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ClinicalTrials.gov public records Last synced Oct 28, 2026, 10:23 AM EDT

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Showing 49–72 of 129 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Pain Levels Clear all
Terminated Phase 4 Interventional Results available

Esmolol Infusion During Laminectomy: Effect on Quality of Recovery

NCT01179113
View directory record Official record
Conditions
Laminectomy
Interventions
Esmolol, Saline
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 2, 2016 · Synced Oct 28, 2026, 10:23 AM EDT
Terminated Not applicable Interventional

Low Level Laser Therapy (LLLT) for the Treatment of Hand Osteoarthritis.

NCT04692597
View directory record Official record
Conditions
Low Level Laser Therapy, Osteoarthritis, Family Medicine, Pain Management, Integrative Medicine
Interventions
Phoenix Thera-Lase System, SHAM Phoenix Thera-Lase System
Device
Lead sponsor
David Moss
Federal
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Nellis Air Force Base, Nevada
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Oct 28, 2026, 10:23 AM EDT
Not listed No phase listed Observational

The Nociception Level During General Anesthesia

NCT01978379
View directory record Official record
Conditions
Pain
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 13, 2014 · Synced Oct 28, 2026, 10:23 AM EDT
Withdrawn Not applicable Interventional

Study of the Acute Effects of Guided Imagery and tDCS on Pain Levels in Women With Chronic Pelvic Pain

NCT04250662
View directory record Official record
Conditions
Pelvic Pain, Chronic Pain
Interventions
Active tDCS with guided imagery, Active tDCS alone (no guided imagery), Sham tDCS with guided imagery, Sham tDCS alone (no guided imagery)
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 64 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 23, 2022 · Synced Oct 28, 2026, 10:23 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

RHA® Redensity With New Anesthetic Agent Perioral Rhytids (PAS)

NCT06378086
View directory record Official record
Conditions
Pain, Aging
Interventions
RHA® Redensity with new anesthetic agent, RHA® Redensity with lidocaine
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Birmingham, Alabama • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 11, 2025 · Synced Oct 28, 2026, 10:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Methylglyoxal Evaluation in Humans

NCT05350553
View directory record Official record
Conditions
Type 2 Diabetes, Neuropathy, Painful, Chronic Low-back Pain, Lumbar Disc Herniation
Interventions
Not listed
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
45 Years to 75 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 28, 2026, 10:23 AM EDT
Completed Phase 4 Interventional

Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis

NCT00000409
View directory record Official record
Conditions
Spondylolisthesis, Spinal Stenosis, Low Back Pain
Interventions
Decompressive laminectomy, Non-surgical treatments, Fusion--Instrumented, Fusion-Non-instrumented
Procedure · Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2015
U.S. locations
13
States / cities
Oakland, California • San Francisco, California • Decatur, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Oct 28, 2026, 10:23 AM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate the Effect of Low Level Laser Light on Low Back Pain

NCT02538523
View directory record Official record
Conditions
Low Back Pain
Interventions
Erchonia FX-635, Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Chandler, Arizona • San Mateo, California • Bloomfield, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Oct 28, 2026, 10:23 AM EDT
Terminated Not applicable Interventional

Study of Emu Oil vs. Placebo for Vulvar Pain in Women.

NCT01295268
View directory record Official record
Conditions
Vulvodynia, Vestibulodynia
Interventions
Emu Oil, Inert oil
Other
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 25, 2017 · Synced Oct 28, 2026, 10:23 AM EDT
Completed Phase 3 Interventional

Safety and Efficacy of Dextromethorphan and Quinidine in the Treatment of the Pain of Diabetic Neuropathy

NCT00113620
View directory record Official record
Conditions
Pain, Diabetic Neuropathy
Interventions
Neurodex
Drug
Lead sponsor
Avanir Pharmaceuticals
Industry
Eligibility
18 Years to 80 Years
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
44
States / cities
Mesa, Arizona • Sun City, Arizona • Hot Springs, Arkansas + 39 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2016 · Synced Oct 28, 2026, 10:23 AM EDT
Completed Phase 2 Interventional Results available

A Study to Investigate Efficacy and Safety of OG-6219 BID in 3 Dose Levels Compared With Placebo in Participants Aged 18 to 49 With Moderate to Severe Endometriosis-related Pain

NCT05560646
View directory record Official record
Conditions
Endometriosis
Interventions
OG-6219, Placebo
Drug
Lead sponsor
Organon and Co
Industry
Eligibility
18 Years to 49 Years · Female only
Enrollment
354 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
27
States / cities
Birmingham, Alabama • Los Angeles, California • Orange, Connecticut + 22 more
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 28, 2026, 10:23 AM EDT
Withdrawn Phase 1Phase 2 Interventional

Isometric Intervention for Lateral Elbow Tendinopathy

NCT03756155
View directory record Official record
Conditions
Lateral Elbow Tendinopathy, Elbow Pain, Elbows Tendonitis, Elbow Sprain, Elbow Injury
Interventions
isometric intervention
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Oct 28, 2026, 10:23 AM EDT
Withdrawn Not applicable Interventional

Preoperative Corticosteroid Epidural Injection and Lumbar Decompression Surgery Outcomes

NCT03543033
View directory record Official record
Conditions
Lumbar Radiculopathy
Interventions
Corticosteroid injection
Drug
Lead sponsor
Lahey Clinic
Other
Eligibility
30 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 18, 2020 · Synced Oct 28, 2026, 10:23 AM EDT
Completed Not applicable Interventional

Does Distraction With a Hand Held Video Game Reduce Preoperative and Emergence Anxiety in Children?

NCT00932685
View directory record Official record
Conditions
Pediatric Emergence Agitation and Pain
Interventions
Midazolam, Game Boy
Drug · Device
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
4 Years to 12 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 3, 2009 · Synced Oct 28, 2026, 10:23 AM EDT
Recruiting Not applicable Interventional

Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery

NCT07218133
View directory record Official record
Conditions
Spinal Fusion, Hyperglycemia, Postoperative Pain Management, Postoperative Care, Spine Disease, Neurologic Deficits, Neurological Disorder, Inflammation, Spine Condition, Spinal (Fusion) Surgery, Cytokine Levels, Spine Fusion
Interventions
Auricular vagus nerve stimulation, Sham Auricular Vagus nerve Stimulation
Device
Lead sponsor
Alexander T. Yahanda
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 28, 2026, 10:23 AM EDT
Completed Phase 1 Interventional

Study to Evaluate the Safety and Preliminary Efficacy of IDCT, a Treatment for Symptomatic Lumbar Intervertebral Disc Degeneration

NCT03347708
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
IDCT, Saline Solution, Sodium Hyaluronate
Biological · Drug
Lead sponsor
DiscGenics, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
14
States / cities
Birmingham, Alabama • Los Angeles, California • San Diego, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Oct 28, 2026, 10:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of Cecal Intubation Rates and Pain Levels Between Water Exchange and Air Insufflation Flexible Sigmoidoscopy

NCT03209349
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Water Exchange Sigmoidoscopy, Air Insufflation Sigmoidoscopy
Procedure
Lead sponsor
Kelowna Gastroenterology Associates
Other
Eligibility
50 Years to 74 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Nov 7, 2022 · Synced Oct 28, 2026, 10:23 AM EDT
Active, not recruiting Not applicable Interventional

Spinal Cord Stimulation (SCS) for Spinal Cord Injury (SCI)

NCT04894734
View directory record Official record
Conditions
Spinal Cord Injury at T1-T12 Level, Traumatic Thoracic Spinal Cord Contusion, Thoracic Spinal Cord Trauma, Traumatic Thoracic Spinal Cord Laceration, Post-Traumatic Thoracic Myelopathy, Traumatic Thoracic Spinal Cord Myelopathy
Interventions
EES on, EES off
Device
Lead sponsor
Nandan Lad, M.D., Ph.D.
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 28, 2026, 10:23 AM EDT
Withdrawn No phase listed Observational

Real-Time Accurate Pathology Inspection and Decompression Study

NCT05347108
View directory record Official record
Conditions
Spine Injuries and Disorders, Pain, Chronic, Pain, Back, Pain, Neck, Radiculopathy
Interventions
laser-assisted neural decompression (LAND) procedure
Procedure
Lead sponsor
KM Clinical Research Group
Industry
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lā‘ie, Hawaii
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Oct 28, 2026, 10:23 AM EDT
Recruiting Not applicable Interventional

PerQdisc Traditional Feasibility Trial.

NCT06860867
View directory record Official record
Conditions
Discogenic Low Back Pain
Interventions
PerQdisc
Device
Lead sponsor
Spinal Stabilization Technologies
Industry
Eligibility
22 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
8
States / cities
Glendale, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 4 more
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 28, 2026, 10:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Hormonal Effects on Pain Perception

NCT00699595
View directory record Official record
Conditions
Pregnancy, Progesterone Levels, Pregnancy Associated Analgesia
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 45 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 11, 2014 · Synced Oct 28, 2026, 10:23 AM EDT
Not yet recruiting Not applicable Interventional

Ischemic Compression and Low-Level Laser Therapy for Myofascial Low Back Pain

NCT07832422
View directory record Official record
Conditions
Low Back Pain, Myofascial Pain Syndromes
Interventions
Ischemic Compression, Low-Level Laser Therapy, Exercise Program, Sham Low-Level Laser Therapy
Other · Device
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 28, 2026, 10:23 AM EDT
Recruiting Not applicable Interventional

Contrast and Anesthetic Level With Lumbar Erector Spinae Plan (ESP) Block

NCT07174440
View directory record Official record
Conditions
Pain
Interventions
Ropivacaine (Epidural analgesia), Dexmedetomidine, Iohexol, QST Procedure
Drug · Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
21 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 28, 2026, 10:23 AM EDT
Terminated Not applicable Interventional Results available

An Evaluation of the Effect of Low Level Laser Therapy on Diabetic Peripheral Neuropathy Pain

NCT04006392
View directory record Official record
Conditions
Diabetic Peripheral Neuropathy
Interventions
Erchonia FX-635, Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
4
States / cities
Mesa, Arizona • Costa Mesa, California • Hialeah, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2023 · Synced Oct 28, 2026, 10:23 AM EDT