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Showing 1–24 of 832 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Parkinson's Disease and Parkinsonism Clear all
Completed No phase listed Observational

PA Behavior and HRQoL in Parkinson's Disease Patients Patients: Role of Social Cognitive Variables

NCT05575479
View directory record Official record
Conditions
Parkinson Disease, Idiopathic Parkinson Disease, Idiopathic Parkinson's Disease, Parkinson Disease, Idiopathic, Parkinson's Disease, Parkinson's Disease, Idiopathic
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 11, 2022 · Synced Jul 20, 2026, 6:43 PM EDT
Withdrawn Phase 2Phase 3 Interventional

Dexmedetomidine Effects on Microelectrode Recording in Deep Brain Stimulation

NCT00608231
View directory record Official record
Conditions
Parkinson's Disease, Essential Tremor, Dystonia
Interventions
Dexmedetomidine Hydrochloride Infusion, Normal Saline
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 30, 2014 · Synced Jul 20, 2026, 6:43 PM EDT
Completed Phase 1Phase 2 Interventional

Expiratory Muscle Training in Patients With Parkinson's Disease

NCT00843739
View directory record Official record
Conditions
Parkinson's Disease
Interventions
EMST - Active Treatment, sham EMST
Device
Lead sponsor
University of Florida
Other
Eligibility
35 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 19, 2011 · Synced Jul 20, 2026, 6:43 PM EDT
Completed Not applicable Interventional Results available

Light Therapy for PD - Dose Selection

NCT04291014
View directory record Official record
Conditions
Parkinson Disease, Sleep Disorder, Fatigue
Interventions
SunRay Light Boxes
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years and older
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
25
States / cities
Birmingham, Alabama • Phoenix, Arizona • Irvine, California + 20 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jul 20, 2026, 6:43 PM EDT
Recruiting No phase listed Observational

Physiological Brain Atlas Development

NCT00575081
View directory record Official record
Conditions
Parkinson's Disease, Obsessive Compulsive Disorder, Dystonia, Essential Tremor, Epilepsy
Interventions
Stereotactic brain procedures
Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
6 Years to 90 Years
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Jul 20, 2026, 6:43 PM EDT
Not listed Not applicable Interventional

Telehealth Allied Health Care With People Who Have Parkinson's Disease Living in Rural Nevada and Wyoming

NCT03381898
View directory record Official record
Conditions
Parkinson Disease
Interventions
Telehealth Exercise, speech therapy, medication management
Behavioral
Lead sponsor
University of Wyoming
Other
Eligibility
30 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
2
States / cities
Las Vegas, Nevada • Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated Dec 21, 2017 · Synced Jul 20, 2026, 6:43 PM EDT
Completed Not applicable Interventional

Automated Telehealth Diagnostics for Remote Parkinson Monitoring

NCT02152319
View directory record Official record
Conditions
Parkinson's Disease
Interventions
KHV reporting, Standard care
Device · Procedure
Lead sponsor
Great Lakes NeuroTechnologies Inc.
Industry
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2016 · Synced Jul 20, 2026, 6:43 PM EDT
Not listed Phase 1 Interventional

A Study of Weekly Subcutaneous Injections of SER-214 in Subjects With Parkinson's Disease (PD), to Determine the Safety, Tolerability and Pharmacokinetic (PK) Profile of SER-214

NCT02579473
View directory record Official record
Conditions
Parkinson's Disease
Interventions
SER-214
Drug
Lead sponsor
Serina Therapeutics
Industry
Eligibility
40 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
4
States / cities
Birmingham, Alabama • Hallandale, Florida • Augusta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Jul 20, 2026, 6:43 PM EDT
Recruiting Not applicable Interventional

Unlocking Movement Potential: Enhancing Parkinson's Disease Treatment With Robotic EksoSkeleton

NCT06225830
View directory record Official record
Conditions
Parkinson Disease
Interventions
Eksobionics Eksoskeleton NR
Device
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Jul 20, 2026, 6:43 PM EDT
Completed Not applicable Interventional

Non-contact Boxing Training and Traditional Therapeutic Exercise for Persons With Parkinson's Disease

NCT01014663
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Traditional Therapeutic Exercise, Non-Contact Boxing Training
Behavioral
Lead sponsor
University of Indianapolis
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 1, 2020 · Synced Jul 20, 2026, 6:43 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Imaging Biomarkers of Delayed Sequelae in Trauma Brain Injury

NCT01516281
View directory record Official record
Conditions
Traumatic Brain Injury, Parkinson's Disease
Interventions
Not listed
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 100 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Jul 20, 2026, 6:43 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Detecting Parkinson's Disease Through Speech Analysis

NCT03133611
View directory record Official record
Conditions
Parkinson Disease, REM Sleep Behavior Disorder
Interventions
Speech assessment, Routine clinical assessment
Other
Lead sponsor
Czech Technical University in Prague
Other
Eligibility
50 Years to 80 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 8, 2019 · Synced Jul 20, 2026, 6:43 PM EDT
Active, not recruiting No phase listed Observational

Early Longitudinal Imaging in Parkinson's Progression Markers Initiative Using [¹⁸F] AV-133 and DaTscan™

NCT04507139
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
Michael J. Fox Foundation for Parkinson's Research
Other
Eligibility
30 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
3
States / cities
New Haven, Connecticut • Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 30, 2024 · Synced Jul 20, 2026, 6:43 PM EDT
Recruiting Phase 4 Interventional

Comparing Antipsychotic Medications in LBD Over Time

NCT05590637
View directory record Official record
Conditions
Parkinson's Disease Psychosis, Dementia With Lewy Bodies
Interventions
Pimavanserin, Quetiapine
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
Not listed
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Jul 20, 2026, 6:43 PM EDT
Recruiting Not applicable Interventional

Simplified, Scalable, 24-hour Adaptive DBS in Parkinson's Disease

NCT07398157
View directory record Official record
Conditions
PD - Parkinson's Disease
Interventions
Medtronic Percept Deep Brain Stimulation (cDBS), Medtronic Percept Deep Brain Stimulation (daytime aDBS), Medtronic Percept Deep Brain Stimulation (nighttime aDBS)
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jul 20, 2026, 6:43 PM EDT
Completed Phase 2Phase 3 Interventional

Safety and Efficacy Study of SYN115 in Parkinson's Patients Using Levodopa to Treat End of Dose Wearing Off

NCT01283594
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Tozadenant (SYN115) 60 mg BID, Placebo, Levodopa (L-dopa), Tozadenant (SYN115) 120 mg BID, Tozadenant (SYN115) 180 mg BID, Tozadenant (SYN115) 240 mg BID
Drug
Lead sponsor
Biotie Therapies Inc.
Industry
Eligibility
30 Years to 80 Years
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
40
States / cities
Birmingham, Alabama • La Jolla, California • Loma Linda, California + 37 more
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Jul 20, 2026, 6:43 PM EDT
Completed Phase 3 Interventional Results available

Relapse Prevention Study of Pimavanserin in Dementia-related Psychosis

NCT03325556
View directory record Official record
Conditions
Dementia-related Psychosis
Interventions
Placebo, Pimavanserin 34 mg, Pimavanserin 20 mg
Drug
Lead sponsor
ACADIA Pharmaceuticals Inc.
Industry
Eligibility
50 Years to 90 Years
Enrollment
392 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
27
States / cities
Costa Mesa, California • Fullerton, California • Aventura, Florida + 22 more
Source: ClinicalTrials.gov public record
Updated Jun 20, 2021 · Synced Jul 20, 2026, 6:43 PM EDT
Completed Phase 1 Interventional

Improve Speech Using an In-the-ear Device in Parkinson's Disease

NCT00488657
View directory record Official record
Conditions
Parkinson's Disease, Dysarthria
Interventions
SpeechEasy Model ITC
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
25 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 17, 2013 · Synced Jul 20, 2026, 6:43 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Lu AF82422 in Healthy Non-Japanese and Japanese Subjects and in Patients With Parkinson's Disease

NCT03611569
View directory record Official record
Conditions
Healthy, Parkinson Disease
Interventions
Lu AF82422, Placebo
Drug
Lead sponsor
H. Lundbeck A/S
Industry
Eligibility
18 Years to 80 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
4
States / cities
Glendale, California • Hollywood, Florida • Orlando, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Jul 20, 2026, 6:43 PM EDT
Completed Phase 2 Interventional

A Study to Assess the PK and Pharmacodynamics of IPX203 in Patients With Advanced Parkinson's Disease

NCT02271503
View directory record Official record
Conditions
Parkinson's Disease
Interventions
CD-LD IR, IPX203 180 mg, IPX203 270 mg, Rytary 195 mg, Rytary 145 mg
Drug
Lead sponsor
Impax Laboratories, LLC
Industry
Eligibility
40 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
11
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Fountain Valley, California + 8 more
Source: ClinicalTrials.gov public record
Updated Nov 5, 2019 · Synced Jul 20, 2026, 6:43 PM EDT
Completed Not applicable Interventional Results available

Acupuncture for Fatigue in Parkinson's Disease

NCT01360229
View directory record Official record
Conditions
Parkinsons Disease
Interventions
Acupuncture, Acupuncture to treat fatigue in Parkinson disease
Procedure · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years to 99 Years
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 11, 2019 · Synced Jul 20, 2026, 6:43 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy Subjects

NCT02103894
View directory record Official record
Conditions
Alzheimer's Disease (AD), Parkinson's Disease (PD), Chronic Traumatic Encephalopathy (CTE), Progressive Supranuclear Palsy (PSP), Frontal Temporal Dementia (FTD), Pick's Disease, Tauopathies
Interventions
[18F]T807 ([18F]MNI-777)
Drug
Lead sponsor
Molecular NeuroImaging
Other
Eligibility
18 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 15, 2016 · Synced Jul 20, 2026, 6:43 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Test the Safety, Tolerability, and Pharmacokinetics of UCB0599 in Healthy Study Participants and Patients With Parkinson's Disease (PD)

NCT04875962
View directory record Official record
Conditions
Parkinson's Disease
Interventions
UCB0599, Placebo
Drug
Lead sponsor
UCB Biopharma S.P.R.L.
Industry
Eligibility
40 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
6
States / cities
Long Beach, California • Bay Harbor Islands, Florida • DeLand, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated May 5, 2021 · Synced Jul 20, 2026, 6:43 PM EDT
Completed Phase 2 Interventional

Development of Imaging, Clinical and Biochemical Bio-Markers for Parkinson's Disease

NCT00315250
View directory record Official record
Conditions
Parkinson's Disease, Parkinsonian Syndrome
Interventions
[123I]β-CIT
Drug
Lead sponsor
Institute for Neurodegenerative Disorders
Other
Eligibility
22 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 8, 2014 · Synced Jul 20, 2026, 6:43 PM EDT