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ClinicalTrials.gov public records Last synced Oct 11, 2026, 7:59 AM EDT

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Showing 217–240 of 1,864 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Parkinson Disease Clear all
Active, not recruiting Phase 3 Interventional

A Study of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022)

NCT05239728
View directory record Official record
Conditions
Carcinoma, Renal Cell
Interventions
Belzutifan, Pembrolizumab, Placebo
Drug · Biological
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years and older
Enrollment
1,800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
37
States / cities
Phoenix, Arizona • Duarte, California • La Jolla, California + 31 more
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 11, 2026, 7:59 AM EDT
Terminated Phase 2 Interventional Results available

Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's Disease

NCT01789047
View directory record Official record
Conditions
Idiopathic Parkinson's Disease, Drug Induced Dyskinesia
Interventions
Topiramate, Placebo, Amantadine
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
30 Years to 90 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
5
States / cities
Birmingham, Alabama • Tampa, Florida • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Oct 11, 2026, 7:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MBCT for People With Parkinson's Disease and Caregivers

NCT04469049
View directory record Official record
Conditions
Parkinson Disease, Anxiety, Depression
Interventions
Mindfulness-based cognitive therapy (MBCT)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced Oct 11, 2026, 7:59 AM EDT
Completed Phase 3 Interventional Results available

Phase II Subthalamic Nucleus (STN) vs. Globus Pallidus (GPi) Trial

NCT01076452
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Bilateral Deep Brain Stimulation
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
22 Years and older
Enrollment
299 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2009
U.S. locations
14
States / cities
Los Angeles, California • San Francisco, California • West Los Angeles, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2014 · Synced Oct 11, 2026, 7:59 AM EDT
Active, not recruiting Not applicable Interventional Results available

Parkinson's Disease: Enhancing Physical Therapy With Brain Stimulation for Treating Postural Instability.

NCT03981055
View directory record Official record
Conditions
Parkinson Disease
Interventions
Active Comparator: Active tDCS and Active TUS, Sham Comparator: Sham TDCS and Sham TUS, Physical Therapy
Device · Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
40 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 11, 2026, 7:59 AM EDT
Recruiting Not applicable Interventional

Neurologic Stem Cell Treatment Study

NCT02795052
View directory record Official record
Conditions
Neurologic Disorders, Nervous System Diseases, Neurodegenerative Diseases, Neurological Disorders, Stroke, Traumatic Brain Injury, Cadasil, Chronic Traumatic Encephalopathy, Cerebral Infarction, Cerebral Ischemia, Cerebral Stroke, Cerebral Hemorrhage, Parkinson, Multi-System Degeneration, MSA - Multiple System Atrophy, Progressive Supranuclear Palsy, ALS, Amyotrophic Lateral Sclerosis, Neuropathy, Diabetic Neuropathies, Alzheimer Disease, Dementia, Frontotemporal Dementia, Lewy Body Disease, Cognitive Impairment, Lewy Body Variant of Alzheimer Disease
Interventions
Intravenous and Intranasal BMSC
Procedure
Lead sponsor
MD Stem Cells
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
2
States / cities
Westport, Connecticut • Coral Springs, Florida
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 11, 2026, 7:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Cardiorespiratory Fitness Among Regular Exercisers With and Without Parkinson Disease and Across Different Modes of Group Exercise

NCT02547506
View directory record Official record
Conditions
Parkinson Disease
Interventions
Not listed
Lead sponsor
University of Indianapolis
Other
Eligibility
55 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 9, 2019 · Synced Oct 11, 2026, 7:59 AM EDT
Completed Not applicable Interventional

Exercise for Cognitive Excellence in Parkinson's Disease

NCT05720468
View directory record Official record
Conditions
Parkinson Disease
Interventions
Exercise, No Exercise
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
40 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 11, 2026, 7:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Parkinson's Diseases Susceptibility Genes and Pesticides

NCT00044590
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
18 Years and older
Enrollment
1,870 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 16, 2017 · Synced Oct 11, 2026, 7:59 AM EDT
Active, not recruiting Phase 3 Interventional

To Evaluate the Efficacy of CVN424 in Parkinson's Disease Participants With Motor Complications

NCT06553027
View directory record Official record
Conditions
Parkinson Disease
Interventions
CVN424 75 mg, CVN424 150 mg, Placebo
Drug
Lead sponsor
Cerevance
Industry
Eligibility
30 Years and older
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
53
States / cities
Birmingham, Alabama • Phoenix, Arizona • Aliso Viejo, California + 41 more
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 11, 2026, 7:59 AM EDT
Recruiting Phase 2 Interventional

18F-mFBG Cardiac Uptake With Lewy Body Dementia

NCT07176286
View directory record Official record
Conditions
Parkinson Disease (PD), Lewy Body Dementia (LBD)
Interventions
18F-MFBG
Drug
Lead sponsor
Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC)
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 11, 2026, 7:59 AM EDT
Completed Not applicable Interventional

Prospective Memory Training in Parkinson Disease

NCT03582670
View directory record Official record
Conditions
Parkinson Disease
Interventions
Strategy Training, Process Training, Control Group
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
50 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 6, 2021 · Synced Oct 11, 2026, 7:59 AM EDT
Completed Phase 2 Interventional

Comparison of IPX054, IR Carbidopa-Levodopa, and CR Carbidopa-Levodopa in Subjects With Parkinson's Disease

NCT00279825
View directory record Official record
Conditions
Idiopathic Parkinson's Disease
Interventions
IPX054 200 mg, IPX054 250 mg, CD-LD IR, CD-LD CR, IPX054 200 mg Placebo, IPX054 250 mg Placebo, CD-LD IR Placebo, CD-LD CR Placebo
Drug
Lead sponsor
Impax Laboratories, LLC
Industry
Eligibility
30 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
2
States / cities
Bingham Farms, Michigan • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 29, 2019 · Synced Oct 11, 2026, 7:59 AM EDT
Terminated No phase listed Observational

Neurogenic Dysphonia/Dysphagia Registry

NCT02493491
View directory record Official record
Conditions
Neurogenic Dysphonia, Neurogenic Dysphagia
Interventions
Not listed
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
18 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
12
States / cities
La Jolla, California • Sacramento, California • Augusta, Georgia + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2016 · Synced Oct 11, 2026, 7:59 AM EDT
Recruiting Not applicable Interventional

Treatment of Cognitive and Sensorimotor Deficits in Parkinson's Disease With High Definition Transcranial Direct Current Stimulation

NCT07534397
View directory record Official record
Conditions
PARKINSON DISEASE (Disorder)
Interventions
transcranial direct current stimulation, Sham transcranial direct current stimulation
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
50 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 11, 2026, 7:59 AM EDT
Not listed Not applicable Interventional

Cognitive-motor Training for PD

NCT01917903
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Gait-cognitive training, Identification of at risk variables
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
21 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Oct 11, 2026, 7:59 AM EDT
Not listed No phase listed Observational

Subthalamic Nucleus Deep Brain Stimulation in Speech Study

NCT05493670
View directory record Official record
Conditions
Parkinson Disease, Dysarthria
Interventions
Not listed
Lead sponsor
Jeremy Greenlee
Other
Eligibility
21 Years to 84 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 22, 2023 · Synced Oct 11, 2026, 7:59 AM EDT
Completed Not applicable Interventional Results available

Effects of Neuromodulation and Rehabilitation of the Locomotor Network in Freezing of Gait

NCT03273270
View directory record Official record
Conditions
Parkinson Disease With Freezing of Gait
Interventions
transcranial magnetic stimulation
Radiation
Lead sponsor
Medical University of South Carolina
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Oct 11, 2026, 7:59 AM EDT
Completed Phase 3 Interventional

Study Evaluating Sumanirole for the Treatment of the Signs and Symptoms of Early Parkinson's Disease.

NCT00036218
View directory record Official record
Conditions
Parkinson Disease
Interventions
sumanirole, ropinirole
Drug
Lead sponsor
Pfizer
Industry
Eligibility
30 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
93
States / cities
Hot Springs, Arkansas • Little Rock, Arkansas • Carmichael, California + 81 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2006 · Synced Oct 11, 2026, 7:59 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study

NCT06960096
View directory record Official record
Conditions
Deep Brain Stimulation, Parkinson Disease
Interventions
DBS combined with fMRI
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 11, 2026, 7:59 AM EDT
Terminated No phase listed Observational

The Long Term Impact of Initiating Pramipexole Versus Levodopa in Early Parkinson's Disease (CALM-PD Cohort Study)

NCT00804479
View directory record Official record
Conditions
Parkinson's Disease
Interventions
No intervention.
Other
Lead sponsor
University of Rochester
Other
Eligibility
Not listed
Enrollment
222 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 21, 2016 · Synced Oct 11, 2026, 7:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Autonomic Failure Patients for RNA Blood Sampling

NCT00742586
View directory record Official record
Conditions
Pure Autonomic Failure, Multiple System Atrophy, Parkinson's Plus Syndromes
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
50 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Oct 11, 2026, 7:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

GEnetic Counseling Through Virtual Visits in Parkinson's Disease

NCT04527146
View directory record Official record
Conditions
Parkinson Disease
Interventions
IMAGINE-PD, Virtual genetic counseling, Telephone genetic counseling
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years and older
Enrollment
370 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 11, 2026, 7:59 AM EDT
Active, not recruiting Not applicable Interventional

Transcranial Direct Current Stimulation for Cognitive Improvement in Parkinson's Patients

NCT03191916
View directory record Official record
Conditions
Parkinson Disease
Interventions
transcranial direct current stimulation, Sham (for transcranial direct current stimulation)
Device
Lead sponsor
Sanford Health
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Oct 11, 2026, 7:59 AM EDT