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ClinicalTrials.gov public records Last synced Oct 22, 2026, 5:56 PM EDT

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Showing 1–24 of 5,747 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Overweight Clear all
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

A Study of LY4167586 in Participants With Obesity or Overweight Who Are Otherwise Healthy

NCT07225556
View directory record Official record
Conditions
Overweight, Obesity
Interventions
LY4167586, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 22, 2026, 5:56 PM EDT
Not listed Not applicable Interventional

Impact of Acute Exercise on Vascular Insulin Sensitivity in Metabolic Syndrome

NCT03894527
View directory record Official record
Conditions
Metabolic Syndrome, Obesity
Interventions
Single Bout of Exercise, Control Condition
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
40 Years to 70 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 28, 2019 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Beneficial Effects of Healthy Snacks on Appetite Control, Satiety, and Reward-driven Eating Behavior in Young People

NCT01781286
View directory record Official record
Conditions
Obesity
Interventions
High Protein, Low Protein
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
13 Years to 19 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 23, 2018 · Synced Oct 22, 2026, 5:56 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Metabolic Effects of Intermittent Fasting

NCT05722873
View directory record Official record
Conditions
Normal and Overweight Individuals at High-risk of Diabetes
Interventions
Fasting arm, Weight maintenance, Counseling
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years to 45 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Phase 4 Interventional Results available

Metformin for Overweight & OBese ChILdren and Adolescents With BDS Treated With SGAs

NCT02515773
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Metformin, healthy lifestyle intervention (LIFE)
Drug · Behavioral
Lead sponsor
Melissa Delbello
Other
Eligibility
8 Years to 19 Years
Enrollment
1,565 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
29
States / cities
Covington, Kentucky • Neptune City, New Jersey • Amityville, New York + 13 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Not applicable Interventional

Success in Health: Impacting Families Together

NCT02580162
View directory record Official record
Conditions
Childhood Obesity
Interventions
FBT for Pediatric Weight Management by Professionals, FBT for Pediatric Weight Management by Peers, Peer Interventionists
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
7 Years to 11 Years
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 1, 2021 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

HELP Prevent Cancer Pilot Study

NCT02960542
View directory record Official record
Conditions
Obesity, Cancer
Interventions
HELP Prevent Cancer Intervention
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Danville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 19, 2020 · Synced Oct 22, 2026, 5:56 PM EDT
Completed No phase listed Observational

Evaluation of a Weight Management Program

NCT00888251
View directory record Official record
Conditions
Obesity
Interventions
Comprehensive weight management program
Other
Lead sponsor
Société des Produits Nestlé (SPN)
Industry
Eligibility
Not listed
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
4
States / cities
Fort Wayne, Indiana • Des Moines, Iowa • East Lansing, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2011 · Synced Oct 22, 2026, 5:56 PM EDT
Recruiting Not applicable Interventional

Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer

NCT06106477
View directory record Official record
Conditions
Breast Cancer
Interventions
Intermittent Fasting
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Not applicable Interventional

Dyad Plus Effectiveness/Feasibility

NCT04036331
View directory record Official record
Conditions
Weight Loss, Pediatric Obesity, Overweight Adolescents, Parent-Child Relations, Family and Household
Interventions
Brenner FIT Standard, By Design Essentials, Dyad Plus
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
13 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Not applicable Interventional

Starting Early to Prevent Obesity Using Telehealth (StEP OUT): Intervention Development Trial

NCT06486922
View directory record Official record
Conditions
Child Obesity, Breast Feeding, Feeding Behavior, Nutrition, Healthy
Interventions
StEP OUT
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older · Female only
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Not applicable Interventional

Effects of Yerba Mate Supplementation on Metabolic Health, Physical Function, and Cognition in Older Adults With Excess Adiposity

NCT07883031
View directory record Official record
Conditions
Overweight (BMI > 25), Obesity & Overweight
Interventions
Yerba Mate, Placebo
Dietary Supplement
Lead sponsor
University of North Alabama
Other
Eligibility
60 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Florence, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 22, 2026, 5:56 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing Lifestyles Through Increased Vegetable-rich Eating Pilot Study

NCT07509502
View directory record Official record
Conditions
Type 2 Diabetes (T2DM), Obesity & Overweight
Interventions
Dietary Intervention Teaching Kitchen (TK) Classes, Food is Medicine Grocery Provision (FiM)
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Clinical Study to Investigate the Effect of SAR425899 on Energy Expenditure in Obese Subjects

NCT03376802
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
SAR425899, Placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years to 50 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
2
States / cities
Orlando, Florida • Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Oct 22, 2026, 5:56 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Taste Reward Processing in Pediatric Obesity

NCT01908153
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
4 Years to 8 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2019 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise Training and Time-restricted Feeding in Overweight and Obese Adults

NCT03823872
View directory record Official record
Conditions
Overweight and Obesity, Weight Loss
Interventions
Time restricted feeding, Normal feeding
Other
Lead sponsor
Kyle Hackney
Other
Eligibility
35 Years to 60 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Aug 25, 2020 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Phase 2 Interventional Results available

Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists

NCT06640972
View directory record Official record
Conditions
Triglycerides, Weight Gain Trajectory, Cholesterol, Elevated
Interventions
RDX-002, Placebo
Drug
Lead sponsor
Response Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Not applicable Interventional Results available

W8Loss2Go: mHealth Weight Management Strategy

NCT02689154
View directory record Official record
Conditions
Obesity
Interventions
W8Loss2Go
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
12 Years to 18 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2019 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Weight Loss Study-Mechanism Underlying the Improvement of Insulin Resistance in Response to Weight Loss

NCT01780870
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Weight loss group (Full meal replacement products)
Dietary Supplement
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 7, 2017 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Sleep Restriction in Women

NCT02835261
View directory record Official record
Conditions
Sleep, Cardiovascular Disease, Obesity
Interventions
Sleep Restriction
Other
Lead sponsor
Columbia University
Other
Eligibility
20 Years to 75 Years · Female only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Not applicable Interventional

Intermittent Fasting in Adults With Type 1 Diabetes

NCT06134986
View directory record Official record
Conditions
Type 1 Diabetes, Obesity
Interventions
Time restricted eating, Daily calorie restriction
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 22, 2026, 5:56 PM EDT
Recruiting Phase 2 Interventional

Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients

NCT04721873
View directory record Official record
Conditions
Colitis, Ulcerative, Obesity
Interventions
Phentermine-Topiramate, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Oct 22, 2026, 5:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Patient-Clinic-Community Integration to Prevent Obesity Among Rural Preschool Children

NCT04406441
View directory record Official record
Conditions
Pediatric Obesity, Preventive Medicine, Mentoring, Food Supply
Interventions
Patient Reported Outcome Well Child Visit, Patient Reported Outcome Well Child Visit + Food Care
Behavioral
Lead sponsor
Geisinger Clinic
Other
Eligibility
20 Months to 59 Months
Enrollment
2,040 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 22, 2026, 5:56 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Diet, Exercise and Body Fat in 3-5 Year Olds

NCT00615641
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
3 Years to 5 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 17, 2010 · Synced Oct 22, 2026, 5:56 PM EDT