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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed No phase listed Observational Accepts healthy volunteers

Sonographic Imaging of Oral and Dental Anatomical Structures (A Pilot Study)

NCT03657589
Conditions
Ultrasound, Oral Mucosa, Gingival Recession, Alveolar Bone Loss
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed No phase listed Observational Accepts healthy volunteers

A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health

NCT05594004
Conditions
Gingivitis, Dental Plaque
Interventions
Oscillating-rotating electric toothbrush, Sonic electric toothbrush, Manual toothbrush
Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
2,929 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Completed Phase 1 Interventional Accepts healthy volunteers

Exploratory Study of Iocide Oral Rinse in a Diabetic Population

NCT00801164
Conditions
Diabetes Type 2, Periodontitis
Interventions
Frio Mouth Rinse Placebo, Frio Mouth Rinse
Drug
Lead sponsor
Biomedical Development Corporation
Industry
Eligibility
35 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
San Antonio, Texas
Completed Phase 1 Interventional Accepts healthy volunteers

Next Science Antimicrobial Mouth Rinse Study

NCT03154021
Conditions
Gingivitis, Dental Plaque
Interventions
Next Science OTC Oral Rinse with Essential Oils, OTC Oral Rinse Control
Combination Product
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 60 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
2
States / cities
Gainesville, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Utilization of a Periodontal Endoscope in Nonsurgical Periodontal Therapy

NCT05293301
Conditions
Periodontitis, Adult
Interventions
Use of Periodontal Endoscope (Perioscopy®) to enhance visualization while performing teeth deep cleaning, Use of traditional loupes to enhance magnification to enhance visualization while performing teeth deep cleaning
Device
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Orleans, Louisiana
Conditions
Periodontal Diseases
Interventions
Periodontal Treatment
Procedure
Lead sponsor
The Forsyth Institute
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2004
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Periodontal Diseases
Interventions
Periodontal Structure Repair (PSR), Standard Root Planing
Device
Lead sponsor
Periovance, Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
4
States / cities
Birmingham, Alabama • Cambridge, Massachusetts • Stony Brook, New York + 1 more
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness

NCT07053969
Conditions
Dental Implantation, Missing Teeth, Periodontitis, Adult, Mucositis
Interventions
Enamel Matrix Derivative
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 18 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Peri-Implantitis
Interventions
Observation
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
41 participants
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Evaluate Inflammation Caused by Gingivitis in Adults

NCT00941668
Conditions
Gingivitis
Interventions
Triclosan/Copolymer/fluoride toothpaste, sodium monofluorophosphate toothpaste
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 60 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Cardiovascular Disease, Coronary Heart Disease, Myocardial Infarction, Cerebrovascular Accident
Interventions
Periodontal Treatment: SRP, Referral
Procedure
Lead sponsor
University at Buffalo
Other
Eligibility
Up to 75 Years
Enrollment
303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Peri-Implantitis
Interventions
Minocycline HCl Microspheres
Drug
Lead sponsor
OraPharma
Industry
Eligibility
21 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
10
States / cities
Baltimore, Maryland • Boston, Massachusetts • Ann Arbor, Michigan + 7 more
Conditions
Dehiscence, Tooth Extraction, Alveolar Bone Loss
Interventions
Minimally Invasive tooth extraction, Alveolar ridge preservation with ABCC, Resorbable collagen membrane (InterCollagen® Guide)
Procedure · Device
Lead sponsor
Debora Dias
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Assessing Gingivitis and Plaque From a Marketed Toothpaste

NCT07158112
Conditions
Gingivitis
Interventions
Stannous Fluoride Dentifrice, Test Stannous Fluoride Dentifrice, Sodium monofluorophosphate dentifrice
Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Whitter, California
Completed Not applicable Interventional Accepts healthy volunteers

Dental Hygiene and Peri-Implant Tissues Homeostasis

NCT03384446
Conditions
Peri-Implantitis
Interventions
Tooth-borne treatment, Implant-specific treatment
Other
Lead sponsor
University of Washington
Other
Eligibility
25 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
2
States / cities
San Antonio, Texas • Seattle, Washington
Conditions
Allogeneic Stem Cell Transplantation
Interventions
Xylitol, Placebo
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
4 Months to 25 Years
Enrollment
419 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Aurora, Colorado • Boston, Massachusetts • Cincinnati, Ohio
Conditions
Periodontal Diseases
Interventions
Artificial Intelligence Application
Behavioral
Lead sponsor
McGuire Institute
Industry
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Timeline
2021 – 2023
U.S. locations
2
States / cities
La Vista, Nebraska • Houston, Texas
Conditions
Dental Plaque
Interventions
19416-154-1, W002194-0221P
Device
Lead sponsor
Johnson & Johnson Consumer and Personal Products Worldwide
Industry
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Las Vegas, Nevada
Completed No phase listed Observational Accepts healthy volunteers

Shifts in the Oral Biofilm of Patients With Known Oral Health Risk Factors

NCT02885064
Conditions
Dental Caries, Gingivitis
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
8 Years to 99 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy of the ToothWave -12 Weeks Calculus Study

NCT04092075
Conditions
Gingivitis, Plaque, Calculus, Dental
Interventions
RF-utilizing powered toothbrush, Control placebo with no RF
Device
Lead sponsor
Home Skinovations Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Pain, Postoperative, Gingival Diseases
Interventions
amnion-chorion membrane, Sutures
Device · Procedure
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Not listed Not applicable Interventional Accepts healthy volunteers

Determination of the Safety and Efficacy of a Novel Oral Rinse on Oral Health

NCT04197427
Conditions
Plaque, Gingivitis
Interventions
Experimental Oral Rinse, Placebo
Device
Lead sponsor
You First Services
Industry
Eligibility
18 Years to 75 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Buffalo, New York
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Regenafil Versus Demineralized Freeze Dried Bone Allograft (DFDBA) for Periodontal Defects

NCT00255970
Conditions
Periodontal Diseases
Interventions
DFDBA, Regenafil
Other · Device
Lead sponsor
RTI Surgical
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
2
States / cities
Indianapolis, Indiana • Louisville, Kentucky
Conditions
Periodontitis, Attachment Loss, Periodontal
Interventions
Minimally invasive periodontal therapy with use of Emdogain, Minimally invasive periodontal therapy without the use of Emdogain
Procedure
Lead sponsor
Texas A&M University
Other
Eligibility
30 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas