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ClinicalTrials.gov public records Last synced Nov 4, 2026, 12:51 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 721–744 of 10,295 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: PAIN Clear all

Conditions: Total Knee Arthroplasty
Interventions: Dexamethasone 4mg, Dexamethasone 8 Mg/mL Injectable Suspension, Dexamethasone 16mg; Drug
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 438 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 10
States / cities: Redwood City, California • San Francisco, California • Chicago, Illinois + 5 more

Conditions: Lumbar Disc Disease
Interventions: NOCISCAN-LS Disc MR Spectroscopy; Other
Lead sponsor: Nocimed, LLC; Other
Eligibility: 18 Years to 70 Years
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Plano, Texas

Conditions: Pain
Interventions: Hydrocodone/Acetaminophen Extended Release, Placebo; Drug
Lead sponsor: Abbott; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2004
U.S. locations: 4
States / cities: Owing Mills, Maryland • Austin, Texas • San Marcos, Texas + 1 more

Conditions: Pelvic Pain
Interventions: BTL Emsella chair; Device
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years to 80 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Pain Management
Interventions: Active BreEStim Treatment, Sham BreEStim Treatment, The TENS Treatment; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 22 Years to 80 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Depression, Anxiety, Opioid-Related Disorders, Pain, Chronic
Interventions: More Individualized Care: Assessment and Recovery through Engagement (MI-CARE); Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 805 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 2
States / cities: Indianapolis, Indiana • Seattle, Washington

Conditions: Refractive Surgery
Interventions: Dextenza 0.4Mg Ophthalmic Insert, Topical Prednisolone; Drug
Lead sponsor: Vance Thompson Vision; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Sioux Falls, South Dakota

Conditions: Smoking Cessation
Interventions: Cognitive behavioral, Control; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 80 Years
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Drug Interactions
Interventions: Oxycodone, Hydrocodone, Ondansetron; Drug
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 95 Years
Enrollment: 502 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Appendicitis
Interventions: Appy CDS; Other
Lead sponsor: HealthPartners Institute; Other
Eligibility: 5 Years to 20 Years
Enrollment: 5,940 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Oakland, California • Minneapolis, Minnesota

Conditions: Angina, Chest Pain
Interventions: Cardiac MRI; Other
Lead sponsor: Piedmont Healthcare; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Postoperative Pain
Interventions: Hydromorphone; Drug
Lead sponsor: Purdue Pharma LP; Industry
Eligibility: 28 Days to 16 Years
Enrollment: 116 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 14
States / cities: Little Rock, Arkansas • Orange, California • Stanford, California + 10 more

Conditions: Spinal Degenerative Disorder, Spinal Stenosis, Spondylosis
Interventions: Physical activity intervention, Usual care; Behavioral · Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Low Back Pain
Interventions: aquatic vertical suspension., land-based supine flexion; Other
Lead sponsor: Texas Tech University Health Sciences Center; Other
Eligibility: 40 Years to 80 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Cleburne, Texas

Conditions: Musculoskeletal Pain
Interventions: Pain Catastrophizing Induction; Behavioral
Lead sponsor: Beth Darnall, PhD; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Wound Vac, Suture
Interventions: Polypropylene Suture Right Side, Polypropylene Suture Left Side; Other
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Experimental Pain, Low Back Pain
Interventions: No intervention; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 60 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 2
States / cities: Tallahassee, Florida • Charlestown, Massachusetts

Conditions: Mechanical Low Back Pain
Interventions: Patient Decision Making tool, Standard of care; Behavioral · Other
Lead sponsor: Walsh University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Arthralgia, Musculoskeletal Complications, Pain, Recurrent Breast Cancer, Stage I Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer
Interventions: letrozole, calcium carbonate, laboratory biomarker analysis, calcium citrate, calcium glucarate, calcium gluconate, cholecalciferol, assessment of therapy complications, musculoskeletal complications management/prevention; Drug · Dietary Supplement · Other + 1 more
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Carbohydrate Intolerance
Interventions: Low-FODMAP diet group (LFD), Low Sugar diet group (LAS); Other
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 5 Years to 18 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Springfield, Oregon

Conditions: Pain, Constipation, Nausea, Vomiting
Interventions: Lidocaine, Esmolol, Lidocaine + Esmolol (Combo); Drug
Lead sponsor: Cedars-Sinai Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Pain
Interventions: 4975, Placebo; Drug
Lead sponsor: Anesiva, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 6
States / cities: Bakersfield, California • Owings Mills, Maryland • Austin, Texas + 3 more

Conditions: Fibromyalgia
Interventions: Placebo, Milnacipran; Drug
Lead sponsor: Forest Laboratories; Industry
Eligibility: Not listed
Enrollment: 340 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2009
U.S. locations: 58
States / cities: Birmingham, Alabama • Tucson, Arizona • Fresno, California + 51 more

Conditions: Pain, Postoperative
Interventions: Control Group - ESP block with SAP block, Treatment Group - ESP block with SAP normal saline; Drug
Lead sponsor: Anna Uskova; Other
Eligibility: 18 Years to 90 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Search by objective public record fields.

Dexamethasone in Total Knee Arthroplasty

NOCISCAN-Lumbar Spine (LS) Clinical Evaluation Study

A Study Comparing the Analgesic Activity of Extended Release Hydrocodone/Acetaminophen (Vicodin® CR) and Placebo in Subjects With Pain Following Bunionectomy Surgery

Emsella Chair Versus Sham for the Treatment of Chronic Pelvic Pain

BreEStim in Managing Neuropathic Pain After Spinal Cord Injury (SCI)

More Individualized Care: Assessment and Recovery Through Engagement

The RESTORE Study, A Randomized, Controlled, Masked (Reading Center) Prospective Study

Cognitive Behavioral Smoking Cessation Intervention for Adults With Chronic Pain

Emergency Department (ED) Drug Interaction in Emergency Department Patients

EHR-based Decision Support for Pediatric Acute Abdominal Pain in Emergency Care

Transmyocardial Laser Revascularization and Cardiovascular Magnetic Resonance Imaging

An Open-label Study of Hydromorphone Oral Solution in Subjects Aged 28 Days to 16 Years for Postoperative Pain

Physical Activity Intervention for Patients Following Lumbar Spine Surgery

Interventional Study of Effects on Spine Height With Two Unloading Positions

Pain Catastrophizing as a Cause for Systemic Inflammation

Wound Vac Polypropylene Suture Pilot Study

Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain

Influence of Patient-Informed Choice in a Novel Treatment Model for LBP

Vitamin D Deficiency, Muscle Pain, Joint Pain, and Joint Stiffness in Postmenopausal Women Receiving Letrozole For Stage I-III Breast Cancer

Impact of Two Dietary Interventions on Simple Carbohydrate Intolerance

Effect of Lidocaine and Esmolol to Improve the Quality of Recovery

Efficacy and Safety Study of 4975 to Manage Pain of Bunionectomy

Discontinuation Study of the Durability of Effect of Milnacipran for the Treatment of Fibromyalgia

Erector Spinae Plane Block vs Erector Spinae Plane Block With Serratus Anterior Plane Block in Thoracic Surgery