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Showing 1–24 of 36 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Perfusion Pressures Clear all
Terminated Not applicable Interventional Results available

Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion (4hour)

NCT02388880
View directory record Official record
Conditions
Head Injury, Intracranial Pathology, Compromised Cerebral Perfusion
Interventions
ITPR
Device
Lead sponsor
Advanced Circulatory Systems
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 21, 2019 · Synced Sep 6, 2026, 6:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

AI-Guided Predictions of Blood Pressure Dysregulation Using Perfusion Index as a Novel Biomarker in Persons With Spinal Cord Injury

NCT07699094
View directory record Official record
Conditions
Spinal Cord Injuries (SCI), Blood Pressure, Thermoregulation, Perfusion Index
Interventions
Controlled Cool Thermal Challenge (18°C)
Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 6, 2026, 6:48 AM EDT
Completed No phase listed Observational

Diurnal and Nocturnal Effect of Travatan With SofZia Preservative on Intraocular Pressure and Ocular Perfusion Pressure

NCT01779778
View directory record Official record
Conditions
Open Angle Glaucoma, Ocular Hypertension
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 1, 2016 · Synced Sep 6, 2026, 6:48 AM EDT
Terminated No phase listed Observational

Effects of Nitrous Oxide on Intraocular Pressure

NCT00696189
View directory record Official record
Conditions
Post Operative Visual Loss
Interventions
Not listed
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 23, 2015 · Synced Sep 6, 2026, 6:48 AM EDT
Completed Early Phase 1 Interventional

Real-Time Decision Support for Improving Intraoperative Cerebral Perfusion Pressure

NCT03285971
View directory record Official record
Conditions
Cerebral Hypoperfusion
Interventions
Electronic CPP pager alert
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 11, 2022 · Synced Sep 6, 2026, 6:48 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

The Effect of Nitroglycerin Ointment, Fluorescent Angiography, and Incisional Negative Pressure Wound Therapy on Mastectomy Skin Flap Perfusion-Related Problems

NCT03716050
View directory record Official record
Conditions
Perfusion; Complications
Interventions
Nitroglycerin, Negative Pressure Wound Therapy/ Wound VAC, Fluorescent Angiography with indocyanine-green (not to exceed 5mg/kg), No treatment
Drug · Device · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Sep 6, 2026, 6:48 AM EDT
Completed No phase listed Observational

Comparative Analysis of Cerebral Oximetry and Mean Arterial Pressures at the Cerebral Level in the Beach Chair Position

NCT01645982
View directory record Official record
Conditions
Cerebral Perfusion
Interventions
Not listed
Lead sponsor
Paul Papagni
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Sep 6, 2026, 6:48 AM EDT
Completed Not applicable Interventional

Effects of Head Elevation on Intracranial Pressure in Children

NCT00636376
View directory record Official record
Conditions
Head Injury
Interventions
Place HOB in alternate positions from 0-50 degrees.
Procedure
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 18 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 20, 2008 · Synced Sep 6, 2026, 6:48 AM EDT
Active, not recruiting Phase 2 Interventional

Impact of Intensive Treatment of SBP on Brain Perfusion, Amyloid, and Tau (IPAT Study)

NCT05331144
View directory record Official record
Conditions
Cognitively Normal Older Adults, Hypertension, Subjective Cognitive Decline, Family History of Dementia
Interventions
Angiotensin II Receptor Blockers (ARBs, losartan) and Calcium Channel Blockers (CCB, amlodipine), PCP
Drug · Other
Lead sponsor
Rong Zhang
Other
Eligibility
60 Years to 85 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 6, 2026, 6:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

NATO Litter: Fluid Immersion System (FIS) Versus Traditional Mattress for Pressure Dispersion

NCT03483623
View directory record Official record
Conditions
Pressure Distribution, Military Litters, Peak Pressure Index, Total Surface Area, Tissue Perfusion
Interventions
NATO WELP combination, NATO FIS combination, RAVEN WELP combination, RAVEN FIS combination
Other
Lead sponsor
David Grant U.S. Air Force Medical Center
Federal
Eligibility
19 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Travis Air Force Base, California
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Sep 6, 2026, 6:48 AM EDT
Not listed Phase 2 Interventional

IRB-HSR# 14299: The Use of the Intrathoracic Pressure Regulator (ITPR) to Improve Cerebral Perfusion Pressure in Patients With Altered Intracranial Elastance

NCT01205607
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
ITPR -5 mm Hg then -9 mm Hg, ITPR -9 & then -5mm Hg
Device
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 19, 2010 · Synced Sep 6, 2026, 6:48 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Pain Reduction and Ovarian Perfusion Following Uterine Fibroid Embolization

NCT06106633
View directory record Official record
Conditions
Uterine Bleeding, Uterine Fibroid
Interventions
TriNaV
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Sep 6, 2026, 6:48 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients

NCT01501929
View directory record Official record
Conditions
Hypertension
Interventions
Metoprolol succinate, Nebivolol, Non-invasive measurement of Cardiac Output (CO), Endothelial cell collection, Microvascular perfusion assessment using Definity
Drug · Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 5, 2018 · Synced Sep 6, 2026, 6:48 AM EDT
Terminated Phase 1Phase 2 Interventional

PEEP and V/Q Mismatch in Premature Infants

NCT03109613
View directory record Official record
Conditions
Respiratory Insufficiency Syndrome of Newborn, Infant, Premature, Diseases
Interventions
Positive end-expiratory pressure (PEEP)
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
0 Days to 28 Days
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
3
States / cities
Newark, Delaware • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Sep 6, 2026, 6:48 AM EDT
Completed Phase 4 Interventional Results available

Circadian Ocular Perfusion Pressure and Ocular Blood Flow

NCT00800540
View directory record Official record
Conditions
Glaucoma
Interventions
Brinzolamide 10 mg/ml/Timolol 5 mg/ml eye drops suspension, Brimonidine 20 mg/ml/Timolol 5 mg/ml eye drops solution
Drug
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Mar 21, 2013 · Synced Sep 6, 2026, 6:48 AM EDT
Terminated Not applicable Interventional

Targeting Abdominal Perfusion Pressure in Septic Shock

NCT03582046
View directory record Official record
Conditions
Acute Kidney Injury, Septic Shock, Resuscitations
Interventions
Abdominal Perfusion Pressure (APP), Mean Arterial Pressure (MAP)
Device
Lead sponsor
Potrero Medical
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
Little Rock, Arkansas • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Sep 6, 2026, 6:48 AM EDT
Recruiting Not applicable Interventional

Ventilator Pressure and Optimization of Compliance and Hemodynamics

NCT06512935
View directory record Official record
Conditions
Bronchopulmonary Dysplasia, Pulmonary Hypertension Due to Lung Diseases and Hypoxia, Extreme Prematurity, Ventilator Lung; Newborn, Ventilation Perfusion Mismatch
Interventions
Increase in the PEEP followed by decrease in the PEEP, Decrease in the PEEP followed by increase in the PEEP
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
7 Days to 30 Days
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 6, 2026, 6:48 AM EDT
Completed Not applicable Interventional Results available

Vasopressin Versus Catecholamines for Cerebral Perfusion Pressure Control in Brain Injured Trauma Patients

NCT00795366
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
arginine vasopressin, Standard catecholamine
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 11, 2014 · Synced Sep 6, 2026, 6:48 AM EDT
Completed Not applicable Interventional Results available

Comparison of Nasal and Forehead Oximetry in Critically Ill Patients at Risk for Decreased Peripheral Perfusion

NCT02382133
View directory record Official record
Conditions
Hypotension, Pressure Ulcer
Interventions
Nasal alar oxygen sensor
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 90 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 6, 2017 · Synced Sep 6, 2026, 6:48 AM EDT
Terminated Not applicable Interventional

POMCO2 Clinical Study MicroTrend System pCO2 Sensor

NCT05499624
View directory record Official record
Conditions
Hypoperfusion
Interventions
MicroTrend System
Device
Lead sponsor
ExoStat Medical, Inc.
Industry
Eligibility
22 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
North Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 9, 2023 · Synced Sep 6, 2026, 6:48 AM EDT
Completed No phase listed Observational

The Diurnal and Nocturnal Effect of Simbrinza and Timolol on Intraocular Pressure and Ocular Perfusion Pressure

NCT02165631
View directory record Official record
Conditions
Open Angle Glaucoma, Ocular Hypertension, Pigment Dispersion Syndrome, Pseudoexfoliation Glaucoma
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 13, 2016 · Synced Sep 6, 2026, 6:48 AM EDT
Not yet recruiting Not applicable Interventional

Intraabdominal Pressure Monitoring Urinary Catheter and Kidney Perfusion Pressure

NCT06989762
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Conventional Foley Catheter(Medline), Accuryn Foley Catheter
Device
Lead sponsor
Dang Tan Phat
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2025 · Synced Sep 6, 2026, 6:48 AM EDT
Completed Not applicable Interventional Results available

Impact of CPAP Level on V/Q Mismatch in Premature Infants

NCT02983825
View directory record Official record
Conditions
Infant, Premature, Diseases, Respiratory Insufficiency Syndrome of Newborn
Interventions
Continuous positive airway pressure (CPAP); level changes
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
24 Hours to 35 Weeks
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2021 · Synced Sep 6, 2026, 6:48 AM EDT
Completed Not applicable Interventional Results available

The Effects of an Antioxidant Formulation on Ocular Blood Flow

NCT01930487
View directory record Official record
Conditions
Primary Open Angle Glaucoma
Interventions
dietary supplement with antioxidants, Placebo
Dietary Supplement
Lead sponsor
ScienceBased Health
Industry
Eligibility
30 Years to 70 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 4, 2016 · Synced Sep 6, 2026, 6:48 AM EDT