- Conditions
- Osteo Arthritis Shoulders, Osteonecrosis, Rotator Cuff Tears, Rotator Cuff Tear Arthropathy, Ankylosing Spondylitis, Post-traumatic Osteoarthritis, Rheumatoid Arthritis, Fracture, Infections
- Interventions
- Not listed
- Lead sponsor
- Exactech
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 20,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2031
- U.S. locations
- 24
- States / cities
- Laguna Woods, California • Redwood City, California • Stockton, California + 20 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 134
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Osteoarthritis, Pain
- Interventions
- Placebo, Fulranumab 1 mg, Fulranumab 3 mg, Opioid
- Drug
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 79 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 36
- States / cities
- Birmingham, Alabama • Huntsville, Alabama • Cerritos, California + 33 more
- Conditions
- Osteo Arthritis Knee, Total Knee Replacement
- Interventions
- Total Knee Arthroplasty using LEGION™ Total Knee System
- Procedure
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 128 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2020
- U.S. locations
- 5
- States / cities
- Vero Beach, Florida • Des Moines, Iowa • Louisville, Kentucky + 2 more
- Conditions
- Osteoarthritis, Arthritis, Rheumatoid, Avascular Necrosis of Bone, Post-traumatic Arthritis, Rheumatoid Arthritis
- Interventions
- Total knee replacement
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 399 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2006
- U.S. locations
- 4
- States / cities
- La Jolla, California • Crystal River, Florida • Melbourne, Florida + 1 more
- Conditions
- Degenerative Joint Disease
- Interventions
- Iconacy Hip System
- Device
- Lead sponsor
- Iconacy Orthopedic Implants, LLC.
- Industry
- Eligibility
- 30 Years to 80 Years
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2019
- U.S. locations
- 2
- States / cities
- Louisville, Kentucky
- Conditions
- Osteoarthritis
- Interventions
- Liposuction with Local Anesthesia, Intra articular infusion of AD-SVF
- Procedure · Biological
- Lead sponsor
- Ageless Regenerative Institute
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Aventura, Florida
- Conditions
- Osteoarthritis, Post-traumatic Arthritis
- Interventions
- ATTUNE TKA with ATTUNE RUI, ATTUNE TKA with ATTUNE SUI
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 88 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 2
- States / cities
- La Jolla, California • Wilkes-Barre, Pennsylvania
- Conditions
- Knee Osteoarthritis
- Interventions
- CRx-102 (2.7/90), Prednisolone, Placebo, CRx-102 (2.7/180), CRx-102 (2.7/360)
- Drug
- Lead sponsor
- Zalicus
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 279 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 57
- States / cities
- Huntsville, Alabama • Chandler, Arizona • Mesa, Arizona + 54 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- Cingal, Triamcinolone Hexacetonide (TH), Placebo
- Drug
- Lead sponsor
- Anika Therapeutics, Inc.
- Industry
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 231 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 26
- States / cities
- Chandler, Arizona • Tucson, Arizona • Anaheim, California + 21 more
- Conditions
- Arthroplasty, Replacement, Hip
- Interventions
- Accolade® TMZF® Hip Stem
- Device
- Lead sponsor
- Stryker Orthopaedics
- Industry
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 241 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2014
- U.S. locations
- 11
- States / cities
- Newport Beach, California • San Diego, California • Boynton Beach, Florida + 8 more
- Conditions
- Osteoarthritis
- Interventions
- Buprenorphine transdermal delivery system
- Drug
- Lead sponsor
- Purdue Pharma LP
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 225 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1996 – 1999
- U.S. locations
- 10
- States / cities
- Huntsville, Alabama • Phoenix, Arizona • Westminster, Colorado + 6 more
- Conditions
- Osteoarthritis, Osteo Arthritis Knee, Osteo Arthritis Shoulders, Osteoarthritis of Multiple Joints, Osteoarthritis, Hip, Osteoarthritis - Ankle/Foot
- Interventions
- Tissue Stromal Vascular Fraction (tSVF) Arm 1, PRP Concentrate Arm 1, Tissue Stromal Vascular Fraction (tSVF) Arm 2, PRP Concentrate Arm 2, Cellular Stromal Vascular Fraction (cSVF) Arm 2, Cellular Stromal Vascular Fraction (cSVF) Arm 3, Sterile Normal Saline (IV Solution)
- Procedure · Biological · Drug
- Lead sponsor
- Healeon Medical Inc
- Industry
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2027
- U.S. locations
- 2
- States / cities
- Valencia, California • Stevensville, Montana
- Conditions
- Osteoarthritis
- Interventions
- CR845 0.25 mg, CR845 0.50 mg, CR845 1 mg, CR845 5 mg
- Drug
- Lead sponsor
- Cara Therapeutics, Inc.
- Industry
- Eligibility
- 25 Years and older
- Enrollment
- 81 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 5
- States / cities
- Omaha, Nebraska • Las Vegas, Nevada • Greensboro, North Carolina + 2 more
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip
- Interventions
- REGN475, Placebo
- Drug
- Lead sponsor
- Regeneron Pharmaceuticals
- Industry
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 421 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 72
- States / cities
- Birmingham, Alabama • Mobile, Alabama • Chandler, Arizona + 69 more
- Conditions
- Osteoarthritis
- Interventions
- AGG-523 (Aggrecanase Inhibitor)
- Drug
- Lead sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
- Industry
- Eligibility
- 55 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 5
- States / cities
- Boston, Massachusetts • Newton, Massachusetts • Winchester, Massachusetts + 1 more
- Conditions
- NSAID-induced Gastroduodenal Injury, Ulcers, Rheumatoid Arthritis, Osteoarthritis
- Interventions
- Cobiprostone, Placebo, Non-steroidal anti-inflammatory drug
- Drug
- Lead sponsor
- Sucampo Pharma Americas, LLC
- Industry
- Eligibility
- 40 Years to 70 Years
- Enrollment
- 121 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 19
- States / cities
- Phoenix, Arizona • Chula Vista, California • Loma Linda, California + 16 more
- Conditions
- Osteoarthritis, Arthritis, Avascular Necrosis, Fracture of the Femoral Neck or Head, Congenital Hip Dysplasia
- Interventions
- Mpact Acetabular Shell
- Device
- Lead sponsor
- Medacta International SA
- Industry
- Eligibility
- Not listed
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2022
- U.S. locations
- 4
- States / cities
- Denver, Colorado • Boise, Idaho • Libertyville, Illinois + 1 more
- Conditions
- Osteoarthritis of the Knee
- Interventions
- 4 mL injection of Ampion, 4 mL Injection of Placebo
- Biological · Drug
- Lead sponsor
- Ampio Pharmaceuticals. Inc.
- Industry
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 342 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Englewood, Colorado
- Conditions
- Osteoarthritis
- Interventions
- Cementless Total Knee Arthroplasty
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 540 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2027
- U.S. locations
- 10
- States / cities
- Denver, Colorado • DeLand, Florida • Lebanon, New Hampshire + 7 more
- Conditions
- Osteoarthritis, Pain
- Interventions
- Placebo, Fulranumab 1 mg, Fulranumab 3 mg
- Drug
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 41 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 7
- States / cities
- El Cajon, California • Sherman Oaks, California • Miami, Florida + 4 more
- Conditions
- Osteoarthritis, Hip, Avascular Necrosis of Hip
- Interventions
- One of the following hip implants may be used within this arm of the study: G7 Acetabular System, Taperloc Complete System, Avenir and Avenir Complete Systems, and Echo Bi-Metric System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 2
- States / cities
- Jacksonville, Florida • Saint Joseph, Missouri
- Conditions
- Osteoarthritis Knee
- Interventions
- Gel-One, PBS
- Device
- Lead sponsor
- Seikagaku Corporation
- Industry
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 814 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 41
- States / cities
- Birmingham, Alabama • Sheffield, Alabama • Phoenix, Arizona + 38 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- Amniotic Fluid, Saline Placebo
- Other
- Lead sponsor
- MiMedx Group, Inc.
- Industry
- Eligibility
- 30 Years and older
- Enrollment
- 156 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 4
- States / cities
- Birmingham, Alabama • Atlanta, Georgia • Des Plaines, Illinois + 1 more
- Conditions
- Osteoarthritis of the Knee
- Interventions
- NKTR-181, Placebo
- Drug
- Lead sponsor
- Nektar Therapeutics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 296 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 34
- States / cities
- Mobile, Alabama • Tucson, Arizona • Garden Grove, California + 29 more