Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 6, 2026, 4:32 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 86 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Organ Failure Clear all

Conditions: Brain Death, Heart Failure
Interventions: Thyroxine, Saline; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 14 Years to 55 Years
Enrollment: 838 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 14
States / cities: Phoenix, Arizona • San Diego, California • Denver, Colorado + 11 more

Conditions: Transplant;Failure,Kidney, Transplant; Failure, Liver, Transplant; Failure, Bowel, Abdominal Wall Defect, Abdominal Wall Fistula, Abdominal Wall Hernia, Abdominal Wall Injury
Interventions: Abdominal Wall Transplant with another solid organ transplant, Abdominal Wall Transplant alone; Procedure
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2028
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Kidney Transplantation
Interventions: Arm 1: SOC (mTOR + CNI), Arm 2A: TRACT/MONO mTOR, Arm 2B: TRACT/MONO CNI; Drug · Biological
Lead sponsor: Singulera Therapeutics Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2031
U.S. locations: 3
States / cities: Phoenix, Arizona • Chicago, Illinois • Rochester, Minnesota

Conditions: Trauma, Burns, Multiple Organ Failure
Interventions: Not listed
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: Not listed
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2018
U.S. locations: 4
States / cities: Maywood, Illinois • Dallas, Texas • Galveston, Texas + 1 more

Conditions: Malignant Neoplasm, Unspecified Adult Solid Tumor, Protocol Specific
Interventions: imatinib mesylate, laboratory biomarker analysis, pharmacological study; Drug · Other
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 16 Years and older
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2001
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Severe Hepatic Veno-Occlusive Disease
Interventions: Defibrotide; Drug
Lead sponsor: Jazz Pharmaceuticals; Industry
Eligibility: Not listed
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2015
U.S. locations: 22
States / cities: Duarte, California • Palo Alto, California • Denver, Colorado + 19 more

Conditions: End Stage Liver DIsease, Liver Failure
Interventions: VitaSmart™Liver Machine Perfusion System, Static cold storage; Device · Other
Lead sponsor: Bridge to Life Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 228 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 15
States / cities: San Bernadino, California • San Francisco, California • Stanford, California + 12 more

Conditions: Extracorporeal Membrane Oxygenation, Red Blood Cell Transfusion, Organ Failure, Multiple
Interventions: Red blood cell transfusion; Other
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 0 Days to 6 Years
Enrollment: 228 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 20
States / cities: Phoenix, Arizona • Little Rock, Arkansas • Los Angeles, California + 17 more

Conditions: Sepsis, Severe Sepsis, End Organ Damage, Multi Organ Failure
Interventions: vitamin D3, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 80 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Cardiovascular Disease, Acute Rejection of Cardiac Transplant, Cardiac Transplant Rejection, Heart Transplant Failure and Rejection
Interventions: Blood Draw of up to 10 ml; Diagnostic Test
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: Not listed
Enrollment: 540 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 8
States / cities: Little Rock, Arkansas • Atlanta, Georgia • Chicago, Illinois + 4 more

Conditions: Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasms, Pulmonary Disease, Chronic Obstructive, Heart Failure, Congestive, Liver Cirrhosis, Kidney Failure, Chronic, Lung Diseases, Interstitial, Peripheral Vascular Disease, Diabetes With End Organ Injury
Interventions: Survey-based Patient/Clinician Jumpstart, EHR-based Clinician Jumpstart; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 756 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 3
States / cities: Seattle, Washington

Conditions: Multiple Organ Failure
Interventions: CoQ10, Placebo; Dietary Supplement
Lead sponsor: American Burn Association; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Galveston, Texas

Conditions: Septic Shock, Thrombocytopenia, Multiple Organ Failure
Interventions: Not listed
Lead sponsor: Children's Healthcare of Atlanta; Other
Eligibility: 6 Months to 18 Years
Enrollment: 86 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2012
U.S. locations: 12
States / cities: Washington D.C., District of Columbia • Atlanta, Georgia • Iowa City, Iowa + 9 more

Conditions: Heart Failure, Chronic Kidney Disease, End-stage Kidney Disease
Interventions: Planned delayed implantation of kidney allograft with ex vivo machine perfusion kidney preservation.; Other
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2035
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Acute Respiratory Failure
Interventions: arterial blood gas; Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 646 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Trauma; Complications, Multiple Organ Failure
Interventions: Traumatized population, Healthy Volunteers; Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2019
U.S. locations: 2
States / cities: Gainesville, Florida • Seattle, Washington

Conditions: Kidney Transplantation
Interventions: Not listed
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 4 Years and older
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2014
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Kidney Injury, Kidney Failure, Kidney Failure, Chronic, Kidney Failure, Acute, Kidney Diseases, Kidney Transplant Rejection, Kidney Transplant Infection, Kidney Transplant; Complications, Kidney Disease, Chronic, Kidney Ischemia
Interventions: AlloSure, PAXGene; Diagnostic Test
Lead sponsor: George Washington University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Trauma, Burns, Multiple Organ Failure
Interventions: Not listed
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 16 Years and older
Enrollment: 610 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2018
U.S. locations: 4
States / cities: Denver, Colorado • Pittsburgh, Pennsylvania • Dallas, Texas + 1 more

Conditions: Pelvic Organ Prolapse
Interventions: Not listed
Lead sponsor: Atlantic Health System; Other
Eligibility: Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Morristown, New Jersey

Conditions: Kidney Failure, Kidney Transplant, Deceased Donor Kidney Transplant
Interventions: Not listed
Lead sponsor: Paris Translational Research Center for Organ Transplantation; Other
Eligibility: Not listed
Enrollment: 300,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive, Heart Failure, Congestive, Liver Cirrhosis, Kidney Failure, Chronic, Multiple Organ Failure, Health Care Quality, Access, and Evaluation, Intensive Care Units, Palliative Care, Health Services, Palliative Care, Patient Care, Lung Diseases, Cerebrovascular Disorders, Brain Injuries
Interventions: Facilitator-Based Intervention; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 977 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 3
States / cities: Seattle, Washington

Conditions: Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive, Heart Failure，Congestive, Liver Cirrhosis, Kidney Failure, Chronic, Lung Diseases, Interstitial, Peripheral Vascular Disease, Diabetes With End Organ Injury
Interventions: EHR-based Clinician Jumpstart; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 2,512 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 3
States / cities: Seattle, Washington

Conditions: Sepsis, Severe Sepsis
Interventions: Intravenous fluid; Drug
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 18 Years and older
Enrollment: 142 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 5
States / cities: Newark, Delaware • Boston, Massachusetts • Detroit, Michigan + 2 more

Search by objective public record fields.

Intravenous Thyroxine for Heart-Eligible Organ Donors

Abdominal Wall Transplant

REgulatory T Cell Therapy to Achieve Immunosuppression REduction

Inflammation and the Host Response to Injury (Burns)

Imatinib Mesylate in Treating Patients With Advanced Cancer and Kidney Failure

Defibrotide for the Treatment of Severe Hepatic Veno-Occlusive Disease in Hematopoetic Stem Cell Transplant Patients

Bridge to HOPE: Hypothermic Oxygenated Perfusion Versus Cold Storage Prior to Liver Transplantation

Trial of Indication-Based Transfusion of Red Blood Cells in ECMO

Vitamin D Status in Patients With Severe Sepsis

Quantitative Detection of Circulating Donor-Specific DNA in Organ Transplant Recipients (DTRT-Multi-Center Study)

Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)

Efficacy of Coenzyme Q10 Supplementation on Multi-Organ Dysfunction in Severely Burned Patients

Patient Plasma Response and Outcome in Septic Shock With Thrombocytopenia Associated Multiple Organ Failure in Children

Staged Kidney Transplantation During Combined Heart/Kidney Transplantation

Imputation of PaO2 From SaO2

A Validation of a Genomics Based Prognostic in Severe Trauma

The Role of Connective Tissue Growth Factor in the Development of Kidney Disease After Organ Transplantation

Personalization of Immunosuppressive Treatment for Organ Transplant Recipients

Inflammation and the Host Response to Injury (Trauma)

Do Patients With Early Post Operative Recurrence of Pelvic Organ Prolapse Have a Genetic Predisposition?

Worldwide Assessment of Deceased Donor Kidney Utilization

Facilitating Communication Study

Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1)

Preemptive Resuscitation for Eradication of Septic Shock