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ClinicalTrials.gov public records Last synced Nov 13, 2026, 6:15 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 3025–3048 of 3,984 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Pathophysiology Clear all

Conditions: Supra-sacral Spinal Cord Injury, Spinal Cord Injury, Urinary Incontinence
Interventions: CBD; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Migraine Disorders, Migraine, Classic, Migraine Without Aura
Interventions: Nitroglycerin; Other
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2025
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Cystic Fibrosis
Interventions: Acute Antioxidant, Chronic Antioxidant, Placebo; Dietary Supplement · Other
Lead sponsor: Augusta University; Other
Eligibility: 7 Years and older
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2027
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Pelvic Pain, Healthy
Interventions: Transcranial Direct Current Stimulation; Device
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 64 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Aging, Endothelial Dysfunction, Arterial Stiffness
Interventions: Fisetin, Placebo; Dietary Supplement · Other
Lead sponsor: University of Colorado, Boulder; Other
Eligibility: 65 Years and older
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Boulder, Colorado

Conditions: Opioid Induced Constipation (OIC)
Interventions: placebo, NKTR-118; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years and older
Enrollment: 207 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 33
States / cities: Huntsville, Alabama • Pinson, Alabama • Tucson, Arizona + 30 more

Conditions: Endothelial Dysfunction
Interventions: Sapropterin Dihydrochloride, Sapropterin Dihydrochloride and Vitamin C; Drug
Lead sponsor: BioMarin Pharmaceutical; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Hackensack, New Jersey

Conditions: Mild Cognitive Impairment
Interventions: Not listed
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 20 Years to 100 Years
Enrollment: 116 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Alzheimers Disease, Postoperative Delirium, Post Operative Cognitive Dysfunction
Interventions: Total intravenous anesthesia with propofol, General anesthesia with isoflurane; Drug
Lead sponsor: Duke University; Other
Eligibility: 60 Years and older
Enrollment: 191 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2019
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: NASH/MASH, NAFLD/MASLD
Interventions: Efruxifermin, Placebo; Drug
Lead sponsor: Akero Therapeutics, Inc; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 139
States / cities: Birmingham, Alabama • Chandler, Arizona • Flagstaff, Arizona + 117 more

Conditions: Hematopoietic Stem Cell Transplantation, Cognitive Impairments, Sleep, Depression, Fatigue, Quality of Life
Interventions: Intervention systematic light exposure, Comparison systematic light exposure; Device
Lead sponsor: Northwestern University; Other
Eligibility: 21 Years and older
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: SCHIZOPHRENIA 1 (Disorder), Schizo Affective Disorder
Interventions: transcranial direct current stimulation, Sham stimulation; Device
Lead sponsor: Nathan Kline Institute for Psychiatric Research; Other
Eligibility: 18 Years to 55 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Orangeburg, New York

Conditions: Congestive Heart Failure
Interventions: Avandia (Rosiglitazone), Avanclia (Rosiqlitazone); Drug
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 22 Years and older
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2007
U.S. locations: 2
States / cities: Bethesda, Maryland

Conditions: Alzheimer Disease, Mild Cognitive Impairment
Interventions: Multidomain precision medicine intervention; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 452 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Patent Foramen Ovale, Cardiac Implantable Electronic Device
Interventions: Apixaban, Placebo; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Painful Bladder Syndrome, Interstitial Cystitis, Pelvic Floor; Insufficiency, Bowel Dysfunction, Sexual Dysfunction, Pelvic Floor; Incompetency
Interventions: Changing the Interstim parameter of '' Frequency" in patients with Interstitial Cystitis; Other
Lead sponsor: Pelvic and Sexual Health Institute; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Mild Cognitive Impairment
Interventions: Lithium Carbonate, Placebo oral capsule; Drug
Lead sponsor: Ariel Gildengers, MD; Other
Eligibility: 60 Years and older
Enrollment: 83 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Stroke Volume Variation, Diastolic Dysfunction
Interventions: Trans thoracic Ultrasound Examination, Intravenous fluid administration; Procedure · Other
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Multiple System Atrophy
Interventions: ATH434 dose level 1, ATH434 dose level 2, Placebo; Drug
Lead sponsor: Alterity Therapeutics; Industry
Eligibility: 30 Years to 75 Years
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 6
States / cities: La Jolla, California • Chicago, Illinois • Baltimore, Maryland + 3 more

Conditions: Myocardial Dysfunction, Heart Failure, Inflammation
Interventions: Dapagliflozin, MRI scan, CMR imaging; Drug · Device
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years to 90 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Type 2 Diabetes Mellitus, Impaired Glucose Tolerance, Non-Alcoholic Fatty Liver Disease, Obesity, Childhood
Interventions: Semaglutide Pen Injector, Placebo; Drug
Lead sponsor: Yale University; Other
Eligibility: 10 Years to 21 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Neuropsychiatric Post-Acute Sequelae of SARS-CoV-2 Infection
Interventions: PET Tracer, MRI Tracer, 3T PET/MRI; Drug · Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 50 Years
Enrollment: 30 participants
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Mild Cognitive Impairment
Interventions: Auditory stimulation during sleep, Sham Intervention; Other
Lead sponsor: Northwestern University; Other
Eligibility: 60 Years and older
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Parkinson Disease, Huntington Disease, Autistic Spectrum Disorders, Fragile X Syndrome, Alzheimer Disease, Mild Cognitive Impairment
Interventions: [18F]FPEB; Drug
Lead sponsor: Institute for Neurodegenerative Disorders; Other
Eligibility: 18 Years to 85 Years
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2016
U.S. locations: 1
States / cities: New Haven, Connecticut

Search by objective public record fields.

CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury

Understanding the Pathophysiology of Migraine Pain

Mechanisms for Vascular Dysfunction and Exercise Tolerance in CF

Transcranial Direct Stimulation in Chronic Pelvic Pain

Fisetin to Improve Vascular Function in Older Adults

A Phase 2, Double-Blind, Multiple-Dose Escalation Study to Evaluate NKTR-118 (Oral PEG-Naloxol) in Patients With Opioid-Induced Constipation (OIC)

A Phase 2, Pharmacokinetic (PK) Study of 6R-BH4 Alone or 6R-BH4 With Vitamin C in Subjects With Endothelial Dysfunction

PET Measures of CSF Clearance in Preclinical Alzheimer's Disease

Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care

A Study Evaluating Efruxifermin in Subjects With Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disease (NAFLD)/Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

The "Light for the Brain" Study

Non-invasive Brain Stimulation Using Tdcs of the Third (of Many) Visual Pathways

Rosiglitazone to Treat Patients With Heart Failure and Glucose Intolerance or Type II Diabetes

The Comparative Effectiveness Dementia & Alzheimer's Registry

Patients With Patent Foramen Ovale and Endocardial Device Leads on Apixaban for Prevention of Paradoxical Emboli

Clinical Efficacy of Changing the InterStim® Parameters in Patients With Interstitial Cystitis/Painful Bladder Syndrome

Lithium As a Treatment to Prevent Impairment of Cognition in Elders

Effect of Diastolic Dysfunction on Dynamic Cardiac Monitors

Study of ATH434 in Participants with Multiple System Atrophy

The Effect of Inflammation in Heart Failure

Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease

Neuropsychiatric Post-Acute Sequelae of SARS-CoV-2 (PASC) Using TSPO Positron Emission Tomography (PET) and MRI

Auditory Stimulation of Slow Wave Sleep and Memory in Mild Cognitive Impairment and Older Adults

A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions