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ClinicalTrials.gov public records Last synced Nov 11, 2026, 3:21 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 2809–2832 of 3,983 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Pathophysiology Clear all

Conditions: High Tone Pelvic Floor Dysfunction
Interventions: Cyclobenzaprine, Pelvic floor massage wand, Pelvic floor physical therapy; Drug · Device · Procedure
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 65 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: ME/CFS, ME/CFS Following EBV-associated Infectious Mononucleosis, ME/CFS Following COVID-19, Chronic Fatigue, Chronic Fatigue Syndrome (CFS), Brain Fog, Cognitive Impairment, Cognitive Dysfunction
Interventions: Processing Speed Training, In-session Instrumental Activities of Daily Living Training, Transfer Package, Follow Up Phone Calls, Trans-auricular Vagus Nerve Stimulation: High Intensity, In-session Brain Health Training, Reaction Time Training, Trans-auricular Vagus Nerve Stimulation: Low Intensity; Behavioral · Procedure
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Pain, Function, Anxiety, Depression, Arthroplasty, Replacement, Knee, Veterans
Interventions: Acceptance and Commitment Therapy (ACT), Attention Control (AC); Behavioral · Other
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years and older
Enrollment: 402 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Breastfeeding, Postpartum Sexual Dysfunction, Vaginal Atrophy
Interventions: Estradiol, Vaginal Moisturizer; Drug · Device
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Cognitive Decline
Interventions: Behavioral Treatment; Behavioral
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 60 Years and older
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Depression, Anxious Depression, Major Depressive Disorder
Interventions: Ketamine, Magnetic Resonance Imaging (MRI); Drug · Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 64 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Prediabetes, Healthy (Controls)
Interventions: Ketone Monoester (KE), Placebo; Dietary Supplement
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 60 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Birmingham, Alabama

Conditions: Effects of Chemotherapy
Interventions: Not listed
Lead sponsor: University of Pennsylvania; Other
Eligibility: 20 Years to 50 Years · Female only
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Insulin Resistance, Obesity, Obesity, Abdominal
Interventions: Metformin Hydrochloride, Placebo Oral Tablet; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 65 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Prehypertension, Hypertension, Overweight and Obesity, Elevated Blood Pressure, Endothelial Dysfunction, Vascular Stiffness, Sleep
Interventions: Cardiovascular Assessments, Actigraphy, Laboratory assessments, Emotional/Behavioral Assessments; Diagnostic Test
Lead sponsor: Johns Hopkins University; Other
Eligibility: Up to 22 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Melanoma, NSCLC, Hepatocellular Carcinoma, Urothelial Cancer, Gastric Adenocarcinoma, HNSCC, Esophageal Adenocarcinoma, Microsatellite Instability-High Solid Malignant Tumor
Interventions: Nivolumab or Pembrolizumab (dependent upon approved indication), Metformin, Rosiglitazone; Drug
Lead sponsor: Dan Zandberg; Other
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2032
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Erectile Dysfunction
Interventions: Placebo, Avanafil; Drug
Lead sponsor: VIVUS LLC; Industry
Eligibility: 18 Years to 70 Years · Male only
Enrollment: 298 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 51
States / cities: Phoenix, Arizona • Laguna Hills, California • Los Angeles, California + 42 more

Conditions: Anesthesia, General, Recovery Period, Anesthesia
Interventions: BIS monitoring; Procedure
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Male Erectile Disorder, Prostate Adenocarcinoma, Erectile Dysfunction, CTCAE, Impotence
Interventions: Atorvastatin, Pentoxifylline, Vitamin E Compound; Drug · Dietary Supplement
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older · Male only
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Healthy, Gastrointestinal Dysfunction, Cold Symptom, Flu Symptom
Interventions: Whole Cell Algae Fermentate, Placebo; Dietary Supplement
Lead sponsor: Kemin Foods LC; Industry
Eligibility: 21 Years to 60 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Addison, Illinois

Conditions: Left Ventricular Dysfunction
Interventions: Adult stem cells, Placebo; Biological
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 21 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 5
States / cities: Gainesville, Florida • Minneapolis, Minnesota • Cleveland, Ohio + 2 more

Conditions: Hypertension, Mild Cognitive Impairment
Interventions: Candesartan, Lisinopril; Drug
Lead sponsor: Emory University; Other
Eligibility: 55 Years and older
Enrollment: 176 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Mild Cognitive Impairment, Memory Impairment
Interventions: IHT Treatment, Sham-IHT Control; Device · Other
Lead sponsor: University of North Texas Health Science Center; Other
Eligibility: 55 Years to 79 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Endothelial Dysfunction, Vascular Stiffness, Left Ventricular Hypertrophy, Left Ventricular Dysfunction
Interventions: Sodium Reduction Intervention; Behavioral
Lead sponsor: Tulane University; Other
Eligibility: 40 Years and older
Enrollment: 256 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Cognitive Dysfunction, Alzheimer's Disease
Interventions: Aducanumab, Placebo; Drug
Lead sponsor: Biogen; Industry
Eligibility: 50 Years to 85 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 22
States / cities: Phoenix, Arizona • Tucson, Arizona • Fullerton, California + 18 more

Conditions: Hemodialysis-Induced Symptom, Mitochondrial Diseases
Interventions: Icatibant, Placebo; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 78 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Panic Disorder
Interventions: Not listed
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 18 Years to 60 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Ischemia-Reperfusion Injury, Lung Transplantation
Interventions: Repertaxin, Placebo; Drug · Other
Lead sponsor: Dompé Farmaceutici S.p.A; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 5
States / cities: Los Angeles, California • Denver, Colorado • St Louis, Missouri + 2 more

Conditions: Congestive Heart Failure
Interventions: Nesiritide, Placebo, Saline; Drug
Lead sponsor: Horng Chen; Other
Eligibility: 18 Years and older
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Rochester, Minnesota

Search by objective public record fields.

Comparing Adjuvant Treatments for High Tone Pelvic Floor Dysfunction

ME/CFS Brain Fog: Cognitive Rehabilitation Trial

Preventing Persistent Post-Surgical Pain and Dysfunction

Postpartum Vaginal Estrogen for Breastfeeding Patients

Multicomponent Program for Addressing Cognition in Rural Communities

Ketamine for Depression: An MRI Study

Effects of Exogenous Ketones on Cognitive Function in Older Adults With Prediabetes?

Assessing Urinary Hormones in Female Cancer Survivors

Metformin Effect on Brain Function in Insulin Resistant Elderly People

Be-HealthY: Behavioral Risk Factors for Poor Vascular Health in Youth

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

Research Evaluating an Investigational Medication for Erectile Dysfunction - Post-Prostatectomy

Recovery From General Anesthesia

Pentoxifylline, Atorvastatin, and Vitamin E in Treating Patients With Erectile Dysfunction After Radiation Therapy for Prostate Cancer

Efficacy of a Whole Cell Algae Fermentate on Gut Health and Overall Immune Function in Healthy Adults With Mild Gastrointestinal Issues

Use of Adult Autologous Stem Cells in Treating People Who Have Had a Heart Attack (The TIME Study)

CAndesartan vs LIsinopril Effects on the BRain

IHT for Mild Cognitive Impairment

Sodium Lowering Vascular Effects Trial

A Study of Aducanumab in Participants With Mild Cognitive Impairment Due to Alzheimer's Disease or With Mild Alzheimer's Disease Dementia to Evaluate the Safety of Continued Dosing in Participants With Asymptomatic Amyloid-Related Imaging Abnormalities

Mitochondria and Chronic Kidney Disease

Neurobiological Mechanisms in Panic Disorder

Repertaxin in Prevention of Primary Graft Dysfunction After Lung Transplantation

Natriuretic Peptide System as Therapy in Human Preclinical Left Ventricle Dysfunction