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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Perinatal Asphyxia Clear all
Recruiting Not applicable Interventional

Pathways to Perinatal Mental Health Equity

NCT06790641
View directory record Official record
Conditions
Perinatal Anxiety, Perinatal Depression, Social Determinants of Health (SDOH), Peer Support, Obstetric Care, Substance Use Disorder (SUD), Perinatal Depression, Substance Use
Interventions
Program in Support of Moms (PRISM), PSI Peer Support
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 70 Years
Enrollment
1,270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Shrewsbury, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 22, 2026, 10:19 AM EDT
Recruiting Not applicable Interventional

Accelerated TMS for Perinatal Depression

NCT06968390
View directory record Official record
Conditions
Perinatal Depression, Post Partum Depression, Major Depressive Disorder
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Sep 22, 2026, 10:19 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Topiramate in Neonates Receiving Whole Body Cooling for Hypoxic Ischemic Encephalopathy

NCT01765218
View directory record Official record
Conditions
Hypoxic Ischemic Encephalopathy
Interventions
Topiramate, Placebo
Drug
Lead sponsor
Kristin R Hoffman
Other
Eligibility
Up to 6 Hours
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional

Online Collaborative Learning Intervention to Prevent Perinatal Depression

NCT02121015
View directory record Official record
Conditions
Depression, Postpartum
Interventions
Share, Self-Directed
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Chicago, Illinois • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional

Baby2Home (B2H) Mobile Health Application

NCT05595486
View directory record Official record
Conditions
COVID-19 Pandemic, Health Knowledge, Attitudes, Practice, Perinatal Depression, Mental Health Wellness, Post Partum Depression
Interventions
Baby2Home Mobile Application
Other
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older
Enrollment
642 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Chicago, Illinois • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional

Integrated Chronotherapy for Perinatal Depression

NCT02053649
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Postpartum Depression
Interventions
Triple Chronotherapy, Usual Care
Behavioral · Other
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 28, 2019 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Phase 1 Interventional

Sober Network IPT for Perinatal Women With Comorbid Substance Use and Depression

NCT01550913
View directory record Official record
Conditions
Perinatal Depression, Substance Use
Interventions
Sober Network Interpersonal Psychotherapy (IPT), Treatment as Usual
Behavioral · Other
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 29, 2016 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional

Care Managers for Perinatal Depression (CMPD)

NCT01773629
View directory record Official record
Conditions
Depression, Pregnancy
Interventions
Intervention, Control
Other
Lead sponsor
Lancaster General Hospital
Other
Eligibility
13 Years and older · Female only
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
4
States / cities
Lancaster, Pennsylvania • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 29, 2014 · Synced Sep 22, 2026, 10:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing "Doula Link", a Multi-Component Intervention to Improve Perinatal Mental Health

NCT07217561
View directory record Official record
Conditions
Perinatal Depression, Perinatal Anxiety
Interventions
Doula Link
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
Not listed
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 22, 2026, 10:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Esophageal Motility and Airway Defenses Among Infants

NCT00062452
View directory record Official record
Conditions
Infant, Premature, Diseases, Congenital Abnormalities, Perinatal Asphyxia
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
2 Weeks to 6 Months
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Phase 2 Interventional

Use of Omega-3 Fatty Acids for Perinatal Depression

NCT00402389
View directory record Official record
Conditions
Depression, Depression, Postpartum
Interventions
Omega-3 Fatty Acids (EPA plus DHA), Supportive psychotherapy, Placebo
Drug · Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 28, 2013 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating the Effectiveness of Brief Interpersonal Psychotherapy for Pregnant Women With Depression

NCT00292903
View directory record Official record
Conditions
Depression
Interventions
Brief interpersonal psychotherapy, Facilitated referral for treatment as usual
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 9, 2012 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional

Behavioral Activation for Perinatal Depression

NCT01401231
View directory record Official record
Conditions
Depression During Pregnancy
Interventions
Behavioral activation psychotherapy, Usual care
Behavioral · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older · Female only
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Sep 22, 2026, 10:19 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression

NCT06746337
View directory record Official record
Conditions
Depression During Pregnancy, Depression, Postpartum
Interventions
IMAGINE
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
16 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Integrating Text Messages Into the Mothers and Babies Course

NCT03420755
View directory record Official record
Conditions
Perinatal Depression, Postpartum Depression
Interventions
Mothers and Babies 1-on-1, Mothers and Babies Plus Text
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
16 Years and older · Female only
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 14, 2019 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model

NCT04051320
View directory record Official record
Conditions
Perinatal Depression, Post Partum Depression, Depression, Postpartum, Depression
Interventions
Leuprolide Acetate 3.75 MG/ML, Estradiol 2 Mg tablet, Micronized progesterone
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
22 Years to 45 Years · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 24, 2023 · Synced Sep 22, 2026, 10:19 AM EDT
Recruiting Not applicable Interventional

Feasibility and Acceptability of a Novel Cognitive Behavioral Skills Mobile App for Pregnant and Postpartum Individuals

NCT05897619
View directory record Official record
Conditions
Perinatal Anxiety, Perinatal Depression
Interventions
Experimental: Maya Perinatal Cognitive Behavioral Skills App
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Online Intervention to Prevent Perinatal Depression and Promote Breastfeeding

NCT04128202
View directory record Official record
Conditions
Depression, Breastfeeding
Interventions
Sunnyside, Sunnyside Plus
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 25, 2021 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Augmented Infant Resuscitator (AIR): Transitioning a Novel Behavior Change Innovation to Drive Newborn Ventilation Skills Enhancement

NCT05349175
View directory record Official record
Conditions
Asphyxia Neonatorum, Birth Asphyxia, Perinatal Asphyxia
Interventions
Augmented Infant Resuscitator (AIR)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Center M: Digital Health Innovation Pilot

NCT06000449
View directory record Official record
Conditions
Perinatal Depression
Interventions
Center M, Treatment as Usual
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Sep 22, 2026, 10:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Labor Pain and Postpartum Behavioral Health Outcomes Study

NCT02692404
View directory record Official record
Conditions
Depression, Postpartum, Pregnancy, Child Development, Pain, Labor Pain
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
199 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional

The Staying Well Study: An Open Trial of Mindfulness-Based Cognitive Therapy for the Prevention of Perinatal Depression

NCT02391870
View directory record Official record
Conditions
Pregnancy, Depression, Postpartum Depression
Interventions
MBCT-PD
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years and older · Female only
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
4
States / cities
Boulder, Colorado • Denver, Colorado • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 5, 2020 · Synced Sep 22, 2026, 10:19 AM EDT
Terminated No phase listed Observational

Novel Epidermal Recording and Detection of Seizures

NCT02451618
View directory record Official record
Conditions
Seizures, Encephalopathy, Asphyxiated Newborn
Interventions
Not listed
Lead sponsor
Sharp HealthCare
Other
Eligibility
1 Day and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 6, 2018 · Synced Sep 22, 2026, 10:19 AM EDT
Completed Not applicable Interventional Results available

Scaling Up Maternal Mental Healthcare by Increasing Access to Treatment (SUMMIT)

NCT04153864
View directory record Official record
Conditions
Perinatal Depression
Interventions
Brief Behavioral Activation Treatment
Behavioral
Lead sponsor
Mount Sinai Hospital, Canada
Other
Eligibility
18 Years and older · Female only
Enrollment
1,230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Evanston, Illinois • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Sep 22, 2026, 10:19 AM EDT