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Showing 1–24 of 537 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Partial Hearing Loss Clear all
Recruiting Not applicable Interventional

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

NCT06662058
View directory record Official record
Conditions
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Cutaneous Squamous Cell Carcinoma of the Head and Neck, Head and Neck Carcinoma of Unknown Primary, Head and Neck Squamous Cell Carcinoma, Hypopharyngeal Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma, Metastatic Cutaneous Squamous Cell Carcinoma of the Head and Neck, Metastatic Head and Neck Squamous Cell Carcinoma, Metastatic Hypopharyngeal Squamous Cell Carcinoma, Metastatic Laryngeal Squamous Cell Carcinoma, Metastatic Nasopharyngeal Squamous Cell Carcinoma, Metastatic Oral Cavity Squamous Cell Carcinoma, Metastatic Oropharyngeal Squamous Cell Carcinoma, Metastatic Paranasal Sinus Squamous Cell Carcinoma, Nasopharyngeal Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma, Paranasal Sinus Squamous Cell Carcinoma, Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck, Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma, Recurrent Laryngeal Squamous Cell Carcinoma, Recurrent Nasopharyngeal Squamous Cell Carcinoma, Recurrent Oral Cavity Squamous Cell Carcinoma, Recurrent Oropharyngeal Squamous Cell Carcinoma, Recurrent Paranasal Sinus Squamous Cell Carcinoma, Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8, Stage IV Hypopharyngeal Carcinoma AJCC v8, Stage IV Laryngeal Cancer AJCC v8, Stage IV Lip and Oral Cavity Cancer AJCC v8, Stage IV Nasopharyngeal Carcinoma AJCC v8, Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8, Stage IV Sinonasal Cancer AJCC v8
Interventions
Audiometric Test, Interview
Procedure · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Not applicable Interventional

Hearing Aid Education and Adaptation System

NCT02839759
View directory record Official record
Conditions
Hearing Loss
Interventions
TELLYHealth
Other
Lead sponsor
Healthcare Technologies and Methods, LLC
Industry
Eligibility
50 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Gainesville, Florida • Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated May 13, 2020 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Phase 1Phase 2 Interventional Results available

A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease

NCT01267994
View directory record Official record
Conditions
Sensorineural Hearing Loss, Autoimmune Inner Ear Disease
Interventions
Anakinra
Drug
Lead sponsor
Andrea Vambutas
Other
Eligibility
13 Years to 75 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Jan 9, 2018 · Synced Jul 24, 2026, 8:34 AM EDT
Recruiting Not applicable Interventional

Single-Sided Deafness and Asymmetric Hearing Loss

NCT04506853
View directory record Official record
Conditions
Hearing Loss, Unilateral, Hearing Loss, Sensorineural
Interventions
MED-EL Cochlear Implant System
Device
Lead sponsor
Med-El Corporation
Industry
Eligibility
5 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
5
States / cities
Chicago, Illinois • Iowa City, Iowa • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Not applicable Interventional Results available

Benefit of Assistive Listening Device for Lateralization

NCT05072457
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
Roger On microphone, Roger Select microphone
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 14, 2023 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study to Determine the Safety, Tolerability, and Pharmacokinetic Profile of HPN-07 and HPN-07 Plus NAC

NCT02259595
View directory record Official record
Conditions
Hearing Loss, Sensorineural Hearing Loss, Noise-Induced Hearing Loss
Interventions
HPN-07, NAC, Placebo
Drug
Lead sponsor
Otologic Pharmaceutics, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 30, 2015 · Synced Jul 24, 2026, 8:34 AM EDT
Active, not recruiting Phase 3 Interventional

SPI-1005 for the Treatment of Meniere's Disease (Open Label)

NCT06859788
View directory record Official record
Conditions
Meniere's Disease, Ménière's Disease
Interventions
Ebselen
Drug
Lead sponsor
Sound Pharmaceuticals, Incorporated
Industry
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
9
States / cities
Los Angeles, California • Boynton Beach, Florida • Delray Beach, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Evaluation of an Open-source Speech-processing Platform

NCT03686046
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
Exploratory use
Other
Lead sponsor
San Diego State University
Other
Eligibility
30 Years to 90 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Predicting Success With Hearing Aids

NCT00371449
View directory record Official record
Conditions
Hearing Loss, Presbycusis
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Mountain Home, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Jul 24, 2026, 8:34 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms

NCT06930560
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Hearing Loss, Cognitive Impairment
Interventions
HEARS-NPS device, HEARS-NPS program
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years to 100 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Jul 24, 2026, 8:34 AM EDT
Not listed Phase 4 Interventional

Evaluation of Benefit for Treatment of Single Sided Deafness (SSD) Between Two Bone Conduction Prosthetic Devices; Osseointegrated Implant Versus Maxilla Anchored Removable Oral Appliance ("SoundBite")

NCT01933386
View directory record Official record
Conditions
Single Sided Deafness
Interventions
SoundBite
Device
Lead sponsor
Sonitus Medical Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
Phoenix, Arizona • Novi, Michigan • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 28, 2013 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Not applicable Interventional Results available

The Performance-Perceptual Test as a Counseling Tool

NCT00126113
View directory record Official record
Conditions
Hearing Impairment
Interventions
PPT-based Counseling, Standard Educational Counseling
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
45 Years to 65 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 15, 2014 · Synced Jul 24, 2026, 8:34 AM EDT
Recruiting Not applicable Interventional

Effectiveness Comparison of 3D-Printed and Conventional Ear Tip Comfort in Individuals With Hearing Loss

NCT07228845
View directory record Official record
Conditions
Hearing Aids, Hearing Loss, Bilateral Sensorineural, 3D Printing
Interventions
BTE hearing aids with compatible ear tips (Third-party, FlexResin, Resin), BTE hearing aids with compatible ear tips (FlexResin, Resin, Third-party, FlexResin), BTE hearing aids with compatible ear tips (Resin, Third-party, FlexRes)
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 89 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain and Cognitive Changes After Reasoning or Physical Training in Cognitively Normal Seniors

NCT00977418
View directory record Official record
Conditions
Hearing Impaired
Interventions
SMART- Strategic Memory and Reasoning Training, Physical Exercise
Behavioral · Other
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
60 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2016 · Synced Jul 24, 2026, 8:34 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Contributions of Age Related Changes in the Sound Localization Pathway to Central Hearing Loss

NCT04513782
View directory record Official record
Conditions
Healthy Individuals, Hearing Loss, Central
Interventions
Audiological Assessments
Diagnostic Test
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years to 89 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Not applicable Interventional Results available

Cochlear Implantation in Adults With Asymmetric Hearing Loss Clinical Trial

NCT03052920
View directory record Official record
Conditions
Hearing Loss
Interventions
Cochlear implant
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
4
States / cities
Los Angeles, California • Kansas City, Missouri • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Tracking Neurodegeneration in Early Wolfram Syndrome

NCT02455414
View directory record Official record
Conditions
Type 1 Diabetes, Diabetes Insipidus, Diabetes Mellitus, Wolfram Syndrome
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
1 Day and older
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 10, 2018 · Synced Jul 24, 2026, 8:34 AM EDT
Recruiting Not applicable Interventional

Preschool Hearing Screening

NCT06058767
View directory record Official record
Conditions
Hearing Loss, Hearing Disorders in Children, Hearing Loss, Sensorineural, Hearing Loss, Conductive, Hearing Loss, Unilateral, Hearing Loss, Noise-Induced, Hearing Loss, Mixed, Hearing Loss, Bilateral
Interventions
Otoacoustic Emissions Testing, Pure Tone Audiometry
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
2 Years to 6 Years
Enrollment
13,764 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Safety, Tolerability and Efficacy for CGF166 in Patients With Unilateral or Bilateral Severe-to-profound Hearing Loss

NCT02132130
View directory record Official record
Conditions
Unilateral Severe to Profound Hearing Loss OR Bilateral Severe to Profound Hearing Loss
Interventions
CGF166
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
4
States / cities
Kansas City, Kansas • Baltimore, Maryland • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hearing Aid Noise Reduction in Pediatric Users (Oticon Study)

NCT03771287
View directory record Official record
Conditions
Hearing Impairment, Hearing Loss, Sensorineural
Interventions
Oticon OpenSound Navigator speech enhancement algorithm, Oticon omni-directional microphone algorithm
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Years to 13 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced Jul 24, 2026, 8:34 AM EDT
Completed No phase listed Observational

Hearing Loss and Dizziness in Patients Receiving Oxaliplatin for Solid Tumors

NCT00305799
View directory record Official record
Conditions
Neurotoxicity, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
management of therapy complications
Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2014
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 23, 2014 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hearing Aid Signal Processing Comparative Study

NCT04839289
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
Receiver-in-canal hearing instrument; Manufacturer A, Receiver-in-canal hearing instrument; Manufacturer B
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years to 100 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Aurora, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Jul 24, 2026, 8:34 AM EDT
Completed Phase 3 Interventional Results available

Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

NCT00716976
View directory record Official record
Conditions
Brain Tumor, Central Nervous System Tumor, Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor, Liver Cancer, Neuroblastoma, Ototoxicity, Ovarian Cancer, Sarcoma
Interventions
sodium thiosulfate, examination
Drug · Procedure
Lead sponsor
Children's Oncology Group
Network
Eligibility
1 Year to 18 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2021
U.S. locations
68
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 61 more
Source: ClinicalTrials.gov public record
Updated Nov 8, 2023 · Synced Jul 24, 2026, 8:34 AM EDT
Recruiting Not applicable Interventional

Stem Cell Ophthalmology Treatment Study II

NCT03011541
View directory record Official record
Conditions
Retinal Disease, Age-Related Macular Degeneration, Retinitis Pigmentosa, Stargardt Disease, Optic Neuropathy, Nonarteritic Ischemic Optic Neuropathy, Optic Atrophy, Optic Nerve Disease, Glaucoma, Leber Hereditary Optic Neuropathy, Blindness, Vision Loss Night, Vision Loss Partial, Vision, Low, Retinopathy, Maculopathy, Macular Degeneration, Retina Atrophy
Interventions
Arm 1
Procedure
Lead sponsor
MD Stem Cells
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
2
States / cities
Westport, Connecticut • Coral Springs, Florida
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Jul 24, 2026, 8:34 AM EDT