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ClinicalTrials.gov public records Last synced Oct 27, 2026, 1:10 PM EDT

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Showing 913–936 of 10,287 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pain Clear all
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Vasopressin and Pain Perception in the Brain

NCT03446456
View directory record Official record
Conditions
Acute Pain
Interventions
Arginine vasopressin, Saline, Observational learning, fMRI data aquisition
Drug · Other · Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Phase 3 Interventional Results available

A Study To Evaluate The Efficacy And Safety Of TNX-102 SL In Patients With Fibromyalgia

NCT04172831
View directory record Official record
Conditions
Fibromyalgia
Interventions
TNX-102 SL, Placebo SL Tablet
Drug
Lead sponsor
Tonix Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
503 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
39
States / cities
Birmingham, Alabama • Phoenix, Arizona • Oceanside, California + 36 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Not applicable Interventional Results available

Video-based, Patient-Focused Opioid Education in the Perioperative Period

NCT03986866
View directory record Official record
Conditions
Opioid Use, Chronic Pain Post-Procedural
Interventions
Video
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Oct 27, 2026, 1:10 PM EDT
Recruiting Phase 3 Interventional

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

NCT07353931
View directory record Official record
Conditions
Osteoarthritis, Overweight or Obesity
Interventions
Eloralintide, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
39
States / cities
Mobile, Alabama • Mesa, Arizona • Phoenix, Arizona + 34 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Phase 2 Interventional

A Pilot Study on the Onset of Action of KTP, 20% in the Treatment of Acute Pain Associated With Tendonitis or Bursitis of the Shoulder, Elbow or Knee

NCT00903994
View directory record Official record
Conditions
Tendonitis of the Shoulder, Elbow, or Knee
Interventions
Ketoprofen Topical Patch 20%
Drug
Lead sponsor
APR Applied Pharma Research s.a.
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
2
States / cities
Phoenix, Arizona • Stockbridge, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 18, 2020 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Phase 2 Interventional

Mind-Body Therapy for Pain in Ehlers-Danlos Syndrome

NCT00001966
View directory record Official record
Conditions
Ehlers-Danlos Syndrome, Pain
Interventions
Mind-body therapy
Drug
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Phase 2 Interventional Results available

Chronic Pain Master Protocol (CPMP): A Study of LY3526318 in Participants With Diabetic Peripheral Neuropathic Pain

NCT05177094
View directory record Official record
Conditions
Diabetic Peripheral Neuropathic Pain
Interventions
LY3526318, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
35
States / cities
Chandler, Arizona • Glendale, Arizona • Phoenix, Arizona + 28 more
Source: ClinicalTrials.gov public record
Updated Nov 22, 2023 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Not applicable Interventional Results available

A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Acute Pain Trial)

NCT05966129
View directory record Official record
Conditions
Acute Pain
Interventions
Pharmacogenetic testing, Clinical decisions support
Other
Lead sponsor
Duke University
Other
Eligibility
8 Years and older
Enrollment
1,602 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
11
States / cities
Wilmington, Delaware • Gainesville, Florida • Jacksonville, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Not applicable Interventional

Acceptance and Commitment Therapy for Chronic Pain in SCI: Development and Testing of an eHealth Program

NCT06098170
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Unguided use of the My SCI Toolkit program, Coached My SCI Toolkit
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Phase 2 Interventional Results available

Inhaled Mometasone to Reduce Painful Episodes in Patients With Sickle Cell Disease

NCT02061202
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Mometasone Furoate, Placebo
Drug
Lead sponsor
Jeffrey Glassberg
Other
Eligibility
15 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 11, 2019 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Not applicable Interventional

Patient Education for Patients With Back Pain Referred to Physical Therapy

NCT02648373
View directory record Official record
Conditions
Low Back Pain
Interventions
Patient Education, Control
Behavioral · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 7, 2016 · Synced Oct 27, 2026, 1:10 PM EDT
Enrolling by invitation Not applicable Interventional

Use of Simplified Pain Questionnaire Among People Receiving Anterior Cruciate Ligament (ACL) Knee Surgery?

NCT07065266
View directory record Official record
Conditions
Anterior Cruciate Ligament (ACL) Reconstruction, Anterior Cruciate Ligament/Surgery
Interventions
Binary pain questionnaire, Numerical Pain Rating Scale (NPRS)
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Phase 4 Interventional

Prospective, Randomized, Multi-center Clinical Study of Plasma Disc Decompression

NCT00189605
View directory record Official record
Conditions
Radicular Pain
Interventions
Perc-DLR/Perc-DLG, Fluoroscopy guided transforaminal epidural steroid injection (TFESI)
Device · Drug
Lead sponsor
ArthroCare Corporation
Other
Eligibility
18 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
13
States / cities
Scottsdale, Arizona • Little Rock, Arkansas • Napa, California + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2015 · Synced Oct 27, 2026, 1:10 PM EDT
Active, not recruiting Not applicable Interventional Results available

Optimizing Rehabilitation for Phantom Limb Pain Using Mirror Therapy and Transcranial Direct Current Stimulation (tDCS)

NCT02487966
View directory record Official record
Conditions
Phantom Limb Pain, Amputation, Traumatic
Interventions
transcranial Direct Current Stimulation (tDCS): active (Soterix ©), Mirror Therapy: active, transcranial Direct Current Stimulation (tDCS): sham (Soterix ©), Mirror Therapy: Sham
Device · Behavioral
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Not applicable Interventional

Randomized Clinical Trial of Rehabilitation for Subacromial Impingement Syndrome

NCT00633451
View directory record Official record
Conditions
Shoulder Impingement Syndrome
Interventions
Manual Therapy and Exercise, Exercise Only
Other
Lead sponsor
Proaxis Therapy
Industry
Eligibility
18 Years to 75 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 28, 2013 · Synced Oct 27, 2026, 1:10 PM EDT
Active, not recruiting Not applicable Interventional

Structured Post-Operative Pain and Distress Treatment Intervention for Patients Undergoing Surgery for Intra-Abdominal Malignancies

NCT06858202
View directory record Official record
Conditions
Psychological Distress, Intra-abdominal Cancer
Interventions
Mindfulness Intervention, Non-mindfulness Intervention
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 27, 2026, 1:10 PM EDT
Completed No phase listed Observational

Psychometric Evaluation of the IPPAQ in Pediatric Patients With Sickle Cell Disease Hospitalized With Vasoocclusive Pain

NCT01058473
View directory record Official record
Conditions
Sickle Cell Disease, Pain
Interventions
Not listed
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
7 Years to 21 Years
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 30, 2013 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Phase 3 Interventional

A Study to Evaluate a Fixed Combination of Acetaminophen/Naproxen Sodium in Acute Postoperative Pain Following Bunionectomy

NCT05868122
View directory record Official record
Conditions
Pain
Interventions
Acetaminophen/Naproxen Sodium Fixed Combination, Placebo
Drug
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
16 Years to 65 Years
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
4
States / cities
New Providence, New Jersey • Bellaire, Texas • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 27, 2026, 1:10 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

BreEStim Pre-trial

NCT07878429
View directory record Official record
Conditions
Neuropathic Pain
Interventions
Single-pulse BreEStim Treatment, Multiple-pulse BreEStim Treatment
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Not applicable Interventional

Brief Nurse-led Mindfulness Based Intervention

NCT04800354
View directory record Official record
Conditions
Pain, Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions
Nurse-led Mindfulness Based Intervention, Nurse-led Pain Psychoeducation
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 11, 2022 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Not applicable Interventional Results available

An Evaluation of MBSR and CBT for Veterans With Chronic Pain

NCT04486066
View directory record Official record
Conditions
Chronic Pain, Pain
Interventions
Mindfulness-Based Stress Reduction, Cognitive Behavioral Therapy for Chronic Pain, Usual Care
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Oct 27, 2026, 1:10 PM EDT
Not listed Not applicable Interventional

Transcranial Direct Current Stimulation and Chronic Pain

NCT05863494
View directory record Official record
Conditions
Chronic Pain
Interventions
Transcranial Direct Current Stimulation (tDCS), Transcranial Direct Current Stimulation (tDCS) sham
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 79 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Not applicable Interventional

Prometra Post-Approval Study

NCT01854229
View directory record Official record
Conditions
Chronic Pain, Cancer Pain, Intractable Pain, Back Pain
Interventions
Prometra Programmable Intrathecal Infusion Pump
Device
Lead sponsor
Flowonix Medical
Industry
Eligibility
22 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
26
States / cities
La Jolla, California • Santa Barbara, California • Santa Rosa, California + 20 more
Source: ClinicalTrials.gov public record
Updated Oct 18, 2023 · Synced Oct 27, 2026, 1:10 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pre-incision Versus Post-incision Local Anesthetic During Robotic Sacrocolpopexy

NCT04996251
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Bupivacaine Injection
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older · Female only
Enrollment
129 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Oct 27, 2026, 1:10 PM EDT