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Showing 97–120 of 371 matching trials from the live ClinicalTrials.gov search.
Recruiting No phase listed Observational Accepts healthy volunteers

Natural History Study of Mitochondrial Myopathy

NCT05250375
Conditions
Primary Mitochondrial Disease
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
0 Years to 100 Years
Enrollment
1,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Muscle Weakness, ICU-acquired Weakness
Interventions
HMB protein supplement (3g), Nutritional Supplement
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Cerebrovascular Accident
Interventions
Transcranial magnetic stimulation (TMS)
Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Muscle Weakness
Interventions
High velocity low amplitude thoracic spine manipulation, Sham
Procedure
Lead sponsor
University of New England
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Portland, Maine
Conditions
Cerebrovascular Accident, Hemiparesis, Hemiplegia
Interventions
HAS Training, HAT training, Bimanual Training
Behavioral
Lead sponsor
New Jersey Institute of Technology
Other
Eligibility
18 Years to 80 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Newark, New Jersey
Conditions
Muscle Weakness | Patient, Pain
Interventions
Peripheral Nerve Block, Sham Block
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 99 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
San Francisco, California
Conditions
Spastic Cerebral Palsy
Interventions
Rolfing / Myofascial Structural Integration
Other
Lead sponsor
Stanford University
Other
Eligibility
1 Year to 3 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Stanford, California
Conditions
Stroke, Hemiparesis
Interventions
Cortical Stimulation and rehabilitation, Rehabilitation
Device · Other
Lead sponsor
Northstar Neuroscience
Industry
Eligibility
21 Years and older
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
21
States / cities
Tucson, Arizona • Los Angeles, California • San Francisco, California + 17 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Pupil-Indexed Noninvasive Neuromodulation

NCT06282406
Conditions
Paresis
Interventions
Transcutaneous Electrical Stimulation, Sham
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Stroke, Hemiparesis
Interventions
treadmill training
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Cerebrovascular Accident, Hemiparesis
Interventions
Ropinirole (+ physical therapy), (vs.) Placebo + physical therapy
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Orange, California
Conditions
Stroke, Chronic Stroke, Intracerebral Haemorrhage, Intracerebral Haemorrhage (ICH), Intracerebral Hemorrhage Basal Ganglia, Ischemic Stroke, Ischemic Stroke and Hemorrhagic Stroke, Hemiparesis After Stroke, Hemiplegia Following Ischemic Stroke, Hemiplegia and Hemiparesis, Hemiplegia and/or Hemiparesis Following Stroke, Middle Cerebral Artery Stroke
Interventions
Psilocybin (Usona Institute)
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vivo Prediabetes Study: Online, Live, and Interactive Strength Training for Older Adults With Prediabetes

NCT05497960
Conditions
PreDiabetes, Older Adults, Muscle Loss, Muscle Weakness
Interventions
Vivo workout
Behavioral
Lead sponsor
Eric Levian
Industry
Eligibility
60 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Closed Femur Fracture
Interventions
Blood Flow Restriction, Delfi PTSII Tourniquet System
Other · Device
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 55 Years
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
8
States / cities
Indianapolis, Indiana • Baltimore, Maryland • Bethesda, Maryland + 5 more
Conditions
Myasthenia Gravis
Interventions
eculizumab, Placebo
Drug
Lead sponsor
Alexion Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
21
States / cities
Birmingham, Alabama • Orange, California • Sacramento, California + 17 more
Conditions
Stroke, Hemiparesis, Upper Extremity Dysfunction
Interventions
Hemiparesis Therapy with VR
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Spinal Cord Injuries, Upper Extremity Paresis
Interventions
Active Vagus Nerve Stimulation, Placebo Vagus Nerve Stimulation
Device
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 64 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Results available

EMG Training for Altering Activation Patterns After Stroke

NCT03619772
Conditions
Stroke, Weakness, Muscle, Coordination Lack
Interventions
Bilateral, Unilateral
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Stroke, Upper Extremity Paresis
Interventions
Mental Practice
Behavioral
Lead sponsor
Adventist HealthCare
Other
Eligibility
18 Years to 90 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Rockville, Maryland
Conditions
Muscle Weakness, Renal Failure, Respiratory Comorbidities
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Stroke, Physical Disability
Interventions
real stimulation, No stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Muscle Weakness
Interventions
Neuromuscular electrical Stimulation (NMES), Sham Stimulation
Device
Lead sponsor
RML Specialty Hospital
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Hinsdale, Illinois
Completed Not applicable Interventional Results available

Power Training Combined With Interval Treadmill Training

NCT03625570
Conditions
Cerebral Palsy, Central Nervous System Diseases, Brain Damage, Chronic
Interventions
Power training combined with interval treadmill training, Strength training combined with traditional treadmill training
Behavioral
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
10 Years to 17 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
New Orleans, Louisiana • Seattle, Washington
Conditions
Stroke
Interventions
Magnesium Chloride, Placebo
Drug
Lead sponsor
Relox Medical, LLC
Industry
Eligibility
18 Years to 90 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
3
States / cities
Grand Rapids, Michigan • Suffern, New York • Toledo, Ohio