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ClinicalTrials.gov public records Last synced Nov 7, 2026, 7:50 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1345–1368 of 10,302 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: PAIN Clear all

Conditions: Pain, Depression, Anxiety, Musculoskeletal, Fibromyalgia
Interventions: Assisted Symptom Management (ASM), Comprehensive Symptom Management (CSM); Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 296 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Polyneuropathies
Interventions: HB-adMSCs; Biological
Lead sponsor: Hope Biosciences Research Foundation; Industry
Eligibility: Not listed
U.S. locations: 1
States / cities: Sugar Land, Texas

Conditions: Pain
Interventions: Methadone, Morphine; Drug
Lead sponsor: Stanford University; Other
Eligibility: Up to 5 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 3
States / cities: Stanford, California • Denver, Colorado • Portland, Oregon

Conditions: Low Back Pain
Interventions: Restrained Sitting Treatment; Other
Lead sponsor: Liberty Mutual Research Institute for Safety; Industry
Eligibility: 30 Years to 60 Years
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Hopkinton, Massachusetts

Conditions: Interstitial Cystitis, Sexual Dysfunction, Pelvic Pain, Incontinence
Interventions: Not listed
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years and older · Female only
Enrollment: 2,923 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2015
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Knee Osteoarthritis
Interventions: Duloxetine, Intra-Articular Injection, Nerve Procedure with long acting blocks, Nerve Procedure with nerve ablation, Pain Coping Skills Training, Best Practices; Drug · Combination Product · Procedure + 2 more
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 1,937 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 24
States / cities: Sacramento, California • San Diego, California • Aurora, Colorado + 19 more

Conditions: Fibromyalgia
Interventions: MDMA; Drug
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 21 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Charlestown, Massachusetts

Conditions: Postoperative Pain
Interventions: ESP Block with Bupivacaine, ESP Block with Bupivacaine + Liposomal Bupivacaine; Drug
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Pain, Chronic
Interventions: online patient education teach mindfulness based stress reduction; Other
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Myofascial Pain
Interventions: Magnetic Resonance (MR) Elastography, MRI structural imaging; Diagnostic Test
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Bunionectomy, Orthopedic Surgery
Interventions: Lornoxicam 8 mg, Lornoxicam 16 mg, Ketorolac 30 mg, Placebo; Drug
Lead sponsor: POZEN; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 100 participants
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: Anaheim, California

Conditions: Pain, Postoperative
Interventions: Not listed
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 75 Years
Enrollment: 2,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Pain, Acute
Interventions: virtual reality distraction (Yes VR), music distraction (No VR); Behavioral
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: 6 Years to 17 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Galveston, Texas

Conditions: Pain
Interventions: 1% Lidocaine with Epinephrine (1:100,000), 0.25% Bupivacaine with Epinephrine (1:200,000), 0.5% Lidocaine, 0.125 Bupivacaine, and epi (1:150,000), 1% Lidocaine, 0.5% Bupivacaine, and epinephrine (1:150,000); Drug
Lead sponsor: Scott and White Hospital & Clinic; Other
Eligibility: 18 Years to 60 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Temple, Texas

Conditions: Orthopedic Trauma Surgery Patients, Postoperative Pain, Opioid Use, Depression, Post-traumatic Stress Disorder (PTSD)
Interventions: Ketamine, standard general anesthesia; Drug
Lead sponsor: Texas Tech University Health Sciences Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Lubbock, Texas

Conditions: Chronic Pain, Complex Regional Pain Syndrome, Failed Back Surgery Syndrome
Interventions: Spinal cord stimulator, Implantation of a spinal cord stimulator; Device · Procedure
Lead sponsor: CHU de Quebec-Universite Laval; Other
Eligibility: 18 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Toledo, Ohio

Conditions: Hypertension, Chronic Stable Angina, Vasospastic Angina
Interventions: Amlodipine; Drug
Lead sponsor: Roxane Laboratories; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004
U.S. locations: 1
States / cities: Saint Charles, Missouri

Conditions: Low Back Pain
Interventions: self-administered acupressure; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 297 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Cancer, Breast, Cancer, Colorectal, Cancer, Lung, Cancer, Ovarian
Interventions: aerobic exercise intervention, control group, resistive training; Behavioral · Other
Lead sponsor: Baltimore VA Medical Center; Federal
Eligibility: 21 Years to 70 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Musculoskeletal Pain
Interventions: Erchonia EVRL; Device
Lead sponsor: Erchonia Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Largo, Florida • White Plains, New York

Conditions: Postoperative Pain, Abdominoplasty Surgery, Multimodal Analgesia
Interventions: MMA regimen, ZYNRELEF kit components for administration, HTX-011, Bupivacaine Hydrochloride; Drug · Device
Lead sponsor: Heron Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: Bellaire, Texas • San Antonio, Texas

Conditions: Chronic Low Back Pain
Interventions: hydrocodone/acetaminophen extended release, Placebo; Drug
Lead sponsor: AbbVie (prior sponsor, Abbott); Industry
Eligibility: 18 Years to 75 Years
Enrollment: 168 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 17
States / cities: Tucson, Arizona • Anaheim, California • Burbank, California + 14 more

Conditions: Knee Injuries, Knee Osteoarthritis, Patellofemoral Syndrome
Interventions: Limber Digital Application, Physical therapy Therapy; Device · Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Arthritis of Carpometacarpal Joint of Left Thumb, Arthritis of Carpometacarpal Joint of Right Thumb
Interventions: Curcumin, Placebo; Drug
Lead sponsor: Brent DeGeorge; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Charlottesville, Virginia

Search by objective public record fields.

Comprehensive vs. Assisted Management of Mood and Pain Symptoms

Individual Patient Expanded Access IND to Treat Polyneuropathy

Measuring the Amount of Methadone or Morphine in the Blood of Neonates, Infants & Children After Cardiac Surgery.

Limiting Trunk Flexion as a Self-treatment for Low Back Pain

The Women's Urology Center/WISH Database Project

A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain

MDMA-assisted Therapy for Fibromyalgia

ESP Blocks for Posterior Spinal Fusion

Group intEgrative MINdfulness Over the Internet Using an Online Platform

Magnetic Resonance Elastography of Myofascial Pain Syndrome

Study of Lornoxicam or Ketorolac or Placebo for Post-Operative Pain After Bunionectomy

Personalized Prediction of Persistent Postsurgical Pain

Virtual Reality Analgesia for Pediatric Burn Survivors

Effectiveness Study of Different Local Anesthetic Mixtures

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Effects of Spinal Cord Stimulation on Sensory Perceptions of Chronic Pain Patients

Bioequivalency Study of Amlodipine Tablets Under Fed Conditions

Self-Administered Acupressure for Veterans With Chronic Back Pain

Exercise Effect on Chemotherapy-Induced Neuropathic Pain

The Effect of Low Level Laser Therapy on Neck and Shoulder Pain

Cohort 2 (Abdominoplasty) of: A Multi-surgery Assessment of ZYNRELEF (HTX-011)

Phase 2 Chronic Low Back Pain Study

Digital Home-Exercise Therapy Application For Patients With Non-Surgical Knee Injuries

Oral Curcumin for the Treatment of Pain of Thumb Base Joint (CMC) Arthritis