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ClinicalTrials.gov public records Last synced Oct 19, 2026, 11:26 AM EDT

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Showing 145–168 of 575 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: PAD - Peripheral Arterial Disease Clear all
Completed Not applicable Interventional

Revascularization With Open Bypass Versus Angioplasty and STenting of the Lower Extremity Trial (ROBUST)

NCT01602159
View directory record Official record
Conditions
Superficial Femoral Artery Stenosis, Superficial Femoral Artery Occlusion, Claudication, Rest Pain
Interventions
Open Bypass Surgery, Angioplasty and Stenting
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 28, 2018 · Synced Oct 19, 2026, 11:26 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

The Pharmacokinetics and Pharmacodynamics Study of Evategrel CG-0255 Besylate）and Plavix® in Healthy Participants

NCT07619885
View directory record Official record
Conditions
Acute Coronary Syndromes (ACS), Recent Myocardial Infarction, Recent Stroke, Peripheral Arterial Disease
Interventions
CG-0255 Besylate for Injection, CG-0255 Besylate Capsule, Clopidogrel
Drug
Lead sponsor
Shanghai CureGene Pharmaceutical Co., Ltd.
Industry
Eligibility
18 Years to 55 Years
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 19, 2026, 11:26 AM EDT
Completed Phase 2 Interventional Results available

Phase IIa: Safety, PK, & Tolerability of Sodium Nitrite in Patients With Peripheral Arterial Disease-SONIC

NCT01401517
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
sodium nitrite
Drug
Lead sponsor
TheraVasc Inc.
Industry
Eligibility
35 Years to 85 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
10
States / cities
Aurora, Colorado • Atlanta, Georgia • Iowa City, Iowa + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2020 · Synced Oct 19, 2026, 11:26 AM EDT
Completed No phase listed Observational

Comparison of Prosthetic Femoropopliteal Bypass Versus Viabahn Endoprosthesis for Treatment of Symptomatic Femoral Artery Occlusion

NCT00962897
View directory record Official record
Conditions
Atherosclerosis, Lower Extremity Ischemia, Claudication, Rest Pain
Interventions
Femoral-popliteal bypass, Stent-graft placement
Procedure
Lead sponsor
Texas Vascular Associates
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2009 · Synced Oct 19, 2026, 11:26 AM EDT
Active, not recruiting Not applicable Interventional

MOTIV BTK Randomized Controlled Trial

NCT05406622
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
MOTIV Sirolimus-Eluting Bioresorbable Scaffold, Percutaneous Transluminal Angioplasty (PTA) Device
Device
Lead sponsor
REVA Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
292 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2030
U.S. locations
25
States / cities
El Centro, California • Fremont, California • St. Helena, California + 22 more
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 19, 2026, 11:26 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease

NCT06319339
View directory record Official record
Conditions
Peripheral Artery Disease, Peripheral Vascular Diseases, Peripheral Arterial Disease, Peripheral Arterial Occlusive Disease
Interventions
Vumerity, Placebo
Drug · Other
Lead sponsor
University of Nebraska
Other
Eligibility
50 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 19, 2026, 11:26 AM EDT
Not yet recruiting No phase listed Observational

PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study

NCT05377320
View directory record Official record
Conditions
Heart Failure, Coronary Artery Disease, Peripheral Artery Disease, Ischemia, Hypertension, Diabetes Mellitus, Cardiomyopathies, Cardiotoxicity
Interventions
Clinical Decision Aid, Standard Care
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
60 participants
Timeline
2026 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 19, 2026, 11:26 AM EDT
Recruiting No phase listed Observational

Advanta VXT and Flixene PMCF Registry

NCT07161583
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Advanta VXT Vascular Graft, Flixene Vascular Graft
Device
Lead sponsor
Atrium Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 19, 2026, 11:26 AM EDT
Completed Phase 2 Interventional

A Study of CK-2017357 in Patients With Peripheral Artery Disease and Symptomatic Claudication

NCT01131013
View directory record Official record
Conditions
Intermittent Claudication, Peripheral Artery Disease
Interventions
Placebo, 375 mg CK-2017357, 500 mg CK-2017357
Drug
Lead sponsor
Cytokinetics
Industry
Eligibility
40 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
14
States / cities
Phoenix, Arizona • Santa Ana, California • Stanford, California + 11 more
Source: ClinicalTrials.gov public record
Updated May 14, 2019 · Synced Oct 19, 2026, 11:26 AM EDT
Completed Not applicable Interventional Results available

Ankle-foot Orthoses for Peripheral Artery Disease

NCT02280200
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
AFO to improve outcomes
Device
Lead sponsor
University of Minnesota
Other
Eligibility
40 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Missoula, Montana
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Oct 19, 2026, 11:26 AM EDT
Completed Phase 2 Interventional Results available

A Phase 2 Study of the Effects of Sapropterin Dihydrochloride on Symptomatic Peripheral Arterial Disease

NCT00403494
View directory record Official record
Conditions
Intermittent Claudication
Interventions
Placebo, Sapropterin Dihydrochloride
Other · Drug
Lead sponsor
BioMarin Pharmaceutical
Industry
Eligibility
40 Years to 80 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
17
States / cities
Scottsdale, Arizona • Sacramento, California • San Diego, California + 14 more
Source: ClinicalTrials.gov public record
Updated Jan 7, 2021 · Synced Oct 19, 2026, 11:26 AM EDT
Recruiting No phase listed Observational

MRI Guided Management of Occlusive Peripheral Arterial Disease

NCT06782100
View directory record Official record
Conditions
Peripheral Vascular Diseases
Interventions
Not listed
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 19, 2026, 11:26 AM EDT
Recruiting Phase 2 Interventional

Passive Stretching in Peripheral Arterial Disease Patients

NCT06420752
View directory record Official record
Conditions
Peripheral Arterial Disease, Walking, Difficulty, Inflammation
Interventions
Calf Plantar flexion, Dietary nitrate
Device · Dietary Supplement
Lead sponsor
University of Wisconsin, La Crosse
Other
Eligibility
40 Years to 90 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
La Crosse, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Oct 19, 2026, 11:26 AM EDT
Recruiting No phase listed Observational

Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status

NCT06009276
View directory record Official record
Conditions
Heart Failure, Systolic, Heart Failure, Diastolic, Peripheral Arterial Disease, Overweight and Obesity
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
70 participants
Timeline
2023 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 19, 2026, 11:26 AM EDT
Recruiting Phase 3 Interventional

Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease

NCT07318610
View directory record Official record
Conditions
Peripheral Artery Disease (PAD)
Interventions
REGN7508, REGN9933, Placebo, Rivaroxaban
Drug
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
7,050 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
21
States / cities
Alexander City, Alabama • Avondale, Arizona • Little Rock, Arkansas + 18 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 19, 2026, 11:26 AM EDT
Completed Not applicable Interventional

Exercise for Elderly Peripheral Revascularized Patients

NCT00667290
View directory record Official record
Conditions
Peripheral Artery Disease, Intermittent Claudication
Interventions
Treadmill exercise
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
40 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2007
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 28, 2008 · Synced Oct 19, 2026, 11:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise Rehabilitation in Veterans With PAD

NCT02607046
View directory record Official record
Conditions
Peripheral Arterial Disease, Intermittent Claudication
Interventions
Exercise training, NMES
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 80 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Oct 19, 2026, 11:26 AM EDT
Completed Not applicable Interventional

Laser Atherectomy Versus Angioplasty for the Treatment of Critical Limb Ischemia

NCT01579123
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
Angioplasty, Laser atherectomy
Procedure
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
3
States / cities
Dallas, Texas • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jan 19, 2018 · Synced Oct 19, 2026, 11:26 AM EDT
Completed Not applicable Interventional Results available

EverFlex Post Approval Study

NCT01680835
View directory record Official record
Conditions
Peripheral Arterial Disease, Lower Extremity Arterial Disease
Interventions
EverFlex™ Self-Expanding Peripheral Stent System
Device
Lead sponsor
Medtronic Endovascular
Industry
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
23
States / cities
Phoenix, Arizona • Modesto, California • Sacramento, California + 20 more
Source: ClinicalTrials.gov public record
Updated Dec 26, 2019 · Synced Oct 19, 2026, 11:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Predicting Peripheral Arterial Disease in Men With Erectile Dysfunction

NCT00743613
View directory record Official record
Conditions
Erectile Dysfunction, Peripheral Arterial Disease
Interventions
Sexual Health Inventory for Men (SHIM), Ankle-Brachial Index (ABI)
Behavioral · Procedure
Lead sponsor
Bruton Avenue Family Practice
Other
Eligibility
50 Years and older · Male only
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
5
States / cities
Fitchburg, Massachusetts • Hampton, Virginia • Newport News, Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2008 · Synced Oct 19, 2026, 11:26 AM EDT
Terminated No phase listed Observational

Short-term Perfusion Angiography Pilot Study (SPA)

NCT03054636
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Not listed
Lead sponsor
Volcano Corporation
Industry
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
4
States / cities
Miami, Florida • Wyoming, Michigan • Raleigh, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2020 · Synced Oct 19, 2026, 11:26 AM EDT
Completed Not applicable Interventional Results available

Home-based Leg Heat Therapy

NCT03763331
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Control/Sham Treatment, Heat Therapy
Device
Lead sponsor
Indiana University
Other
Eligibility
40 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 19, 2026, 11:26 AM EDT
Completed Not applicable Interventional

Implementation of ABI and WIfI in Rural Health Clinics

NCT04337723
View directory record Official record
Conditions
Peripheral Arterial Disease, Diabetic Foot, Diabetes Mellitus
Interventions
ABI/WIFI scoring
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Oct 19, 2026, 11:26 AM EDT
Completed Phase 3 Interventional Results available

Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

NCT03473223
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Apolipoprotein A-I [human] (apoA-I), Placebo
Biological · Other
Lead sponsor
CSL Behring
Industry
Eligibility
18 Years and older
Enrollment
18,226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
202
States / cities
Alexander City, Alabama • Birmingham, Alabama • Huntsville, Alabama + 175 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Oct 19, 2026, 11:26 AM EDT