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ClinicalTrials.gov public records Last synced Nov 8, 2026, 4:43 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 481–504 of 3,978 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Pathophysiology Clear all

Conditions: Dementia, Cognitive Decline, Cognitive Impairment, Developmental Delay
Interventions: Not listed
Lead sponsor: Duke University; Other
Eligibility: Not listed
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2014
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Heart Diseases, Coronary Disease, Coronary Artery Disease, Cardiovascular Diseases, Myocardial Ischemia, Artery Occlusion, Aspirin Sensitivity, Clopidogrel, Poor Metabolism of, Platelet Dysfunction, Platelet Thrombus
Interventions: Clopidogrel, Aspirin; Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 20 Years and older
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Lancaster, Pennsylvania

Conditions: Gastrointestinal Dysfunction, Metabolic Disturbance
Interventions: High Dose Hemp Fiber Bar, Low Dose Hemp Fiber Bar, Placebo; Dietary Supplement
Lead sponsor: Appalachian State University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Kannapolis, North Carolina

Conditions: Alzheimer Disease
Interventions: sabirnetug, Placebo; Drug
Lead sponsor: Acumen Pharmaceuticals; Industry
Eligibility: 50 Years to 90 Years
Enrollment: 542 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 44
States / cities: Carlsbad, California • Fullerton, California • Irvine, California + 40 more

Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Cancer-related Cognitive Dysfunction
Interventions: Accelerometry, Aerobic Exercise, Electronic Health Record Review, Functional Magnetic Resonance Imaging, Gait Assessment Test, Health Education, Interview, Neurocognitive Assessment, Physical Performance Testing, Questionnaire Administration; Procedure · Other · Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 50 Years and older · Female only
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: Aging, Cognitive Impairment, Sleep
Interventions: Sleep health and mindfulness intervention; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 55 Years and older
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Interstitial Cystitis, Sexual Dysfunction, Pelvic Pain, Incontinence
Interventions: Not listed
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years and older · Female only
Enrollment: 2,923 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2015
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Cognitive Impairment, Hypertension, Aging
Interventions: candesartan, lisinopril, hydrochlorothiazide, nifedipine, long acting, metoprolol, long-acting; Drug
Lead sponsor: University of Southern California; Other
Eligibility: 60 Years and older
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 2
States / cities: Los Angeles, California • Boston, Massachusetts

Conditions: Diastolic Dysfunction, Coronary Artery Disease, General Anesthesia
Interventions: Not listed
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia, Erectile Dysfunction
Interventions: ProstaThrive™ Supplement, Placebo; Dietary Supplement
Lead sponsor: Optimale; Industry
Eligibility: 40 Years and older · Male only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Internet-based Intervention, Web-based Intervention, Online Intervention, Erectile Dysfunction, Telemedicine
Interventions: An automated patient-reported outcome data collection and adverse event surveillance tool; Other
Lead sponsor: Ro; Industry
Eligibility: 18 Years and older · Male only
Enrollment: 2,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Meibomian Gland Dysfunction (MGD)
Interventions: Vevye(Cyclosporine 0.1% Ophthalmic Solution); Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Spinal Cord Injuries, Cardiovascular Diseases, Endothelial Dysfunction
Interventions: Brachial intra-arterial infusion of vasoactive and antioxidant drugs (acetylcholine, nitroprusside, ascorbic acid), venous occlusion plethysmography, Acetylcholine, Sodium Nitroprusside, Ascorbic acid, venous phlebotomy; Procedure · Drug
Lead sponsor: Craig Hospital; Other
Eligibility: 18 Years to 89 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Englewood, Colorado

Conditions: Preeclampsia, Preeclampsia Postpartum
Interventions: Eplerenone; Drug
Lead sponsor: Anna Stanhewicz, PhD; Other
Eligibility: 18 Years to 45 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Breastfeeding, Postpartum Sexual Dysfunction, Vaginal Atrophy
Interventions: Estradiol, Vaginal Moisturizer; Drug · Device
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Parkinson Disease
Interventions: Neural recordings and stimulation; Device
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 40 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: HIV Infections
Interventions: FDA Approved Antiretroviral Therapy (see list below); Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 5
States / cities: San Diego, California • San Francisco, California • Baltimore, Maryland + 2 more

Conditions: Circulatory Shock, Cardiovascular Shock
Interventions: Nitroglycerin Topical Product; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 80 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Postoperative Cognitive Dysfunction, Delirium, Dementia, Neurotoxicity
Interventions: Not listed
Lead sponsor: Vanderbilt University; Other
Eligibility: 65 Years to 95 Years
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Mild Cognitive Impairment
Interventions: Progressive aerobic exercise, Adaptive cognitive training, Combined; Behavioral
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 50 Years to 80 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Mild Cognitive Impairment (MCI)
Interventions: Memory Support System, Brain Health Education; Behavioral
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 55 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Hypertension, Female Sexual Dysfunction
Interventions: nebivolol and metoprolol succinate, metoprolol succinate and nebivolol; Drug
Lead sponsor: East Coast Institute for Research; Network
Eligibility: 40 Years and older · Female only
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Subjective Cognitive Concerns, Mild Cognitive Impairment, Mild Behavioral Impairment, Healthy Aging
Interventions: AROMHA Brain Health Test; Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 100 Years
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Mild Cognitive Impairment, Alzheimer Disease
Interventions: lyophilized blueberry supplement; Dietary Supplement
Lead sponsor: Duke University; Other
Eligibility: 55 Years to 85 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Durham, North Carolina

Search by objective public record fields.

Ammonia Levels and Cognitive Impairment

CES1 Carriers in the PAPI Study

Hemp Fiber Ingestion and Gut Permeability After Exercise

A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participants With Early Alzheimer's Disease (ALTITUDE-AD)

A Physical Activity Program Compared to Health Education for Improving Memory and Attention in Hispanic Women With Newly-Diagnosed Stage I-IIIa Breast Cancer, MAMA Trial

Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Facilities

The Women's Urology Center/WISH Database Project

The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial

Study of the Effect of Inhaled Anesthetics on Diastolic Heart Function Using a Doppler-derived Efficiency Index

A Randomized Triple-Blind Placebo-Controlled Study to Evaluate the Effects of a Supplement on Lower Urinary Tract Symptoms in Men.

Evaluating Treatment Continuation in Telehealth Patients Receiving an Automated Patient-Reported Outcome Tool

Efficacy of Vevye Ophthalmic Solution for the Treatment of Meibomian Gland Dysfunction

Role of Endothelial Function in SCI CVD Risk

MR and Inflammation After Preeclampsia

Postpartum Vaginal Estrogen for Breastfeeding Patients

Neurophysiology Biomarkers of Cognitive Impairment Associated With Deep Brain Stimulation

Clinical Trial of CNS-targeted HAART (CIT2)

Physiologic Effect of Topical Nitroglycerin on Microcirculation Capacity in Patients With Circulatory Shock.

Peri-Anesthetic Imaging of Cognitive Dysfunction

Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment

Memory Support System for Older Chinese Americans With Mild Cognitive Impairment

Comparative Effects of Nebivolol and Metoprolol on Female Sexual Function

Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD

Effect of Blueberry Supplementation on Alzheimer's Biomarkers