, Cocaine Dependence, Heroin Dependence, Opioid Dependence
Interventions
Contingency management
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2006
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 30, 2017 · Synced Oct 28, 2026, 11:12 PM EDT
Completed No phase listed Observational

Optimizing CAB-LA as PrEP for Women Who Inject Drugs

NCT05799339
View directory record Official record
Conditions
HIV Infections, Opioid Use, Trauma, Psychological
Interventions
Not listed
Lead sponsor
Alexis Roth
Other
Eligibility
18 Years and older · Female only
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Oct 28, 2026, 11:12 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Management of Postoperative Pain After Cesarean Delivery Using Bridge Auricular Percutaneous Nerve Field Stimulator

NCT06434714
View directory record Official record
Conditions
Post-operative Pain, Acute, Cesarean Section, Opioid Use Disorder, Opioids; Harmful Use
Interventions
Auricular percutaneous nerve field stimulator, Sham auricular percutaneous nerve field stimulator
Device
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years to 55 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Oct 28, 2026, 11:12 PM EDT
Completed No phase listed Observational

Emergency Department Connection to Care With Buprenorphine for Opioid Use Disorder

NCT03544112
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Employ a multifaceted approach to facilitate clinical protocol implementation, Initiate BUP (SL-BUP or XR-BUP) in the ED
Behavioral · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
4
States / cities
Claremont, New Hampshire • Manchester, New Hampshire • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 30, 2019 · Synced Oct 28, 2026, 11:12 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Pioglitazone to Treat Opioid Withdrawal Symptoms

NCT01517165
View directory record Official record
Conditions
Opioid-Related Disorders
Interventions
Pioglitazone, Placebo
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Oct 28, 2026, 11:12 PM EDT
Recruiting Not applicable Interventional

Real-time Opioid Study

NCT07768007
View directory record Official record
Conditions
Substance Use Disorder (SUD)
Interventions
real-time functional magnetic resonance imaging (rt-fMRI) neurofeedback
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 28, 2026, 11:12 PM EDT
Enrolling by invitation Not applicable Interventional

PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R33 Phase Clinical Trial)

NCT07886944
View directory record Official record
Conditions
Burnout, Secondary Trauma, Compassion Fatigue, Opioid Use Disorder, Stimulant Use Disorder, Substance Use Disorder
Interventions
PATH (Peer Advanced Training for total Health)
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 27, 2026 · Synced Oct 28, 2026, 11:12 PM EDT
Completed Not applicable Interventional Results available

PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Opioid-Naive Population

NCT04601493
View directory record Official record
Conditions
Opioid-use Disorder, Opioid Use, Opioid Abuse
Interventions
Choice Architecture Nudge, PMP Integration & Nudge
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
Not listed
Enrollment
631 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Oct 28, 2026, 11:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Mass Media Photographs on Drug-Related Stigma

NCT06743178
View directory record Official record
Conditions
Opioid Use Disorder, Substance Use Disorders, Stigma, Social
Interventions
Photo of a person injecting drugs, Photo of EMS responding to an overdose (White), Photo of EMS responding to an overdose (Black), Photo of a person receiving treatment (Jail), Photo of a person receiving treatment (Community), Photo of a person in recovery (White), Photo of a person in recovery (Black), Photo of a family member of an overdose decedent
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
3,570 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Oct 28, 2026, 11:12 PM EDT
Not yet recruiting Phase 2 Interventional

Targeting Treatment-Resistant OUD With Ketamine-Assisted Mindfulness Oriented Recovery Enhancement

NCT07369089
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Ketamine, Mindfulness-Oriented Recovery Enhancement (MORE), Support Group
Drug · Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
La Jolla, California • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 28, 2026, 11:12 PM EDT
Not listed Phase 1Phase 2 Interventional

Community Reinforcement and Family Training for Drug Abuse Treatment Retention/HIV Risk Reduction

NCT00609089
View directory record Official record
Conditions
Heroin Dependence, Opiate Dependence, Substance Dependence
Interventions
CRAFT-T, Treatment as usual
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 14, 2012 · Synced Oct 28, 2026, 11:12 PM EDT
Not listed Early Phase 1 Interventional

Digital Support Intervention for Pregnant People with Opioid Use Disorders

NCT06652880
View directory record Official record
Conditions
Digital Intervention, Bibliotherapy
Interventions
Digital technology, Bibliotherapy
Device · Other
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Oct 28, 2026, 11:12 PM EDT
Completed No phase listed Observational

Technology for MAT in Primary Care - Phase 1

NCT05006846
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Opioid Addiction Recovery Support Software Platform
Other
Lead sponsor
Q2i, LLC
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2021 · Synced Oct 28, 2026, 11:12 PM EDT
Completed Phase 2 Interventional Results available

Cannabidiol in the Treatment of Opioid Use Disorder

NCT06206291
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Placebo, Cannabidiol (CBD) 200mg, Cannabidiol (CBD) 400mg
Drug
Lead sponsor
Yasmin Hurd
Other
Eligibility
18 Years to 65 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 28, 2026, 11:12 PM EDT
Recruiting Not applicable Interventional

VA Transitional Pain Service Study

NCT06223503
View directory record Official record
Conditions
Chronic Opioid Use
Interventions
Transitional Pain Service
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 28, 2026, 11:12 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Opioid Use Disorder and Pain

NCT06800703
View directory record Official record
Conditions
Opioid Use Disorder, Healthy Controls Group - Age and Sex-matched
Interventions
follow up interviews for 12 months to determine opioid use
Behavioral
Lead sponsor
Yale University
Other
Eligibility
21 Years to 60 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 28, 2026, 11:12 PM EDT
Not listed Phase 2 Interventional

Computerized Chemosensory-Based Orbitofrontal Cortex (CBOT) for Opioid Use Disorder

NCT04850664
View directory record Official record
Conditions
Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe, Withdrawal Symptoms, Craving, Negative Affectivity
Interventions
CBOT + TAU, Sham + TAU
Drug
Lead sponsor
Evon Medics LLC
Industry
Eligibility
18 Years to 70 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 6, 2021 · Synced Oct 28, 2026, 11:12 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Pilot Study to Evaluate Skin Swabbing With Chlorhexidine to Prevent Skin And Soft Tissue Infections Among People Who Inject Drugs

NCT06733506
View directory record Official record
Conditions
Opioid Use Disorder, Injection Drug Use, Skin and Soft Tissue Infections (SSTIs)
Interventions
Chlorhexidine gluconate, Isopropyl Alcohol 70% Topical Application Solution, Skin Prep Before Injecting Recreational/Street Drugs
Drug · Behavioral
Lead sponsor
Gabriel John Culbert
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 28, 2026, 11:12 PM EDT
Completed Not applicable Interventional Results available

Incentives to Decrease Opioid Use - Pilot

NCT04235582
View directory record Official record
Conditions
Substance-Related Disorders, Opioid-Related Disorders, Behavior Therapy
Interventions
App + Inputs Contingency Management, App + Outcomes Contingency Management
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
3
States / cities
Berkeley, California • Chicago, Illinois • Wauwatosa, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 28, 2026, 11:12 PM EDT
Withdrawn No phase listed Observational

Validation of a Pediatric-Specific Abstinence Syndrome Assessment Tool

NCT00792415
View directory record Official record
Conditions
Substance Withdrawal Syndrome
Interventions
Not listed
Lead sponsor
Banner Health
Other
Eligibility
2 Weeks to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Mesa, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Oct 28, 2026, 11:12 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study to Test the Safety and Efficacy of Cannabidiol as a Treatment Intervention for Opioid Relapse

NCT01311778
View directory record Official record
Conditions
Opiate Addiction
Interventions
Cannabidiol, Fentanyl
Drug
Lead sponsor
Hurd,Yasmin, Ph.D.
Individual
Eligibility
21 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 22, 2013 · Synced Oct 28, 2026, 11:12 PM EDT
Recruiting Phase 3 Interventional

Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3

NCT05834478
View directory record Official record
Conditions
Withdrawal Symptoms, Opioid Use Disorder, Opioid Use
Interventions
Transcutaneous Cervical Vagal Nerve Stimulation, Sham Stimulation, [F-18]Fallypride
Device · Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 75 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
6
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 28, 2026, 11:12 PM EDT