Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Nov 8, 2026, 1:36 AM EST

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Showing 337–360 of 3,978 matching trials from the live ClinicalTrials.gov search.
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Behavioral and Physiological Effects of Visual Training

NCT00526942
Conditions
Healthy
Interventions
SAAGE-designed, visual memory-based cognitive training
Behavioral
Lead sponsor
Posit Science Corporation
Industry
Eligibility
60 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
San Francisco Bay Area, California
Conditions
Metabolic-dysfunction Associated Liver Disease (MASLD)
Interventions
Healthy Liver/Hígado Sano program, Usual Care
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Conditions
Cognitive Dysfunction
Interventions
standard Community-Friendly Health Recovery Program- Biobehavioral (CHRP-BB), enhanced Community-Friendly Health Recovery Program- Biobehavioral (CHRP-BB)
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Alzheimer Disease, Cognitive Dysfunction, Dementia
Interventions
JNJ-63733657, Placebo
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
55 Years to 80 Years
Enrollment
523 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
55
States / cities
Birmingham, Alabama • Phoenix, Arizona • Irvine, California + 47 more
Not listed Not applicable Interventional Accepts healthy volunteers

Elucidating the Necessary Active Components of Training

NCT05366023
Conditions
Alzheimer Disease, Cognitive Change, Cognitive Impairment
Interventions
BUD1, BUD2, TDD1, TDD2, CSA10, CSA20, CSA30, CSA40
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
55 Years to 85 Years
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Seneca, South Carolina
Conditions
Post-acute Sequelae of COVID-19, Depressive Symptoms, Cognitive Dysfunction
Interventions
CI-581a, CI-581b
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Conditions
Mild Cognitive Impairment
Interventions
No intervention is part of this study but patients use an EEG device during observational data collection.
Device
Lead sponsor
VA Boston Healthcare System
Federal
Eligibility
50 Years to 100 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Jamaica Plain, Massachusetts
Conditions
Mild Cognitive Impairment
Interventions
Daily Enhancement Meaningful Activity (DEMA), Information Support (IS)
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
21 Years to 95 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Results available

Technology and Family Thriving Study

NCT05150990
Conditions
Alzheimer Disease, Dementia, Caregiver Burnout, Quality of Life, Mental Health Wellness 1, Loneliness, Family Relationship
Interventions
Virtual Reality, Video Chat
Behavioral
Lead sponsor
University of California, Santa Barbara
Other
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
27
States / cities
Calabasas, California • Camarillo, California • Goleta, California + 16 more
Conditions
Endothelial Dysfunction, Hemolysis Intravascular, Cardiovascular Diseases, Cardiovascular Risk Factor
Interventions
Nitric Oxide, Reactive Hyperemia Index, Endothelial Cells Collection
Drug · Diagnostic Test · Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Boston, Massachusetts
Conditions
Alzheimer's Disease, Mild Cognitive Impairment
Interventions
Insulin LISPRO
Drug
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
50 Years to 95 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Shreveport, Louisiana
Active, not recruiting Not applicable Interventional

A Study of Healthy Microbiome, Healthy Mind

NCT06020703
Conditions
Critical Illness, COVID-19, PICS, Cognitive Impairment, Mental Health Impairment, Weakness, Muscle, Dysbiosis
Interventions
Fermented Food Diet
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Phase 4 Interventional Results available

Intraductal Meibomian Gland Probing Trial

NCT02256969
Conditions
Meibomian Gland Dysfunction
Interventions
Blephamide, GenTeal PM Night-Time, Meibomian Gland Probing, Sham Meibomian Gland Probing
Drug · Procedure
Lead sponsor
Joseph B. Ciolino, MD
Other
Eligibility
18 Years to 89 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Depression, Dementia, Mild Cognitive Impairment, Treatment Resistant Depression, Major Depressive Disorder, Treatment-Refractory Depression, Late Life Depression, Geriatric Depression
Interventions
Aripiprazole Augmentation, Bupropion Augmentation, Switch to bupropion, Lithium Augmentation, Switch to nortriptyline
Drug
Lead sponsor
Centre for Addiction and Mental Health
Other
Eligibility
60 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
3
States / cities
Los Angeles, California • St Louis, Missouri • New York, New York
Conditions
Pelvic Organ Prolapse
Interventions
Restorelle Direct Fix A, Restorelle Direct Fix P, Native Tissue Repair Anterior, Native Tissue Repair Posterior
Device · Procedure
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
810 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
33
States / cities
Agoura Hills, California • Stanford, California • Denver, Colorado + 30 more
Conditions
Atrial Fibrillation, Mild Cognitive Impairment, Dementia
Interventions
Not listed
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
50 Years to 75 Years
Enrollment
888 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Austin, Texas
Terminated Not applicable Interventional Results available

Dual Site Left Ventricular (LV) Pacing

NCT00944125
Conditions
Congestive Heart Failure, LV Dysfunction
Interventions
Dual Site LV Pacing, BiV Pacing
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Lake Geneva, Wisconsin • Milwaukee, Wisconsin
Terminated No phase listed Observational

Surviving Daily Life

NCT07054723
Conditions
Stress, Cognitive Change, Breast Cancer, Breast Carcinoma, Breast Neoplasm, Cognitive Dysfunction
Interventions
Mobile Daily Diary
Behavioral
Lead sponsor
Thomas Jefferson University
Other
Eligibility
40 Years and older · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Chronic Heart Failure, Cognitive Impairment
Interventions
Angiotensin-(1-7), Memory Training
Drug · Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
55 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Tucson, Arizona
Completed Phase 2 Interventional Accepts healthy volunteers

Thinking, Walking Outcomes by Type of Exercise

NCT01635348
Conditions
Gait Disorder, Sensorimotor, Cognitive Disorder
Interventions
motor skill gait exercise, aerobic gait intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Alzheimer Disease
Interventions
Self-Guided Lifestyle Intervention, Structured Lifestyle Intervention
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years to 79 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
6
States / cities
Sacramento, California • Chicago, Illinois • Downers Grove, Illinois + 3 more
Conditions
Graft vs Host Disease, Sjogren's Syndrome
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Erectile Dysfunction, Sexual Dysfunction, Physiological
Interventions
ARIES (Extracorporal Shock Wave Application)
Device
Lead sponsor
Dornier MedTech Systems
Industry
Eligibility
21 Years to 75 Years · Male only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Diego, California
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
Sleep study-guided adjustment of NIV, Standard initiation of NIV
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
New York, New York