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ClinicalTrials.gov public records Last synced Oct 25, 2026, 11:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 625–648 of 10,279 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pain Clear all
Completed Not applicable Interventional

S1200: Acupuncture, Sham Acupuncture, or Wait List for Joint Symptoms Related to Aromatase Inhibitors in Pts W/Early-Stage Breast Cancer

NCT01535066
View directory record Official record
Conditions
Breast Cancer, Pain
Interventions
acupuncture therapy, sham acupuncture
Procedure
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
18 Years and older · Female only
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
47
States / cities
Antioch, California • Fremont, California • Los Angeles, California + 36 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Oct 25, 2026, 11:19 AM EDT
Completed Not applicable Interventional

Virtual Reality at End-of-life

NCT06149429
View directory record Official record
Conditions
End of Life, Pain, Nausea, Fatigue, Well-Being, Psychological, Depression, Dyspnea, Appetite Loss, Anxiety
Interventions
Personalized virtual reality experience
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
Not listed
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cheektowaga, New York
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Oct 25, 2026, 11:19 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Using MRI Scans to Evaluate Spinal Manipulation

NCT00070902
View directory record Official record
Conditions
Lower Back Pain
Interventions
Lumbar side-posture spinal adjusting
Procedure
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
21 Years to 29 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2002
U.S. locations
1
States / cities
Lombard, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 18, 2006 · Synced Oct 25, 2026, 11:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Transcranial Direct Current Stimulation (tDCS) in Chronic Corneal Pain

NCT01575002
View directory record Official record
Conditions
Corneal Pain, Chronic Pain, Neuropathic Pain
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 25, 2026, 11:19 AM EDT
Completed Phase 3 Interventional Results available

Maxigesic 325 Acute Dental Pain Study

NCT01420653
View directory record Official record
Conditions
Dental Pain
Interventions
Maxigesic 325, Acetaminophen, Ibuprofen, Placebo
Drug
Lead sponsor
AFT Pharmaceuticals, Ltd.
Industry
Eligibility
18 Years to 60 Years
Enrollment
408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 6, 2018 · Synced Oct 25, 2026, 11:19 AM EDT
Not yet recruiting Phase 2 Interventional Accepts healthy volunteers

Long Duration High Frequency Ultrasound for the Treatment of Osteoarthritis

NCT07515872
View directory record Official record
Conditions
Arthritis, Osteo Arthritis of the Knee
Interventions
Sustained Acoustic Device with 2.5% Diclofenac Patch, Sustained Acoustic Device with 0% Diclofenac Patch, Intra articular injection
Device · Drug
Lead sponsor
ZetrOZ, Inc.
Industry
Eligibility
65 Years to 85 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
Stamford, Connecticut • Dryden, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 25, 2026, 11:19 AM EDT
Recruiting Early Phase 1 Interventional

A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

NCT06906939
View directory record Official record
Conditions
Knee Osteoarthritis, Depression
Interventions
repetetive transcranial magnetic stimulation
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years to 95 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 25, 2026, 11:19 AM EDT
Terminated Phase 2 Interventional Results available

Effect of Febuxostat Compared to Placebo on Exercise Tolerance in Participants With Chronic Stable Angina

NCT01549977
View directory record Official record
Conditions
Angina
Interventions
Febuxostat, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 85 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
21
States / cities
Carmichael, California • Fresno, California • Irvine, California + 18 more
Source: ClinicalTrials.gov public record
Updated Dec 20, 2013 · Synced Oct 25, 2026, 11:19 AM EDT
Completed Not applicable Interventional

Acupuncture for the Treatment of Vulvodynia

NCT02197429
View directory record Official record
Conditions
Vulvodynia, Vulvar Vestibulitis, Pain, Dyspareunia, Female Sexual Dysfunction Due to Physical Condition
Interventions
Acupuncture
Other
Lead sponsor
Schlaeger, Judith M., CNM, LAc, PhD
Individual
Eligibility
18 Years and older · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Glenview, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 22, 2014 · Synced Oct 25, 2026, 11:19 AM EDT
Active, not recruiting Not applicable Interventional

Cordotomy in Reducing Pain in Patients With Advanced Cancer

NCT04119037
View directory record Official record
Conditions
Advanced Malignant Neoplasm
Interventions
Cordotomy, Morphine, Questionnaire Administration, Sham Intervention
Procedure · Drug · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 25, 2026, 11:19 AM EDT
Completed Not applicable Interventional Results available

LED Therapy for the Treatment of Concussive Brain Injury

NCT02383472
View directory record Official record
Conditions
Brain Concussion
Interventions
MedX Health Console model 1100, MedX Health Console model 1100-placebo
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
11 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 26, 2018 · Synced Oct 25, 2026, 11:19 AM EDT
Completed Phase 2 Interventional Results available

NSAID Effects on Clinical and Imaging Breast Biomarkers

NCT01761877
View directory record Official record
Conditions
Inflammation, Cancer, Pain, Hypertension
Interventions
Sulindac
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
Up to 75 Years · Female only
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
2
States / cities
Tucson, Arizona • Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Feb 10, 2023 · Synced Oct 25, 2026, 11:19 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Randomized Trial of Wound Infiltration With Extended-release Bupivacaine Before Laparoscopic or Robotic Hysterectomy

NCT02352922
View directory record Official record
Conditions
Pain, Postoperative, Surgical Procedure, Unspecified
Interventions
Liposomal Bupivacaine, Bupivacaine HCl
Drug
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Oct 1, 2020 · Synced Oct 25, 2026, 11:19 AM EDT
Completed Not applicable Interventional Results available

Initial Testing of a Mobile App Pain Coping Intervention for Outpatient Oncology Settings (PainPac)

NCT05686122
View directory record Official record
Conditions
Colorectal Cancer
Interventions
PainPac
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Oct 25, 2026, 11:19 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Evaluation of the Analgesic Efficacy of Multimodal Pain Control Regimens That Aim to Limit the Use of Narcotics in Cholecystectomy and Hernia Repairs

NCT06095453
View directory record Official record
Conditions
Acute Pain
Interventions
Pain control regimens
Other
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2024 · Synced Oct 25, 2026, 11:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Heat Wrap Device Safety With Age and Body Fat

NCT01355653
View directory record Official record
Conditions
Back Pain
Interventions
thermal therapy, ThermaCare heatwrap
Device
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 84 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Oct 25, 2026, 11:19 AM EDT
Recruiting Phase 3 Interventional

R.E.C.K vs Exparel in Robotic Nephrectomy

NCT07092566
View directory record Official record
Conditions
Renal Carcinoma, Nephrectomy / Methods, Pain Management
Interventions
Ropivacaine HCL, Exparel, Epinephrine, Clonidine HCL, Ketorolac
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 25, 2026, 11:19 AM EDT
Recruiting Phase 1 Interventional

A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain

NCT07447856
View directory record Official record
Conditions
Cancer Patients, Survivor Patients, Cancer Pain
Interventions
Topical herbal plaster
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 25, 2026, 11:19 AM EDT
Completed No phase listed Observational

PNE Delivered With a VR Headset in Outpatient LBP Patients

NCT04777877
View directory record Official record
Conditions
Chronic Pain
Interventions
Pain Neuroscience Education delivered via a Virtual Reality Headset
Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Oct 25, 2026, 11:19 AM EDT
Not yet recruiting Phase 2 Interventional

A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder

NCT06710431
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Abuse/addiction, Anxiety, Pain Threshold, Depression Disorders, Sleep Disorder
Interventions
AFA-281
Drug
Lead sponsor
Afasci Inc
Industry
Eligibility
21 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 25, 2026, 11:19 AM EDT
Recruiting Not applicable Interventional

The Benefits Of Cryoablation In Patients Undergoing Total Knee Arthroplasty

NCT06991231
View directory record Official record
Conditions
Post-Operative Pain, Total Knee Arthroplasty
Interventions
Total knee arthroplasty (TKA), Cryoablation
Procedure · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 25, 2026, 11:19 AM EDT
Completed Not applicable Interventional

Effect of Knee Bracing on Improving Pain & Disability

NCT04044612
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Medial Unloader Brace
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
40 Years to 75 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 8, 2021 · Synced Oct 25, 2026, 11:19 AM EDT
Completed Not applicable Interventional Results available

Mechanistic Studies on Video-guided Acupuncture Imagery Treatment of Knee Pain

NCT03261505
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Acupuncture
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
40 Years to 70 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 25, 2026, 11:19 AM EDT
Completed Phase 2 Interventional

Fibromyalgia Outcome Research Trial Evaluating Synergistic Suppression of HSV-1

NCT04748705
View directory record Official record
Conditions
Fibromyalgia
Interventions
IMC-1, Placebo BID Tablet
Drug
Lead sponsor
Virios Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
42
States / cities
Birmingham, Alabama • Rogers, Arkansas • Oceanside, California + 39 more
Source: ClinicalTrials.gov public record
Updated Sep 27, 2022 · Synced Oct 25, 2026, 11:19 AM EDT