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ClinicalTrials.gov public records Last synced Oct 7, 2026, 12:18 AM EDT

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Showing 25–47 of 47 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Out-of-Hospital Cardiac Arrest Clear all
Recruiting No phase listed Observational

International Device Assisted Controlled Sequential Elevation CPR Registry

NCT05588024
View directory record Official record
Conditions
Cardiac Arrest, Out-Of-Hospital
Interventions
Head Up CPR based bundle of care
Device
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 7, 2026, 12:18 AM EDT
Recruiting Not applicable Interventional

Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

NCT05376267
View directory record Official record
Conditions
Cardiac Arrest, Out-Of-Hospital, Hypothermia, Induced, Hypoxia-Ischemia, Brain
Interventions
Therapeutic Hypothermia
Device
Lead sponsor
University of Michigan
Other
Eligibility
2 Days to 17 Years
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
52
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 44 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 7, 2026, 12:18 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Clinical Trial of Sodium Nitrite for Out of Hospital Cardiac Arrest

NCT03452917
View directory record Official record
Conditions
Out-Of-Hospital Cardiac Arrest
Interventions
Placebo, sodium nitrite 45 mg, sodium nitrite 60 mg
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,502 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Oct 7, 2026, 12:18 AM EDT
Completed Phase 4 Interventional Results available

Continuous Chest Compressions vs AHA Standard CPR of 30:2

NCT01372748
View directory record Official record
Conditions
Out of Hospital Cardiac Arrest
Interventions
Standard CPR, Continuous chest compressions
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
23,711 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
5
States / cities
Birmingham, Alabama • Pittsburgh, Pennsylvania • Dallas, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 28, 2016 · Synced Oct 7, 2026, 12:18 AM EDT
Not listed No phase listed Observational

Save Hearts in Arizona Registry and Education (SHARE) Project

NCT01999036
View directory record Official record
Conditions
Out-of-hospital Cardiac Arrest
Interventions
Not listed
Lead sponsor
University of Arizona
Other
Eligibility
Not listed
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2020
U.S. locations
1
States / cities
Multiple Locations, Arizona
Source: ClinicalTrials.gov public record
Updated May 9, 2018 · Synced Oct 7, 2026, 12:18 AM EDT
Recruiting Not applicable Interventional

First Responder Airway & Compression Rate Trial

NCT05969028
View directory record Official record
Conditions
Out-Of-Hospital Cardiac Arrest
Interventions
igel, Compression Rate
Device · Procedure
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
4,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Oct 7, 2026, 12:18 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Dose-Finding Study of Intranasal Insulin in Healthy Participants Insulin in Healthy Participants

NCT05062785
View directory record Official record
Conditions
Out-Of-Hospital Cardiac Arrest, Healthy
Interventions
Intranasal insulin
Drug
Lead sponsor
Robert Silbergleit
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 7, 2026, 12:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Trial to Study the Feasibility and Acceptability of an App to Support Pediatric Resuscitation

NCT06768099
View directory record Official record
Conditions
Pediatric Emergency Medicine, Resuscitation, Pediatrics, Emergency Medical Services, Arrest Cardio Respiratory
Interventions
Linear Cognitive Aid
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
222 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 7, 2026, 12:18 AM EDT
Completed Not applicable Interventional

SmartCPR Trial: An Analysis of a Waveform-Based Automated External Defibrillation (AED) Algorithm on Survival From Out-of-Hospital Ventricular Fibrillation

NCT00535106
View directory record Official record
Conditions
Ventricular Fibrillation, Cardiac Arrest
Interventions
Automated external defibrillator (Philips FR2+ AED), SmartCPR, Delayed defibrillation
Device · Other
Lead sponsor
New York City Fire Department
Government
Eligibility
Not listed
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 19, 2009 · Synced Oct 7, 2026, 12:18 AM EDT
Recruiting No phase listed Observational

Resuscitative TEE Collaborative Registry

NCT04972526
View directory record Official record
Conditions
Cardiac Arrest, Cardiac Arrest Circulatory, Cardiac Arrest, Out-Of-Hospital, Shock, Hemodynamic Instability
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 7, 2026, 12:18 AM EDT
Recruiting Not applicable Interventional

The Effect of SPecialty cAre on Recovery From Cardiac Arrest Trial (the SPARC Trial)

NCT07002294
View directory record Official record
Conditions
Cardiac Arrest (CA), Heart Arrest, Heart Arrest, Out-Of-Hospital
Interventions
Transfer to specialty care, Usual care
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
1,618 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 7, 2026, 12:18 AM EDT
Active, not recruiting Not applicable Interventional

AED 3 Post-Approval Study

NCT05013333
View directory record Official record
Conditions
Cardiac Arrest, Out-Of-Hospital
Interventions
AED 3 with Uni-padz
Device
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
Not listed
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
2
States / cities
Buffalo, New York • Latham, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 7, 2026, 12:18 AM EDT
Enrolling by invitation Not applicable Interventional

Increasing Law Enforcement Application of Automated External Defibrillators (AED)s for Cardiac Arrest

NCT07649616
View directory record Official record
Conditions
Heart Arrest, Out-Of-Hospital, Defibrillators
Interventions
AED training adjunct
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 7, 2026, 12:18 AM EDT
Completed Not applicable Interventional Results available

ECPR for Refractory Out-Of-Hospital Cardiac Arrest

NCT03065647
View directory record Official record
Conditions
Cardiac Arrest, Heart Arrest, Sudden Cardiac Arrest, Cardiopulmonary Arrest, Death, Sudden, Cardiac, Cardiopulmonary Resuscitation, CPR, Extracorporeal Cardiopulmonary Resuscitation, Extracorporeal Membrane Oxygenation
Interventions
Expedited Transport With Mechanical CPR
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Oct 7, 2026, 12:18 AM EDT
Completed Phase 2 Interventional

Effect of Xenon and Therapeutic Hypothermia, on the Brain and on Neurological Outcome Following Brain Ischemia in Cardiac Arrest Patients

NCT00879892
View directory record Official record
Conditions
Ischemic Brain Injury
Interventions
xenon, Hypothermia
Drug · Other
Lead sponsor
Turku University Hospital
Government
Eligibility
18 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 19, 2015 · Synced Oct 7, 2026, 12:18 AM EDT
Not yet recruiting Phase 3 Interventional

Xenon for Neuroprotection During Post-Cardiac Arrest Syndrome in Comatose Survivors of an Out of Hospital Cardiac Arrest

NCT03176186
View directory record Official record
Conditions
Post-Cardiac Arrest Syndrome
Interventions
Xenon
Combination Product
Lead sponsor
Invero Pharma, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
1,436 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
8
States / cities
Hartford, Connecticut • Gainesville, Florida • Gulfport, Mississippi + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Oct 7, 2026, 12:18 AM EDT
Not yet recruiting Phase 2 Interventional

Naloxone for Opioid Associated Out of Hospital Cardiac Arrest

NCT06251609
View directory record Official record
Conditions
Heart Arrest, Out-Of-Hospital, Opioid Overdose, Naloxone
Interventions
Naloxone 2 MG, Saline 2ml
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 7, 2026, 12:18 AM EDT
Completed Not applicable Interventional Results available

A Pilot Study of Intra-arrest Therapeutic Hypothermia in Patients Suffering Non-Traumatic Out of Hospital Cardiac Arrest

NCT01413399
View directory record Official record
Conditions
Out-of-Hospital Cardiac Arrest
Interventions
4 degree chilled saline
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 110 Years
Enrollment
542 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Oct 7, 2026, 12:18 AM EDT
Completed No phase listed Observational

Head-to-pelvis Computed Tomography Evaluation of Sudden Death Survivors

NCT03111043
View directory record Official record
Conditions
Sudden Death, Out-Of-Hospital Cardiac Arrest
Interventions
Head to pelvis CT scan
Diagnostic Test
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 9, 2024 · Synced Oct 7, 2026, 12:18 AM EDT
Terminated Not applicable Interventional Results available

ResQ Trial: Impact of an ITD and Active Compression Decompression CPR on Survival From Out-of-Hospital Cardiac Arrest

NCT00189423
View directory record Official record
Conditions
Heart Arrest, Death, Sudden, Cardiac, Cardiopulmonary Resuscitation, Cardiac Arrest
Interventions
Use of an impedance threshold device (ITD) during the performance of active compression decompression CPR (ACD-CPR), Standard cardiopulmonary resuscitation (S-CPR)
Device · Procedure
Lead sponsor
Advanced Circulatory Systems
Industry
Eligibility
18 Years and older
Enrollment
1,653 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
7
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan • Royal Oak, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 8, 2017 · Synced Oct 7, 2026, 12:18 AM EDT
Completed Not applicable Interventional Results available

Pragmatic Airway Resuscitation Trial

NCT02419573
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Endotracheal Intubation, Laryngeal Tube (King)
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
3,004 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
6
States / cities
Birmingham, Alabama • Portland, Oregon • Pittsburgh, Pennsylvania + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Oct 7, 2026, 12:18 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Induction of Mild Hypothermia Following Out-of-hospital Cardiac Arrest

NCT00391469
View directory record Official record
Conditions
Out-of-hospital Cardiac Arrest
Interventions
Rapid infusion of 2 liters of 4oC normal saline, Rapid infusion of cold normal saline
Other · Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,359 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Oct 7, 2026, 12:18 AM EDT
Completed No phase listed Observational Results available

Pre-arrival Instructions Effect on Bystander Cardiopulmonary Resuscitation (CPR).

NCT02007499
View directory record Official record
Conditions
Heart Arrest, Cardiac Arrest, Cardiopulmonary Arrest, Out of Hospital Cardiac Arrest, Sudden Cardiac Death
Interventions
Pre-Arrival Instructions
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
21 Years and older
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 7, 2026, 12:18 AM EDT