Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 8, 2026, 11:13 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 769–792 of 3,978 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Pathophysiology Clear all

Conditions: Upper Extremity Dysfunction, Traumatic Brain Injury
Interventions: Active High-definition Transcranial Direct Current Stimulation (HD-tDCS), MusicGlove; Device
Lead sponsor: Kessler Foundation; Other
Eligibility: 18 Years to 75 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: West Orange, New Jersey

Conditions: Vulvovaginal Atrophy, Menopause, Dyspareunia, Painful Intercourse
Interventions: Estradiol, Placebo; Drug
Lead sponsor: TherapeuticsMD; Industry
Eligibility: 40 Years to 75 Years · Female only
Enrollment: 764 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 100
States / cities: Huntsville, Alabama • Montgomery, Alabama • Mesa, Arizona + 85 more

Conditions: Depressive Disorder, Major
Interventions: vortioxetine (Lu AA21004), Duloxetine, Placebo; Drug
Lead sponsor: Takeda; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 602 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 62
States / cities: Tucson, Arizona • Little Rock, Arkansas • Bellflower, California + 59 more

Conditions: Septic Shock
Interventions: Not listed
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 1 Month to 18 Years
Enrollment: 389 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 11
States / cities: Phoenix, Arizona • Los Angeles, California • Washington D.C., District of Columbia + 7 more

Conditions: Myocardial Infarction
Interventions: Aliskiren, placebo; Drug
Lead sponsor: Novartis; Industry
Eligibility: 18 Years and older
Enrollment: 820 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Novartis US, New Jersey

Conditions: Coronary Microvascular Dysfunction, Coronary Microvascular Disease, Microvascular Coronary Artery Disease
Interventions: CLBS16, Placebo; Biological
Lead sponsor: Lisata Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 7
States / cities: Los Angeles, California • Gainesville, Florida • Hollywood, Florida + 4 more

Conditions: Alzheimer's Disease, Mild Cognitive Impairment
Interventions: Active Lighting Intervention, Control Lighting Intervention; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 55 Years and older
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Menands, New York • New York, New York

Conditions: Gastrointestinal Dysfunction
Interventions: Neostigmine, Glycopyrrolate, Saline (Placebo), High Resolution Colonic Manometry; Drug · Other · Device
Lead sponsor: James J. Peters Veterans Affairs Medical Center; Federal
Eligibility: 18 Years to 75 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Dry Eye, Meibomian Gland Dysfunction
Interventions: TearCare, LipiFlow; Device
Lead sponsor: Sight Sciences, Inc.; Industry
Eligibility: 22 Years and older
Enrollment: 235 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 10
States / cities: Scottsdale, Arizona • Laguna Hills, California • Newport Beach, California + 7 more

Conditions: Orgasmic Disorder
Interventions: Wellbutrin XL; Drug
Lead sponsor: Segraves, R., T., M.D., Ph.D.; Other
Eligibility: 20 Years to 50 Years · Female only
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Healthy
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: Not listed
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1996 – 2001
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Cholesterol Ester Storage Disease(CESD), Lysosomal Acid Lipase Deficiency, LAL-Deficiency
Interventions: Sebelipase alfa 0.35 mg/kg, Sebelipase alfa 1 mg/kg, Sebelipase alfa 3 mg/kg; Drug
Lead sponsor: Alexion Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 3
States / cities: Stanford, California • New York, New York • Pittsburgh, Pennsylvania

Conditions: SI Joint Pain
Interventions: 0.75% bupivacaine, .75% bupivacaine; Drug
Lead sponsor: SI-BONE, Inc.; Industry
Eligibility: 21 Years to 75 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 7
States / cities: Mount Vernon, Illinois • Lexington, Kentucky • Cleveland, Ohio + 4 more

Conditions: Mild Alzheimer's Disease, Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
Interventions: Monoclonal Antibodies Directed Against Amyloid for the Treatment of Alzheimer's Disease; Drug
Lead sponsor: Centers for Medicare and Medicaid Services/ Coverage and Analysis Group; Federal
Eligibility: Not listed
Enrollment: 8,680 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Obstetric Labour, Premature, Premature Ejaculation
Interventions: GSK221149; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2007
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: Cardiovascular Diseases, Oxidative Stress, Endothelial Dysfunction
Interventions: Nitrogen Gas for Inhalation, Blood withdrawal, Nitric Oxide; Drug · Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Coronary Artery Disease, Endothelial Dysfunction
Interventions: Music therapy; Other
Lead sponsor: Emmanouil Brilakis; Federal
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Alzheimer Disease, Mild Cognitive Impairment, Cognitive Decline
Interventions: Risk Assessment Cognitive Screening; Diagnostic Test
Lead sponsor: University of Texas at Austin; Other
Eligibility: 60 Years and older
Enrollment: 152 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Common Variable Immunodeficiency (CVID), Primary Immune Regulatory Disorder, Immune Dysregulation, DiGeorge Syndrome, STAT 1 Gain of Function, STAT 3 Gain of Function, Hypomorphic RAG1 Deficiency, CD40 Ligand Deficiency, Mendelian Susceptibility to Mycobacterial Disease, GATA2 Associated Immunodeficiency, CD40 Deficiency, Hypomorphic RAG2 Deficiency, Immune Dysregulation Polyendocrinopathy Enteropathy X-Linked Syndrome, Omenn Syndrome, Chronic Granulomatous Disease
Interventions: Hematopoietic stem cell transplant (HSCT); Biological
Lead sponsor: Paul Szabolcs; Other
Eligibility: 5 Years to 40 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Thalassemia, Sickle Cell Disease, Glanzmann Thrombasthenia, Wiskott-Aldrich Syndrome, Chronic-granulomatous Disease, Severe Congenital Neutropenia, Leukocyte Adhesion Deficiency, Schwachman-Diamond Syndrome, Diamond-Blackfan Anemia, Fanconi Anemia, Dyskeratosis-congenita, Chediak-Higashi Syndrome, Severe Aplastic Anemia
Interventions: Alefacept; Drug
Lead sponsor: Emory University; Other
Eligibility: Up to 21 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Chronic Kidney Disease
Interventions: Immediate release sodium nitrite, Isoquercetin, placebos; Drug · Dietary Supplement · Other
Lead sponsor: Tulane University; Other
Eligibility: 21 Years to 74 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Coronary Microvascular Dysfunction, Ischemic Non-Obstructive Coronary Artery Disease
Interventions: CardioFlux; Device
Lead sponsor: Genetesis Inc.; Industry
Eligibility: 18 Years to 100 Years
Enrollment: 93 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 4
States / cities: Detroit, Michigan • Cincinnati, Ohio • Cleveland, Ohio + 1 more

Conditions: Autism Spectrum Disorder, Autism, Autism Spectral Disorder
Interventions: Autologous MSC isolation, concentration, and cryopreservation of adult mesenchymal stem cells, Fecal Biomicrome Transplantation (FMT), Ketogenic RESET Diet Protocol, Trial combines use of cSVF and MSCs (cryopres) with diet modification and FMT (fecal material Transplant in adult ASD patients, FMT (Fecal Material Tranplantation), Use autologous cSVF + MSCs (cryo) for management of autoimmune component, anti-inflammatory and immune modulation; Procedure · Dietary Supplement · Behavioral + 1 more
Lead sponsor: Black Tie Medical, Inc.; Industry
Eligibility: 10 Years to 90 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 2
States / cities: Hamilton, Montana

Conditions: Cognitive Decline
Interventions: Brain exercise gameplay on a portable electronic device; Device
Lead sponsor: Ohio State University; Other
Eligibility: 60 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Search by objective public record fields.

Targeted Noninvasive Brain Stimulation (T-NIBS) to Improve Hand Motor Functions in Acquired Brain Injury

Estradiol Vaginal Softgel Capsules in Treating Symptoms of Vulvar and Vaginal Atrophy in Postmenopausal Women

Efficacy of Lu AA21004 on Cognitive Dysfunction in Major Depressive Disorder

Life After Pediatric Sepsis Evaluation

Safety and Efficacy of Aliskiren in Post Myocardial Infarction Patients (ASPIRE)

A Placebo-Controlled Trial of CLBS16 in Subjects With Coronary Microvascular Dysfunction

Investigating the Impact of Duration and Amount of Light on the Circadian System Response - Aim 3

Use of High Resolution Colonic Manometry in Studying Motility

TearCare System to Treat Dry Eye Disease

Female Orgasmic Disorder (FOD) and Wellbutrin XL

Analysis of Heart Muscle Function Following Exercise in Patients With Heart Disease

Safety, Tolerability and Pharmacokinetics of SBC-102 (Sebelipase Alfa) in Adult Participants With Lysosomal Acid Lipase Deficiency

Validity and Reliability of Diagnostic Findings of SI Joint Blocking

Medicare Anti-Aβ mAb Coverage With Evidence Development (CED) Study

A Study To Assess The Pharmacokinetics Of Different Modified Release Formulations Of GSK221149 In Healthy Adult Subjects

Effects of Prolonged Delivery of Nitric Oxide Gas on Plasma Reduction-Oxidation Reactions in Cardiac Surgical Patients

Functional Change in Endothelium After Cardiac cAtheterization, With and Without Music Therapy

Cognitive Screening Made Easy for PCPs

Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)

Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation

Nitrite, Isoquercetin and Endothelial Dysfunction (NICE) Trial

MCG as a Noninvasive Diagnostic Strategy for Suspected Coronary Microvascular Dysfunction

Autism Spectrum Disorder (ASD) Neurodevelopmental Disorder With Issues Social Behavior, Communication Issues, GI Dysfunction. Study is Multimodal Interventions Targeting These Pathways With cSVF, Stored MSCs, FMT and Diet Modification. Role of Autoimmunity, Gut-brain Issues, & Issues Examined.

Preoperative Cognitive Reserve in Older Surgical Patients: A Feasibility Study