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ClinicalTrials.gov public records Last synced Oct 23, 2026, 9:06 AM EDT

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Showing 1–24 of 33 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Peri-Implantitis Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Assessment of the Effects of Different Implant Abutment Occluding Materials on Dental Implant Health Parameters and Microbiology

NCT02625597
View directory record Official record
Conditions
Peri-Implantitis, Dental Implant Failed, Dental Implant Failure Nos
Interventions
Cotton Pellet, Polytetrafluoroethylene Tape, Synthetic Foam, Polyvinylsiloxane
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Dec 9, 2015 · Synced Oct 23, 2026, 9:06 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Zirconia Implants: Practice-based Evidence

NCT06314425
View directory record Official record
Conditions
Dental Implants, Ceramic Implant
Interventions
Immediate dental implants placements on fresh sockets after tooth extraction
Procedure
Lead sponsor
Swiss Dental Solutions
Industry
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Englewood Cliffs, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 23, 2026, 9:06 AM EDT
Completed Phase 3 Interventional Results available

Antibiotic Study for Dental Implants

NCT00662532
View directory record Official record
Conditions
Periodontitis
Interventions
Minocycline HCl
Drug
Lead sponsor
OraPharma
Industry
Eligibility
21 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
4
States / cities
Aurora, Colorado • Ann Arbor, Michigan • Hazlet, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2011 · Synced Oct 23, 2026, 9:06 AM EDT
Completed Phase 3 Interventional

Arestin - Use in Subjects With Peri-Implantitis

NCT01539564
View directory record Official record
Conditions
Peri-Implantitis
Interventions
Minocycline HCl Microspheres
Drug
Lead sponsor
OraPharma
Industry
Eligibility
21 Years and older
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
9
States / cities
Los Angeles, California • Gainsville, Florida • Augusta, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2014 · Synced Oct 23, 2026, 9:06 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty

NCT06063876
View directory record Official record
Conditions
Peri-implant Mucositis, Peri-Implantitis
Interventions
Induction of experimental peri-implant mucositis, Resolution of experimental peri-implant mucositis
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 23, 2026, 9:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Cortical Shield for Facial Bone Reconstruction

NCT04827693
View directory record Official record
Conditions
Tooth Loss, Tooth Diseases, Tooth Fracture, Tooth Injuries, Periodontal Bone Loss, Periodontitis, Peri-Implantitis, Tooth Decay
Interventions
Not listed
Lead sponsor
Verdugo, Fernando, DDS
Individual
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 23, 2026, 9:06 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Immediate Implant Outcomes With and Without Bone Augmentation

NCT05157009
View directory record Official record
Conditions
Tooth Loss, Bone Loss, Alveolar, Dental Diseases, Dental Trauma
Interventions
implant placement
Procedure
Lead sponsor
Verdugo, Fernando, DDS
Individual
Eligibility
20 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Gabriel, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Oct 23, 2026, 9:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Comparison of Inflammatory Mediators Surrounding Titanium or Zirconium Implant Abutments

NCT01870349
View directory record Official record
Conditions
Peri-implantitis
Interventions
Gingival Crevicular Fluid Sampling
Procedure
Lead sponsor
Christopher Barwacz
Other
Eligibility
18 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 27, 2018 · Synced Oct 23, 2026, 9:06 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Intaglio Surface of Full-arch Implant Supported Prosthesis

NCT06636097
View directory record Official record
Conditions
Peri-Implantitis
Interventions
Full arch
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 23, 2026, 9:06 AM EDT
Enrolling by invitation Not applicable Interventional

Regenerative Treatment of Peri-implantitis

NCT06153212
View directory record Official record
Conditions
Peri-Implantitis
Interventions
Membrane placement with bone grafting
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 23, 2026, 9:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Role of Functional Epigenetic Modifications in Peri-Implantitis

NCT03753464
View directory record Official record
Conditions
Periimplantitis
Interventions
Gingival biopsy and blood sample collection
Procedure
Lead sponsor
NYU College of Dentistry
Other
Eligibility
20 Years to 90 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 23, 2026, 9:06 AM EDT
Completed Not applicable Interventional Results available

Efficacy of Er:YAG Laser in Decontamination of Dental Implants: An In-Vitro Study

NCT03100435
View directory record Official record
Conditions
Peri-Implantitis
Interventions
Er:YAG Laser, Carbon Fiber Curette
Device · Other
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 31, 2023 · Synced Oct 23, 2026, 9:06 AM EDT
Completed Early Phase 1 Interventional

Antiseptic Effects on the Dental Implant Internal Surface Microbiome

NCT05024760
View directory record Official record
Conditions
Peri-Implantitis, Peri-implant Mucositis, Implant Infection, Dental Implant Failed
Interventions
Chlorhexidine, Hydrogen Peroxide
Drug
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years to 55 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 23, 2026, 9:06 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effect of Obesity on Oral Peri-implant Health - A Cross-Sectional Study

NCT01878071
View directory record Official record
Conditions
Obesity, Peri-implant Inflammation, Peri-implantitis
Interventions
Not listed
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2012
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 20, 2014 · Synced Oct 23, 2026, 9:06 AM EDT
Recruiting Not applicable Interventional

Immediate Versus Delayed Surgical Reconstruction of Peri-implantitis Intra-bony Defects.

NCT07325747
View directory record Official record
Conditions
Peri Implantitis
Interventions
Staged peri-implant debridement and regeneration, Simultaneous peri-implant debridement and regeneration
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 23, 2026, 9:06 AM EDT
Terminated Not applicable Interventional Results available

Efficacy of Synthetic Bone Graft for Treatment of Peri-implantitis

NCT03213210
View directory record Official record
Conditions
Peri-Implantitis
Interventions
easy-graft CLASSIC (beta-Tricalcium Phosphate)
Device
Lead sponsor
Sunstar Americas
Industry
Eligibility
21 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 23, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Peri-implantitis Treatment: Clinical Results of Conventional Treatment vs. the Addition of Biolase

NCT03544515
View directory record Official record
Conditions
Peri-Implantitis
Interventions
Er,Cr:YSGG laser, Scaling, Inactive Er,Cr:YSGG
Device · Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 9, 2024 · Synced Oct 23, 2026, 9:06 AM EDT
Recruiting No phase listed Observational

Serum Inflammatory Protein Concentration During Dental Treatment

NCT07468929
View directory record Official record
Conditions
Periodontal Disease, Periodontal Surgery
Interventions
Blood samples for inflammatory markers, periodontal surgery, Periodontal maintenance, Non-surgical deep cleaning
Other · Procedure
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 23, 2026, 9:06 AM EDT
Terminated No phase listed Observational

Clinical Outcomes of Resective Surgical Treatment of Peri-Implantitis With or Without Implantoplasty

NCT04259840
View directory record Official record
Conditions
Peri-Implantitis
Interventions
Observation
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
41 participants
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Oct 23, 2026, 9:06 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Incidence of Bleeding on Probing as an Indicator of Peri-Implant Disease Progression

NCT06033859
View directory record Official record
Conditions
Peri-Implantitis, Bleeding of Subgingival Space
Interventions
Clinical measurements, Radiographic measurement, Dental prophylaxis or maintenance
Diagnostic Test · Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 80 Years
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 23, 2026, 9:06 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Laser Therapy Treatment of Peri-implantitis.

NCT01972399
View directory record Official record
Conditions
Peri-implantitis
Interventions
Laser, Mechanical debridement
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 3, 2015 · Synced Oct 23, 2026, 9:06 AM EDT
Completed Phase 3 Interventional

Arestin - Use in Subjects With Peri-Implantitis (With Subgingival Microbiological Evaluation)

NCT01517334
View directory record Official record
Conditions
Peri-Implantitis
Interventions
Minocycline HCl Microspheres
Drug
Lead sponsor
OraPharma
Industry
Eligibility
21 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
10
States / cities
Baltimore, Maryland • Boston, Massachusetts • Ann Arbor, Michigan + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2015 · Synced Oct 23, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dental Hygiene and Peri-Implant Tissues Homeostasis Ancillary Study

NCT03917264
View directory record Official record
Conditions
Peri-Implantitis
Interventions
Peri-implantitis debridement, Dental hygiene procedures
Procedure · Other
Lead sponsor
University of Washington
Other
Eligibility
25 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
2
States / cities
San Antonio, Texas • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Oct 23, 2026, 9:06 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Surgical Treatment of Peri-implantitis Using a Bone Substitute With or Without a Resorbable Collagen Membrane

NCT05699343
View directory record Official record
Conditions
Peri-Implantitis, Surgery
Interventions
InterOss Collagen (Bone xenograft) and InterOss Collagen Guide (Collagen membrane), InterOss Collagen (Bone xenograft)
Procedure
Lead sponsor
Andrea Ravida
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 23, 2026, 9:06 AM EDT