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ClinicalTrials.gov public records Last synced Oct 15, 2026, 4:23 AM EDT

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Showing 721–744 of 2,314 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Otolaryngologic Disease Clear all
Completed Phase 2 Interventional

Resistance Training During Radiation Therapy for Pharyngeal or Laryngeal Cancer

NCT00827164
View directory record Official record
Conditions
Head and Neck Cancer, Pharyngeal Cancer, Laryngeal Cancer
Interventions
Nutrition Counseling, Resistance Training
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 90 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Oct 15, 2026, 4:23 AM EDT
Completed Phase 1Phase 2 Interventional

OTO-413 in Subjects With Speech-in-Noise Hearing Impairment

NCT04129775
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
OTO-413, Placebo
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
21 Years to 64 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
8
States / cities
Colorado Springs, Colorado • Hollywood, Florida • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2022 · Synced Oct 15, 2026, 4:23 AM EDT
Completed Not applicable Interventional

Efficacy & Safety of Submucosal Endoscopic Myotomy With Mucosal Flap (SEMF) in the Treatment of Patients With Achalasia

NCT01438398
View directory record Official record
Conditions
Achalasia, Dysphagia
Interventions
Submucosal endoscopic myotomy with mucosal flap technique, Submucosal Endoscopic Mucosal Flap (SEMF) technique
Procedure
Lead sponsor
Winthrop University Hospital
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2017 · Synced Oct 15, 2026, 4:23 AM EDT
Recruiting Phase 3 Interventional

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

NCT06589804
View directory record Official record
Conditions
Metastatic Head and Neck Squamous Cell Carcinoma, Metastatic Hypopharyngeal Squamous Cell Carcinoma, Metastatic Laryngeal Squamous Cell Carcinoma, Metastatic Oral Cavity Squamous Cell Carcinoma, Metastatic Oropharyngeal Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma, Recurrent Laryngeal Squamous Cell Carcinoma, Recurrent Neck Squamous Cell Carcinoma of Unknown Primary, Recurrent Oral Cavity Squamous Cell Carcinoma, Recurrent Oropharyngeal Squamous Cell Carcinoma, Refractory Head and Neck Squamous Cell Carcinoma, Refractory Hypopharyngeal Squamous Cell Carcinoma, Refractory Laryngeal Squamous Cell Carcinoma, Refractory Oral Cavity Squamous Cell Carcinoma, Refractory Oropharyngeal Squamous Cell Carcinoma, Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8, Stage IV Hypopharyngeal Carcinoma AJCC v8, Stage IV Laryngeal Cancer AJCC v8, Stage IV Lip and Oral Cavity Cancer AJCC v8, Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Interventions
Biospecimen Collection, Cetuximab, Computed Tomography, Magnetic Resonance Imaging, Pembrolizumab, Positron Emission Tomography
Procedure · Biological
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
200
States / cities
Little Rock, Arkansas • Marysville, California • Palo Alto, California + 161 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 15, 2026, 4:23 AM EDT
Completed Phase 3 Interventional Results available

Once-Daily Investigational Nasal Spray In Adults And Adolescents With Perennial Allergic Rhinitis (PAR)

NCT00289198
View directory record Official record
Conditions
Rhinitis, Allergic, Perennial
Interventions
FF, Placebo
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
12 Years and older
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
8
States / cities
San Diego, California • Baltimore, Maryland • Wheaton, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2018 · Synced Oct 15, 2026, 4:23 AM EDT
Completed No phase listed Observational

Nasal and Peripheral Blood Biomarkers of CRS Patients Before and After Surgical Intervention

NCT03250429
View directory record Official record
Conditions
Sinusitis, Chronic
Interventions
Sinus surgery
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 15, 2026, 4:23 AM EDT
Completed Early Phase 1 Interventional Results available

Study of a Topical Nasal Spray to Ease the Symptoms of Hayfever

NCT01500629
View directory record Official record
Conditions
Rhinitis, Allergic, Seasonal
Interventions
C-1266-7, C-1266-6 (placebo)
Device
Lead sponsor
McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 27, 2017 · Synced Oct 15, 2026, 4:23 AM EDT
Completed Phase 2 Interventional Results available

SPI-1005 for the Treatment of Patients With Meniere's Disease

NCT03325790
View directory record Official record
Conditions
Meniere's Disease
Interventions
200mg SPI-1005 BID, 400mg SPI-1005 BID, Placebo
Drug · Other
Lead sponsor
Sound Pharmaceuticals, Incorporated
Industry
Eligibility
18 Years to 75 Years
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
13
States / cities
Fresno, California • San Diego, California • San Francisco, California + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2023 · Synced Oct 15, 2026, 4:23 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Assessing the Efficacy of a Serotonin and Norepinephrine Reuptake Inhibitor for Improving Meniere's Disease Outcomes

NCT04218123
View directory record Official record
Conditions
Meniere Disease
Interventions
Venlafaxine, Placebo oral tablet
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Oct 15, 2026, 4:23 AM EDT
Completed Phase 3 Interventional Results available

12-Month OL Intranasal Fluticasone Propionate BID Using OptiNose Device

NCT01623310
View directory record Official record
Conditions
Nasal Polyps
Interventions
Fluticasone Propionate
Drug
Lead sponsor
Optinose US Inc.
Industry
Eligibility
18 Years and older
Enrollment
223 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
16
States / cities
Birmingham, Alabama • Brandon, Florida • Normal, Illinois + 13 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Oct 15, 2026, 4:23 AM EDT
Completed Phase 3 Interventional

A Study To Evaluate The Efficacy And Safety Of A Once-Daily Investigational Nasal Spray In Adults And Adolescents With Perennial Allergic Rhinitis (PAR).

NCT00103454
View directory record Official record
Conditions
Rhinitis, Allergic, Perennial
Interventions
GW685698X
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
12 Years and older
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
43
States / cities
Little Rock, Arkansas • Los Angeles, California • Mission Viejo, California + 37 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2016 · Synced Oct 15, 2026, 4:23 AM EDT
Terminated Not applicable Interventional Results available

Propel Stent vs Kenalog-soaked Nasopore After Frontal Drill-out

NCT03534362
View directory record Official record
Conditions
Stent, Sinusitis, Frontal
Interventions
Nasopore, Propel
Device
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 90 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 21, 2020 · Synced Oct 15, 2026, 4:23 AM EDT
Withdrawn Not applicable Interventional

Sparing Parotid Ducts Via MRI Sialography for Reduced Patient Reported Xerostomia

NCT06276946
View directory record Official record
Conditions
Oropharynx Cancer, Head and Neck Cancer, Xerostomia
Interventions
standard radiotherapy, experimental radiotherapy
Radiation
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 5, 2025 · Synced Oct 15, 2026, 4:23 AM EDT
Not listed Not applicable Interventional

Lyric4 Outcomes Evaluation

NCT06169683
View directory record Official record
Conditions
Hearing Loss
Interventions
Lyric4
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Fremont, California • Cary, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 13, 2023 · Synced Oct 15, 2026, 4:23 AM EDT
Completed No phase listed Observational

Effectiveness of Beclomethasone Dipropionate Nasal Aerosol for Perennial Allergic Rhinitis

NCT01632540
View directory record Official record
Conditions
Perennial Allergic Rhinitis (PAR)
Interventions
Beclomethasone Dipropionate (BDP) Nasal Aerosol
Drug
Lead sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Industry
Eligibility
12 Years and older
Enrollment
824 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
46
States / cities
Little Rock, Alaska • Phoenix, Arizona • Encinitas, California + 39 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2014 · Synced Oct 15, 2026, 4:23 AM EDT
Terminated Not applicable Interventional Results available

Effect of the Erchonia® HLS™ for the Relief of Tinnitus Symptoms

NCT05091060
View directory record Official record
Conditions
Tinnitus
Interventions
Erchonia HLS
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Walnut Creek, California
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Oct 15, 2026, 4:23 AM EDT
Active, not recruiting Not applicable Interventional

Safety and Effectiveness of Cochlear Implantation in an Expanded Adult Population

NCT06293482
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Interventions
Cochlear™ Nucleus® System
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
9
States / cities
Phoenix, Arizona • Tucson, Arizona • Santa Monica, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 15, 2026, 4:23 AM EDT
Completed Phase 2Phase 3 Interventional Results available

An Exploratory Study of PQ Grass 27600 SU

NCT04687059
View directory record Official record
Conditions
Rhinitis, Allergic, Seasonal
Interventions
PQ Grass, Active Placebo, Standard Placebo
Biological · Drug
Lead sponsor
Allergy Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
8
States / cities
Lexington, Kentucky • White Marsh, Maryland • Ocean Township, New Jersey + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 15, 2026, 4:23 AM EDT
Completed No phase listed Observational

Clinical Performance of the Checkable Medical At-Home Strep A Test

NCT05107362
View directory record Official record
Conditions
Streptococcus Pyogenes Infection, Pharyngitis, Respiratory Tract Infections
Interventions
untrained lay user performs investigational diagnostic test
Diagnostic Test
Lead sponsor
Checkable Medical Inc
Industry
Eligibility
5 Years and older
Enrollment
1,347 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
22
States / cities
Beverly Hills, California • Jacksonville, Florida • Miami, Florida + 18 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Oct 15, 2026, 4:23 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Microassay and Allergy Skin Prick Test Correlation Study

NCT03514303
View directory record Official record
Conditions
Allergy Pollen
Interventions
Spiriplex Allergenex Microassay
Diagnostic Test
Lead sponsor
United Allergy Services
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Oct 15, 2026, 4:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

North Carolina Newborn Exome Sequencing for Universal Screening

NCT02826694
View directory record Official record
Conditions
Metabolism, Inborn Errors, Hearing Loss, Hereditary Disease
Interventions
Well infant, whole exome sequencing, Diagnosed, whole exome sequencing
Genetic
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
1 Hour to 5 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Oct 15, 2026, 4:23 AM EDT
Withdrawn Not applicable Interventional

Rib Microtia and the Erector Spinae Plane (ESP) Block

NCT03729427
View directory record Official record
Conditions
Microtia, Congenital, Microtia, Anesthesia, Local, Anesthesia
Interventions
Erector Spinae Plane Block
Procedure
Lead sponsor
Stanford University
Other
Eligibility
2 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 15, 2026, 4:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project ASPIRE Efficacy Pilot: Achieving Superior Parental Involvement for Rehabilitative Excellence

NCT01753661
View directory record Official record
Conditions
Parental Language Behaviors
Interventions
Linguistic Feedback Report, Multimedia Education Sessions, EI-As-Usual
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
6 Months and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 3, 2016 · Synced Oct 15, 2026, 4:23 AM EDT
Completed Phase 2 Interventional

Randomized Clinical Trial of Nasal Turbinate Reduction to Improve Continuous Positive Airway Pressure (CPAP) Outcomes for Sleep Apnea

NCT00503802
View directory record Official record
Conditions
Sleep Apnea Syndromes, Nasal Obstruction, Turbinate Hypertrophy
Interventions
Radiofrequency Turbinate Reduction, Sham RF
Procedure
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 80 Years
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
3
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 19, 2013 · Synced Oct 15, 2026, 4:23 AM EDT