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ClinicalTrials.gov public records Last synced Oct 30, 2026, 6:22 PM EDT

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Showing 1681–1704 of 2,538 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Parasomnia Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effect of Spinal Cord Stimulators on Restless Leg Syndrome

NCT07179406
View directory record Official record
Conditions
Restless Leg Syndrome (RLS), Spinal Cord Stimulation (SCS)
Interventions
H-Reflex, Somatosensory evoked potential (SSEP), Vibratory Electrophysiological Response Potential (ERP), Transcranial Magnetic Stimulation (TMS), Spinal Cord Stimulator (SCS) manipulation
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 30, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Improving Negative Stressful Perseverations in Insomnia to Revitalize Expecting Moms (INSPIRE)

NCT05356364
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Cognitive Behavioral Therapy for Insomnia (CBTI), Perinatal Understanding of Mindful Awareness for Sleep (PUMAS)
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 30, 2026, 6:22 PM EDT
Not yet recruiting Not applicable Interventional

Deaf CBT-TS to Reduce Suicide Risk

NCT07279363
View directory record Official record
Conditions
Depression - Major Depressive Disorder, Anxiety, PTSD - Post Traumatic Stress Disorder, Insomnia, Alcohol Use Disorder (AUD), Suicide Ideation
Interventions
Deaf CBT-TS
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 30, 2026, 6:22 PM EDT
Withdrawn Not applicable Interventional

Vasculaire Leg Compression Device for the Treatment of Restless Legs Syndrome - A Prospective Clinical Study

NCT01861652
View directory record Official record
Conditions
Restless Legs Syndrome,, Restless Legs,, Ekbom Syndrome
Interventions
Venous Health Systems Vasculaire Leg Compression Device
Device
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 16, 2015 · Synced Oct 30, 2026, 6:22 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effect of a Daily Magnesium and Melatonin Supplement on Sleep Quality in People With Nighttime Leg Cramps

NCT07651514
View directory record Official record
Conditions
Poor Sleep Quality, Leg Cramps, Nocturnal
Interventions
Magnesium and melatonin based multi-ingredient dietary supplementation, Placebo
Dietary Supplement · Other
Lead sponsor
StudySetGo
Network
Eligibility
40 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
7
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Palm Beach Gardens, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2026 · Synced Oct 30, 2026, 6:22 PM EDT
Completed Phase 3 Interventional Results available

A Study of Dexlansoprazole Modified Release Formulation to Treat Night Heartburn

NCT00627016
View directory record Official record
Conditions
Gastroesophageal Reflux
Interventions
Dexlansoprazole, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 65 Years
Enrollment
305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
43
States / cities
Tucson, Arizona • Anaheim, California • Garden Grove, California + 40 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2011 · Synced Oct 30, 2026, 6:22 PM EDT
Completed Phase 3 Interventional

Study of Melatonin: Sleep Problems in Alzheimer's Disease

NCT00000171
View directory record Official record
Conditions
Alzheimer Disease, Dyssomnias
Interventions
Melatonin
Drug
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
55 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
31
States / cities
Tucson, Arizona • Irvine, California • La Jolla, California + 26 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 30, 2026, 6:22 PM EDT
Completed Phase 3 Interventional Results available

"Twelve-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA"

NCT02348606
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
JZP-110, Placebo oral tablet
Drug
Lead sponsor
Jazz Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
476 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
45
States / cities
Glendale, Arizona • Scottsdale, Arizona • Little Rock, Arkansas + 38 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Oct 30, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Digital CBT-I for Insomnia Disorder

NCT05541055
View directory record Official record
Conditions
Insomnia Disorder
Interventions
digital CBT-I, Sleep hygiene education
Device · Other
Lead sponsor
Big Health Inc.
Industry
Eligibility
22 Years and older
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Oct 30, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Biomarkers in Obstructive Sleep Apnea Surgery

NCT00507078
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Surgical treatment for OSA
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 21, 2012 · Synced Oct 30, 2026, 6:22 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sleep More, Stress Less: 90-Day Trial of Neuralli Mood

NCT07717385
View directory record Official record
Conditions
Psychological Stress, Sleep Disturbance, Anxiety Symptoms, Depressive Symptoms, Occupational Burnout
Interventions
Neuralli Mood
Dietary Supplement
Lead sponsor
Efforia, Inc
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 30, 2026, 6:22 PM EDT
Recruiting Phase 4 Interventional

Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms

NCT07136415
View directory record Official record
Conditions
Menopausal Women, Insomnia
Interventions
Cognitive behavioral therapy for insomnia (CBT-i), Trazodone, Daridorexant
Behavioral · Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
40 Years to 62 Years · Female only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
5
States / cities
Boston, Massachusetts • Novi, Michigan • Winston-Salem, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 30, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Sleep Hygiene Education, ReadiWatchTM Actigraphy, and Telehealth Cognitive Behavioral Training for Insomnia Effect, on Symptom Relief for Men With Prostate Cancer Receiving Androgen Deprivation Therapy

NCT05582759
View directory record Official record
Conditions
Prostate Cancer, Sleep Disturbance, Fatigue, Cognitive Impairment
Interventions
teleCBT-I + SH/ReadiWatchTM, SH/ReadiWatchTM
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older · Male only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 17, 2024 · Synced Oct 30, 2026, 6:22 PM EDT
Completed No phase listed Observational

Stimulation Therapy for Apnea: Reporting Thoughts

NCT04768543
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Upper airway stimulation (Inspire Medical Systems, Inc.)
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 10, 2022 · Synced Oct 30, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Noninvasive Peripheral Nerve Stimulation for Medication-Naive and Medication-Refractory RLS

NCT05214963
View directory record Official record
Conditions
Restless Legs Syndrome
Interventions
NTX100 Neuromodulation System - Active, NTX100 Neuromodulation System - Sham
Device
Lead sponsor
Noctrix Health, Inc.
Industry
Eligibility
22 Years to 89 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Menlo Park, California • San Ramon, California • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 15, 2023 · Synced Oct 30, 2026, 6:22 PM EDT
Completed Not applicable Interventional Results available

A Development Study to Evaluate a Full-Face Mask for the Treatment of Obstructive Sleep Apnea

NCT03272763
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
F&P Toffee mask
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Roseville, California
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Oct 30, 2026, 6:22 PM EDT
Completed Phase 3 Interventional

A Clinical Research Study Testing Ropinirole Treatment for Restless Legs Syndrome

NCT00363857
View directory record Official record
Conditions
Restless Legs Syndrome (RLS), Restless Legs Syndrome
Interventions
Ropinirole
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 79 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
49
States / cities
Alabaster, Alabama • Birmingham, Alabama • Jasper, Alabama + 44 more
Source: ClinicalTrials.gov public record
Updated Oct 17, 2016 · Synced Oct 30, 2026, 6:22 PM EDT
Terminated Not applicable Interventional

Determination of Upper Airway Collapsibility During Routine CPAP Titration

NCT02566278
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Upper airway collapsibility (Pcrit)
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 79 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Oct 30, 2026, 6:22 PM EDT
Completed Phase 3 Interventional Results available

Montelukast and Inhaled Nasal Steroid Tx in Adult Obstructive Sleep Apnea (OSA)

NCT01089647
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
budesonide and montelukast, Placebo
Drug
Lead sponsor
Romaker & Associates
Other
Eligibility
18 Years to 100 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 3, 2018 · Synced Oct 30, 2026, 6:22 PM EDT
Terminated Not applicable Interventional Results available

Cardiovascular Improvements With MV ASV Therapy in Heart Failure

NCT01953874
View directory record Official record
Conditions
Acute Decompensated Heart Failure, Sleep Disordered Breathing
Interventions
MV ASV, Optimized Medical Treatment
Device · Drug
Lead sponsor
ResMed
Industry
Eligibility
21 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
14
States / cities
Huntsville, Alabama • Los Angeles, California • Denver, Colorado + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2018 · Synced Oct 30, 2026, 6:22 PM EDT
Completed Phase 3 Interventional

Efficacy and Safety of M100907 on Sleep Maintenance Insomnia With a Sub-study in Stable Type II Diabetes Mellitus

NCT00495885
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
volinanserin (M100907), Placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
848 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced Oct 30, 2026, 6:22 PM EDT
Completed No phase listed Observational

Extension Study of Original Protocol AERO C009 for Obstructive Sleep Apnea-hypopnea

NCT00849043
View directory record Official record
Conditions
Obstructive Sleep Apnea Hypopnea, Obstructive Sleep Apnea, OSAH
Interventions
Not listed
Lead sponsor
Ventus Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
13
States / cities
Wallingford, Connecticut • Gainesville, Florida • Atlanta, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2011 · Synced Oct 30, 2026, 6:22 PM EDT
Completed Not applicable Interventional

Behavioral Insomnia Therapy for Fibromyalgia

NCT00000397
View directory record Official record
Conditions
Fibromyalgia, Insomnia
Interventions
Behavioral insomnia therapy
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2004
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2014 · Synced Oct 30, 2026, 6:22 PM EDT
Recruiting No phase listed Observational

Digital and Plasma Biomarkers in Delirium

NCT07694206
View directory record Official record
Conditions
Critical Illness, Delirium in the Intensive Care Unit, Sleep Quality
Interventions
Not listed
Lead sponsor
Scripps Health
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
La Jolla, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 30, 2026, 6:22 PM EDT