- Conditions
- Chronic Knee Pain
- Interventions
- Photobiomodulation therapy (PBM) device, Sham PBM device
- Device
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 50 Years to 99 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Osteoarthritis, Knee
- Interventions
- Genicular nerve radiofrequency ablation, Pain Management Radiofrequency Kit
- Procedure · Device
- Lead sponsor
- Millennium Pain Center
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 79 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 3
- States / cities
- Bloomington, Illinois • Decatur, Illinois • Peoria, Illinois
- Conditions
- Osteoarthritis
- Interventions
- Canakinumab, Placebo to canakinumab, Naproxen, Placebo to Naproxen
- Biological · Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 169 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 8
- States / cities
- Anniston, Alabama • Mesa, Arizona • San Diego, California + 5 more
- Conditions
- Osteoarthritis
- Interventions
- External Qigong therapy
- Procedure
- Lead sponsor
- National Center for Complementary and Integrative Health (NCCIH)
- NIH
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 2
- States / cities
- Newark, New Jersey • Piscataway, New Jersey
- Conditions
- Arthroplasty, Replacement, Knee, Pain, Postoperative
- Interventions
- Adductor Canal Block, Adductor Canal Block
- Procedure · Drug
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 1
- States / cities
- Madison, Wisconsin
- Conditions
- Total Knee Athroplasty
- Interventions
- Periarticular Injection (PAI), Saline Control Periarticular Injection (PAI)
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 25 Years to 80 Years
- Enrollment
- 94 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis of the Knee
- Interventions
- ABT-652, Placebo, Naproxen
- Drug
- Lead sponsor
- AbbVie (prior sponsor, Abbott)
- Industry
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 322 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 23
- States / cities
- Chandler, Arizona • Tempe, Arizona • Tucson, Arizona + 20 more
- Conditions
- Peripheral Arterial Disease Below the Knee, Peripheral Arterial Disease, Rutherford 4 and 5 with Possibility to Improve Vascularization
- Interventions
- Multicath, Standard of Care (SOC)
- Device
- Lead sponsor
- Summa Therapeutics, LLC
- Industry
- Eligibility
- 18 Years to 120 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 2
- States / cities
- Wilmington, Delaware • Vineland, New Jersey
- Conditions
- Arthritis Knee, Knee Osteoarthritis, Pain, Postoperative
- Interventions
- Methylprednisolone 4 milligram Tab, Dexamethasone injection
- Drug
- Lead sponsor
- F. Johannes Plate
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 2
- States / cities
- Monroeville, Pennsylvania • Pittsburgh, Pennsylvania
- Conditions
- Knee Osteoarthritis
- Interventions
- Noxious Electrical Stimulation (NxES)
- Device
- Lead sponsor
- University of New England
- Other
- Eligibility
- 50 Years to 90 Years
- Enrollment
- 13 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Portland, Maine
- Conditions
- Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of the Knee, Avascular Necrosis, Patellofemoral Osteoarthritis
- Interventions
- Zimmer Biomet Persona Ti-Nidium Total Knee System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2034
- U.S. locations
- 7
- States / cities
- Parker, Colorado • Hyattsville, Maryland • Jackson, Mississippi + 4 more
- Conditions
- Osteoarthritis of the Knee
- Interventions
- FX006, Placebo, TCA IR 40
- Drug
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 486 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 22
- States / cities
- Phoenix, Arizona • Tucson, Arizona • Anaheim, California + 17 more
- Conditions
- Osteoarthritis, Knee, Pain, Physical Activity, Mitochondrial Pathology
- Interventions
- Walking
- Behavioral
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 50 Years to 80 Years
- Enrollment
- 13 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Osteoarthritis
- Interventions
- NEM, Placebo
- Dietary Supplement
- Lead sponsor
- ESM Technologies, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 67 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2006
- U.S. locations
- 3
- States / cities
- Cuba, Missouri • Kirksville, Missouri • Springfield, Missouri
- Conditions
- Post-surgical Pain, Total Knee Arthroplasty, Foot/Ankle Surgery, Catheterization for Postop Analgesia
- Interventions
- ropivacaine 0.2%
- Drug
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 117 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Cartilage Injury, Knee Injuries, Arthropathy of Knee, Cartilage Damage, Knee Pain Swelling
- Interventions
- 7 Tesla Magnetic Resonance Imaging Test
- Diagnostic Test
- Lead sponsor
- The Methodist Hospital Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 112 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Knee Osteoarthritis, Mind-body Exercise
- Interventions
- Tai chi exercise
- Behavioral
- Lead sponsor
- Texas Tech University Health Sciences Center
- Other
- Eligibility
- Female only
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 1
- States / cities
- Lubbock, Texas
- Conditions
- Postoperative Pain
- Interventions
- Nerve block
- Procedure
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 21 Years to 80 Years
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Primary Total Knee Arthroplasty, Intraosseous Morphine Injection, Knee Osteoarthritis
- Interventions
- Morphine, Vancomycin
- Drug
- Lead sponsor
- Carilion Clinic
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Roanoke, Virginia
- Conditions
- Knee Osteoarthritis
- Interventions
- Corticosteroid injection
- Drug
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Arthropathy of Knee Joint
- Interventions
- Not listed
- Lead sponsor
- Trinity Health Of New England
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Hartford, Connecticut
- Conditions
- Osteoarthritis, Knee
- Interventions
- Traumeel® / Zeel® Injectable Solution, Placebo
- Drug
- Lead sponsor
- Biologische Heilmittel Heel GmbH
- Industry
- Eligibility
- 45 Years to 80 Years
- Enrollment
- 287 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 30
- States / cities
- Phoenix, Arizona • Tucson, Arizona • Dinuba, California + 24 more
- Conditions
- Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
- Interventions
- Dry Needling, Sham Dry Needling, Physical Therapy
- Device · Other
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2030
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Knee Osteoarthritis, Post-traumatic Osteoarthritis
- Interventions
- Unicompartmental Biologic Arthroplasty, Extensive Biologic Arthroplasty
- Procedure
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Columbia, Missouri