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ClinicalTrials.gov public records Last synced Jul 22, 2026, 2:11 AM EDT

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Showing 1–17 of 17 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Osseointegration Clear all
Terminated No phase listed Observational

Sinus Augmentation With Dental Implant

NCT00991393
View directory record Official record
Conditions
Maxillary Sinus Bone Loss
Interventions
INFUSE® Bone Graft
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
5
States / cities
Fullerton, California • Denver, North Carolina • Philadelphia, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2012 · Synced Jul 22, 2026, 2:11 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Five Year Survival Study Evaluating the Genesis Dental Implant System

NCT01573026
View directory record Official record
Conditions
Dental Implants
Interventions
Not listed
Lead sponsor
Keystone Dental, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
8
States / cities
Newport Beach, California • Woodland Hills, California • Oakbrook Terrace, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2012 · Synced Jul 22, 2026, 2:11 AM EDT
Recruiting Not applicable Interventional

Transtibial Osseointegration

NCT06636136
View directory record Official record
Conditions
Amputation; Traumatic, Leg, Lower
Interventions
OPRA
Device
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
22 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
Bethesda, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Jul 22, 2026, 2:11 AM EDT
Recruiting No phase listed Observational

Microbiome Population Adaptation Study

NCT06310239
View directory record Official record
Conditions
Amputation With Osseointegration
Interventions
Collection of biologic samples and data
Other
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Jul 22, 2026, 2:11 AM EDT
Active, not recruiting Not applicable Interventional

Transfemoral Osseointegrated Prosthesis Limb-Load Symmetry Training

NCT05695911
View directory record Official record
Conditions
Amputation, Transfemoral Amputation, Osseointegration
Interventions
Limb Load Biofeedback Training Intervention, Attention Control
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Jul 22, 2026, 2:11 AM EDT
Not listed Not applicable Interventional

Osseointegrated Transtibial Prosthesis With Neural Interface

NCT05249049
View directory record Official record
Conditions
Amputation
Interventions
e-OPRA Implant System for Transtibial Amputees
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
22 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 20, 2022 · Synced Jul 22, 2026, 2:11 AM EDT
Terminated No phase listed Observational

Localized Alveolar Ridge Augmentation With Space Maintenance Devices

NCT00991432
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
INFUSE® Bone Graft
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
8
States / cities
Los Angeles, California • Greenwood Village, Colorado • Sarasota, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2012 · Synced Jul 22, 2026, 2:11 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of a Powered Ankle Prosthesis Capable of Bidirectional Control Via Neural Recording and Cutaneous Stimulation in Free-Space and Walking Tasks

NCT07645729
View directory record Official record
Conditions
Amputation
Interventions
Powered Prosthesis, Prescribed Prosthesis
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Jul 22, 2026, 2:11 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Cortical Shield for Facial Bone Reconstruction

NCT04827693
View directory record Official record
Conditions
Tooth Loss, Tooth Diseases, Tooth Fracture, Tooth Injuries, Periodontal Bone Loss, Periodontitis, Peri-Implantitis, Tooth Decay
Interventions
Not listed
Lead sponsor
Verdugo, Fernando, DDS
Individual
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Jul 22, 2026, 2:11 AM EDT
Active, not recruiting Not applicable Interventional

Magnetic Bead Tracking System and eOPRA Implant System With Bionic Prosthesis for Transtibial Amputees

NCT06391697
View directory record Official record
Conditions
Amputation
Interventions
eOPRA Implant System for Transtibial Amputees and Magnetic Bead Tracking System
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
22 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 22, 2026, 2:11 AM EDT
Completed Not applicable Interventional

e-OPRA Implant System for Lower Limb Amputees

NCT03720171
View directory record Official record
Conditions
Amputation
Interventions
e-OPRA Implant System
Device
Lead sponsor
Integrum
Industry
Eligibility
22 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Jul 22, 2026, 2:11 AM EDT
Completed No phase listed Observational

Alveolar Bone Changes in Diabetes (ABCD) Study

NCT02395315
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Well-controlled diabetic (WC), Poorly controlled diabetics (PC)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 85 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
3
States / cities
Minneapolis, Minnesota • Houston, Texas • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 1, 2022 · Synced Jul 22, 2026, 2:11 AM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

EFS Functional Expectations of Transhumeral Percutaneous OI Patients

NCT03824444
View directory record Official record
Conditions
Transhumeral Amputation
Interventions
PODS
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 25, 2024 · Synced Jul 22, 2026, 2:11 AM EDT
Not yet recruiting Not applicable Interventional

Intraosseous Antibiotics for Osseointegration

NCT07621094
View directory record Official record
Conditions
Osseointegration Infection
Interventions
intraosseous antibiotic delivery
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
5
States / cities
Aurora, Colorado • New York, New York • Charlotte, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 22, 2026, 2:11 AM EDT
Recruiting Phase 1 Interventional

Influence of Prosthetic Foot Stiffness on Transtibial Osseointegrated Bone-Anchored Limb Outcomes

NCT07263945
View directory record Official record
Conditions
Amputation, Transtibial Amputation - Unilateral, Bone Anchored Devices, Osseointegration
Interventions
As-prescribed prosthetic foot stiffness, A prosthetic foot that is two prosthetic foot stiffness categories stiffer than the stiffness of the as-prescribed prosthetic foot, A prosthetic foot that is two prosthetic foot stiffness categories softer than the stiffness of the as-prescribed prosthetic foot
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Jul 22, 2026, 2:11 AM EDT
Terminated No phase listed Observational

Localized Alveolar Ridge Augmentation With Dental Implant

NCT00991965
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
INFUSE® Bone Graft
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
6
States / cities
Loma Linda, California • Los Angeles, California • Sarasota, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2012 · Synced Jul 22, 2026, 2:11 AM EDT
Recruiting Not applicable Interventional

Powered Prosthesis for Use With TF Osseointegration Recipients

NCT06160882
View directory record Official record
Conditions
Amputation
Interventions
Powered Prosthesis Training and EMG data collection, Perform Osseointegration (OI) surgery and Targeted Muscle Reinnervation (TMR)
Other · Procedure
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Jul 22, 2026, 2:11 AM EDT