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ClinicalTrials.gov public records Last synced Sep 3, 2026, 2:34 PM EDT

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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Pacemaker Malfunction Clear all
Terminated Phase 3 Interventional Results available

AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study

NCT00589303
View directory record Official record
Conditions
Atrial Fibrillation, Heart Failure
Interventions
FDA approved rate and rhythm control drugs, AV Node ablation and device implant
Drug · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
65 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
5
States / cities
Scottsdale, Arizona • Evansville, Indiana • Rochester, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2013 · Synced Sep 3, 2026, 2:34 PM EDT
Terminated Phase 4 Interventional

HEAL-HF: A Cardiac Resynchronization Therapy (CRT) Outcomes Study

NCT00370526
View directory record Official record
Conditions
Heart Failure, Congestive
Interventions
Acute hemodynamic assessment using PV Loops (CD Leycom, The Netherlands) during LV lead placement
Procedure
Lead sponsor
Stereotaxis
Industry
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
3
States / cities
Gainesville, Georgia • Charleston, South Carolina • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 10, 2008 · Synced Sep 3, 2026, 2:34 PM EDT
Terminated No phase listed Observational Results available

Arrythmia Burden in Cardiac Contractility Modulation (CCM)

NCT05704426
View directory record Official record
Conditions
Atrial Fibrillation, Arrythmia
Interventions
Impulse Dynamics Optimizer Device
Device
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced Sep 3, 2026, 2:34 PM EDT
Completed Not applicable Interventional Results available

RF Surgical Sponge-Detecting System on the Function of Pacemakers and Implantable Cardioverter Defibrillators

NCT02111980
View directory record Official record
Conditions
Cardiomyopathy, Cardiac Arrhythmia, Heart Failure, Chronic Thromboembolic Pulmonary Hypertension
Interventions
RF Assure Scanning
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Dec 23, 2019 · Synced Sep 3, 2026, 2:34 PM EDT
Completed No phase listed Observational

Use of Defibrillator Information in the Emergency Department

NCT00708058
View directory record Official record
Conditions
Congestive Heart Failure, Medical Device
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 19, 2012 · Synced Sep 3, 2026, 2:34 PM EDT
Withdrawn Phase 4 Interventional

Remote Interrogation in Rural Emergency Departments

NCT02421549
View directory record Official record
Conditions
Heart Disease, Cardiovascular Disease, Heart Failure, Arrhythmias, Cardiac
Interventions
Unpaired remote monitoring transmitter
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Sep 3, 2026, 2:34 PM EDT
Completed No phase listed Observational

Observational Study of ICD and Pacemaker Sensing in the Presence of IMED-4 Operation

NCT02191696
View directory record Official record
Conditions
Heart Failure
Interventions
IMED-4 recording
Device
Lead sponsor
Intersection Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Encinitas, California • Palm Springs, California
Source: ClinicalTrials.gov public record
Updated Jan 29, 2015 · Synced Sep 3, 2026, 2:34 PM EDT
Completed Not applicable Interventional

PITA-HF: Feasibility, Safety, and Tolerability

NCT04159454
View directory record Official record
Conditions
Heart Failure, Dilated Cardiomyopathy
Interventions
PITA
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Sep 3, 2026, 2:34 PM EDT
Completed No phase listed Observational

PROSPECT: Predictors of Response to Cardiac Re-Synchronization Therapy

NCT00253357
View directory record Official record
Conditions
Heart Failure, Congestive Heart Failure, Cardiomyopathy
Interventions
Not listed
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
16
States / cities
Several Locations, California • Gainsville, Florida • Atlanta, Georgia + 13 more
Source: ClinicalTrials.gov public record
Updated Dec 20, 2007 · Synced Sep 3, 2026, 2:34 PM EDT
Completed Not applicable Interventional Results available

Efficacy Study of Pacemakers to Treat Slow Heart Rate in Patients With Heart Failure

NCT02145351
View directory record Official record
Conditions
Heart Failure With a Preserved Ejection Fraction, Heart Failure, Diastolic, Chronotropic Incompetence
Interventions
Rate adaptive atrial pacing using a dual-chamber pacemaker, Pacemaker system will be implanted but set to Pacing Off.
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Sep 3, 2026, 2:34 PM EDT
Completed Not applicable Interventional Results available

Biventricular Versus Right Ventricular Pacing in Heart Failure Patients With Atrioventricular Block (BLOCK HF)

NCT00267098
View directory record Official record
Conditions
Atrioventricular Block, Heart Diseases
Interventions
Cardiac Resynchronization Therapy (CRT)
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
918 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2013
U.S. locations
51
States / cities
Anchorage, Alaska • Peoria, Arizona • Little Rock, Arkansas + 48 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2014 · Synced Sep 3, 2026, 2:34 PM EDT
Completed Not applicable Interventional Results available

Intravascular Ultrasound (IVUS) Imaging During Transvenous Lead Extraction

NCT04055740
View directory record Official record
Conditions
Device Malfunction, ICD, Pacemaker Lead Dysfunction
Interventions
IVUS Imaging
Device
Lead sponsor
University of Chicago
Other
Eligibility
21 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 2, 2024 · Synced Sep 3, 2026, 2:34 PM EDT
Completed Not applicable Interventional Results available

Effect of Chronic Changes in Heart Rate on Congestive Heart Failure

NCT00389649
View directory record Official record
Conditions
Heart Failure, Congestive
Interventions
heart rate setting
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 19, 2021 · Synced Sep 3, 2026, 2:34 PM EDT
Terminated No phase listed Observational Results available

OMNI Study--Assessing Therapies in Medtronic Pacemaker, Defibrillator, and Cardiac Resynchronization Therapy Devices.

NCT00277524
View directory record Official record
Conditions
Tachycardia, Ventricular, Heart Failure, Congestive, Ventricular Fibrillation, Ventricular Dysfunction, Bradycardia
Interventions
Not listed
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
3,032 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
113
States / cities
Tucson, Arizona • Little Rock, Arkansas • Fresno, California + 107 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2013 · Synced Sep 3, 2026, 2:34 PM EDT
Withdrawn Not applicable Interventional

The Effect of Yoga on Cardiac Sympathetic Innervation Evaluated by I-123 mIBG

NCT03227393
View directory record Official record
Conditions
Heart Failure, Systolic
Interventions
Yoga training
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 19, 2018 · Synced Sep 3, 2026, 2:34 PM EDT
Completed Not applicable Interventional

Personalized Pacing: A New Paradigm for Patients With Diastolic Dysfunction or Heart Failure With Preserved Ejection Fraction

NCT04721314
View directory record Official record
Conditions
Pacemaker, Diastolic Dysfunction, Diastolic Heart Failure
Interventions
Adjustment of lower rate limit, Maintenance of lower rate limit
Device
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 8, 2022 · Synced Sep 3, 2026, 2:34 PM EDT
Completed No phase listed Observational

LV Dysfunction Following Pacemaker Placement

NCT03850808
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 24, 2019 · Synced Sep 3, 2026, 2:34 PM EDT
Completed No phase listed Observational

Optivol Diagnostic Data for Discharge in Heart Failure

NCT00420108
View directory record Official record
Conditions
Heart Failure, Congestive, Cardiac Pacemaker, Artificial
Interventions
Not listed
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
5
States / cities
Saint Joseph, Missouri • Elmer, New Jersey • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2010 · Synced Sep 3, 2026, 2:34 PM EDT
Completed No phase listed Observational

TRENDS: A Prospective Study of the Clinical Significance of Atrial Arrhythmias Detected by Implanted Device Diagnostics

NCT00279981
View directory record Official record
Conditions
Atrial Fibrillation, Stroke, Heart Failure
Interventions
Diagnostic
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
3,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
92
States / cities
Mesa, Arizona • Tucson, Arizona • Fountain Valley, California + 89 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2008 · Synced Sep 3, 2026, 2:34 PM EDT
Completed Not applicable Interventional Results available

Cardiac Resynchronization in the Elderly

NCT03031847
View directory record Official record
Conditions
Heart Failure
Interventions
Cardiac Resynchronization Therapy Pacemaker, Cardiac Resynchronization Therapy Defibrillator
Device
Lead sponsor
Samir Saba
Other
Eligibility
75 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
6
States / cities
Durham, North Carolina • Columbus, Ohio • Erie, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Sep 3, 2026, 2:34 PM EDT
Recruiting No phase listed Observational

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

NCT00271180
View directory record Official record
Conditions
Arrhythmia, Bradycardia, Heart Failure, Sinus Tachycardia
Interventions
Device
Device
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1983 – 2040
U.S. locations
113
States / cities
Birmingham, Alabama • Anchorage, Alaska • Chandler, Arizona + 110 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 3, 2026, 2:34 PM EDT
Completed No phase listed Observational Results available

Pacemaker Therapy in Adults With Congenital Heart Defects

NCT00303511
View directory record Official record
Conditions
Congenital Disorder
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
19 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2006
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 7, 2014 · Synced Sep 3, 2026, 2:34 PM EDT
Completed No phase listed Observational

Necklace-Shaped Sensor for Non-Invasive Remote Monitoring of Vitals

NCT02337790
View directory record Official record
Conditions
Heart Failure, Hypertension
Interventions
Not listed
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years to 90 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Imperial, California
Source: ClinicalTrials.gov public record
Updated Dec 29, 2015 · Synced Sep 3, 2026, 2:34 PM EDT
Terminated Not applicable Interventional Results available

Investigational Device Exemption (IDE) Study for the Approval of Closed Loop Stimulation (CLS) and Cardiac Resyncronization Pacing Therapies (CRT) for the Treatment of Atrial Fibrillation (AF) With Ablate and Pace

NCT00356057
View directory record Official record
Conditions
Atrial Fibrillation, Congestive Heart Failure
Interventions
Protos DR/CLS and Stratos LV CRT pacemakers
Device
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
10
States / cities
Birmingham, Alabama • Lake Charles, Louisiana • Boston, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2018 · Synced Sep 3, 2026, 2:34 PM EDT