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Showing 1–24 of 5,444 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Overweight , Obesity Clear all
Completed Phase 2Phase 3 Interventional Results available

Effectiveness of Higher Aspirin Dosing for Prevention of Preeclampsia in High Risk Obese Gravida

NCT03961360
View directory record Official record
Conditions
Pre-Eclampsia, Hypertension in Pregnancy, Obesity
Interventions
Aspirin 81 mg, Aspirin 162 mg
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Phase 4 Interventional Results available

Study to Evaluate Weight-based Enoxaparin Dosing in Obese Medical Patients at Risk for DVT

NCT00585182
View directory record Official record
Conditions
Obesity, Venous Thrombosis, Anticoagulants
Interventions
Enoxaparin 0.5 mg/kg once daily
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Not applicable Interventional Results available

Adaptation of a Digital Weight Loss Intervention Promoting Self-regulation for Use in Type 2 Diabetes

NCT03650088
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Overweight and Obesity
Interventions
Behavioral weight loss with digital tools
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 12, 2023 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Phase 4 Interventional Results available

A Multicenter, Double-blind, Randomized, Parallel-group, Pilot Study of 12-week Duration to Assess the Short-term Safety and Tolerability of Lorcaserin Plus Two Doses of Immediate-Release Phentermine-HCl Compared With Lorcaserin Alone in Overweight and Obese Adults

NCT01987427
View directory record Official record
Conditions
Chronic Weight Management
Interventions
lorcaserin + phentermine placebo, lorcaserin + phentermine-HCl + phentermine placebo, lorcaserin + phentermine-HCl
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
13
States / cities
Birmingham, Alabama • Chandler, Arizona • La Jolla, California + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2019 · Synced Jun 25, 2026, 9:08 PM EDT
Terminated Phase 3 Interventional

Double-Blind, Placebo Controlled, Phase 3 Trial of ZGN-440 (Beloranib) in Obese Subjects With Prader-Willi Syndrome

NCT02179151
View directory record Official record
Conditions
Prader-Willi Syndrome, Obesity
Interventions
ZGN-440 for Injectable Suspension, ZGN-440 Placebo for Injectable Suspension
Drug
Lead sponsor
Zafgen, Inc.
Industry
Eligibility
12 Years to 65 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
15
States / cities
Sacramento, California • San Diego, California • Aurora, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2017 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mechanisms of Obesity and Its Metabolic Complications in Youth

NCT03454828
View directory record Official record
Conditions
Obesity, Childhood
Interventions
obese carbohydrate diet, lean carbohydrate diet
Dietary Supplement
Lead sponsor
Yale University
Other
Eligibility
15 Years to 21 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Jun 25, 2026, 9:08 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

FFA Metabolism in Different Types of Human Obesity

NCT00068900
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2004
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 29, 2015 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Metabolism, Exercise and Nutrition at UCSD (MENU Study)

NCT01424007
View directory record Official record
Conditions
Obese, Nondiabetic
Interventions
Weight loss
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years and older · Female only
Enrollment
245 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 4, 2019 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Not applicable Interventional

Metabolically Normal and Metabolically Abnormal Obesity

NCT01184170
View directory record Official record
Conditions
Obesity, Metabolic Syndrome
Interventions
overfeeding
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Not applicable Interventional

Tailoring a Lifestyle Intervention to Address Obesity Disparities Among Men

NCT03037502
View directory record Official record
Conditions
Weight Loss, Obesity
Interventions
Tailor Made: Solutions for your health (A su Medida: Soluciones para su salud)
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
35 Years to 64 Years · Male only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Miami, Florida • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Beneficial Effects of a Protein-rich Breakfast on Appetite Control & Cognition in Overweight and Obese Adolescents

NCT01192100
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Breakfast Skipping, Normal Protein Breakfast Meals, Protein-rich Breakfast Meals
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
15 Years to 20 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Not applicable Interventional Results available

Dissemination and Implementation of Improving Pediatric Obesity Practice Using Prompts

NCT05627011
View directory record Official record
Conditions
Obesity, Childhood
Interventions
Improving Pediatric Obesity Practice Using Prompts (iPOP-UP)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
2 Years and older
Enrollment
58,364 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
3
States / cities
Indianapolis, Indiana • Durham, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dysregulation of FSH in Obesity: Functional and Statistical Analysis

NCT02478775
View directory record Official record
Conditions
Obesity, Fertility
Interventions
Degarelix (GnRH antagonist), recombinant FSH, Cetrorelix
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 39 Years · Female only
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peer-delivered and Technology-Assisted Integrated Illness Management and Recovery

NCT04481737
View directory record Official record
Conditions
Schizophrenia, Bipolar Disorder, Major Depressive Disorder, Recurrent, Obesity, Cardiovascular Diseases, Diabetes, Smoking, Blood Pressure Disorders, Cholesterol, Elevated
Interventions
Peer-delivered and Technology Support Integrated Illness Management and Recovery, Peer support
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Not applicable Interventional

Heart Obesity Prevention Education

NCT02092545
View directory record Official record
Conditions
Obesity
Interventions
Ketogenic diet
Other
Lead sponsor
Tampa General Hospital
Other
Eligibility
25 Years to 64 Years · Male only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 18, 2014 · Synced Jun 25, 2026, 9:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating Parental Influences on Obesity Among Mexican American Children

NCT00542672
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
8 Years to 10 Years
Enrollment
831 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 21, 2013 · Synced Jun 25, 2026, 9:08 PM EDT
Enrolling by invitation Not applicable Interventional

ESG in Obese Adolescents

NCT06914765
View directory record Official record
Conditions
Obese Adolescents, Obesity, Morbid, Obesity/Therapy
Interventions
Endoscopic Sleeve Gastroplasty (ESG) Procedure
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fatty Acid Metabolism and Insulin Sensitivity After Exercise in Obesity

NCT01451957
View directory record Official record
Conditions
Obesity
Interventions
Exercise - caloric balance, No Exercise - hyper-caloric diet, No exercise - caloric balance
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 22, 2016 · Synced Jun 25, 2026, 9:08 PM EDT
Completed No phase listed Observational

Endotoxin and Intestinal Flora Before and After Gastric Bypass or Banding in Diabetics

NCT00960765
View directory record Official record
Conditions
Obesity, Morbid, Diabetes Mellitus, Type 2, Gastric Bypass
Interventions
Not listed
Lead sponsor
CPL Associates
Other
Eligibility
18 Years to 95 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
2
States / cities
Buffalo, New York • Williamsville, New York
Source: ClinicalTrials.gov public record
Updated Jan 27, 2016 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Not applicable Interventional Results available

Neurological Impacts of Artificial Sweeteners in the Context of Diet Sodas

NCT04048681
View directory record Official record
Conditions
Obesity
Interventions
diet soda, Regular soda, Carbonated Water
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Phase 1 Interventional Results available

A Study to Measure Stomach Emptying in Overweight Non-diabetic and Diabetic Participants Using Tirzepatide

NCT04407234
View directory record Official record
Conditions
Overweight, Obesity, Diabetes Mellitus, Type 2
Interventions
Tirzepatide, Acetaminophen
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Hialeah, Florida
Source: ClinicalTrials.gov public record
Updated Jan 7, 2024 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Not applicable Interventional

Managing Patient Expectations in Pediatric Weight Management

NCT01753063
View directory record Official record
Conditions
Obesity
Interventions
Patient Expectations
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Years to 18 Years
Enrollment
405 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
12
States / cities
Denver, Colorado • Hartford, Connecticut • Peoria, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2013 · Synced Jun 25, 2026, 9:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Piloting a Reinforcement Learning Tool for Individually Tailoring Just-in-time Adaptive Interventions

NCT05751993
View directory record Official record
Conditions
Overweight and Obesity, Overweight, Obesity
Interventions
ADAPT
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 55 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Jun 25, 2026, 9:08 PM EDT
Active, not recruiting Not applicable Interventional Results available

Effect of Time-restricted Eating on Catecholamine-sensitivity of Adipose Tissue in Obese Adults

NCT04916730
View directory record Official record
Conditions
Obesity
Interventions
Standard of Care, Time Restricted Eating
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Jun 25, 2026, 9:08 PM EDT