Study of Melatonin: Sleep Problems in Alzheimer's Disease
Public ClinicalTrials.gov record NCT00000171. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This protocol is a multicenter clinical trial of melatonin for sleep disturbances associated with Alzheimer's disease (AD). Frequent nocturnal awakening is a common behavioral symptom of AD. Nighttime wandering and agitated behavior may result in injuries and sleep disruption for caregivers. Alternatives are sorely needed to the currently available sleep medications that have marginal efficacy and serious side effects. Melatonin is a naturally occurring hormone secreted by the pineal gland. It has soporific effects with oral administration and is well tolerated. It enhances sleep in normal older people. Melatonin also may help sleep disturbances associated with AD; however, this remains to be proven.
Study identification
- NCT ID
- NCT00000171
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- Not listed
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 55 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Not listed
- Primary completion
- Not listed
- Completion
- Not listed
- Last update posted
- Jun 24, 2005
United States locations
- U.S. sites
- 31
- U.S. states
- 20
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arizona | Tucson | Arizona | 85724-5023 | — |
| University of California Irvine Institute for Brain Aging and Dementia | Irvine | California | 92697-4285 | — |
| University of California, San Diego | La Jolla | California | 92037 | — |
| University of Southern California | Los Angeles | California | 90033-1039 | — |
| University of California, Los Angeles | Los Angeles | California | 90095-1769 | — |
| Yale University, Alzheimer's Disease ResearchUnit | New Haven | Connecticut | 06520-8037 | — |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32225 | — |
| Mount Sinai (Miami) | Miami | Florida | 33140 | — |
| University of South Florida | Tampa | Florida | — | — |
| Emory University | Atlanta | Georgia | 30329 | — |
| Augusta VA Medical Center | Augusta | Georgia | 30904 | — |
| Southern Illinois University | Springfield | Illinois | 62702 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Kentucky | Lexington | Kentucky | 40536-0230 | — |
| Johns Hopkins University | Baltimore | Maryland | 21224 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic at Rochester | Rochester | Minnesota | 14620 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| New York University Medical Center | New York | New York | 10016 | — |
| Columbia University | New York | New York | 11032 | — |
| University of Rochester Medical Center | Rochester | New York | 14620 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44120 | — |
| Oregon Health Sciences University | Portland | Oregon | 97201-3098 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104-4283 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| Brown University | Pawtucket | Rhode Island | 02860 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37212-8646 | — |
| University of Texas | Dallas | Texas | 75235 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Washington | Seattle | Washington | 98108 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT00000171, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 24, 2005 · Synced Oct 7, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT00000171 live on ClinicalTrials.gov.