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ClinicalTrials.gov public records Last synced Oct 12, 2026, 3:29 AM EDT

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Showing 97–120 of 575 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Peripheral Arterial Disease (PAD) Clear all
Completed Phase 3 Interventional

Efficacy/Safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease

NCT00059657
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
Ecraprost in lipid emulsion
Drug
Lead sponsor
Tanabe Pharma Corporation
Industry
Eligibility
40 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
15
States / cities
Phoenix, Arizona • Tucson, Arizona • Glendale, California + 12 more
Source: ClinicalTrials.gov public record
Updated May 19, 2006 · Synced Oct 12, 2026, 3:29 AM EDT
Completed Not applicable Interventional

Local Paclitaxel Delivery for SFA Disease

NCT00821028
View directory record Official record
Conditions
Atherosclerosis, Angioplasty, Peripheral Arterial Disease
Interventions
Paclitaxel
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 80 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 12, 2026, 3:29 AM EDT
Completed Not applicable Interventional Results available

In-Stent Restenosis Post-Approval Study

NCT02542267
View directory record Official record
Conditions
Peripheral Artery Disease, Vascular Disease
Interventions
Gore VIABAHN Endoprosthesis
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
20
States / cities
Miami, Florida • Honolulu, Hawaii • Rockford, Illinois + 16 more
Source: ClinicalTrials.gov public record
Updated Oct 16, 2023 · Synced Oct 12, 2026, 3:29 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing Impacts of Static Magnetic Fields on Peripheral Pulses and Skin Blood Flow

NCT04539704
View directory record Official record
Conditions
Arterial Stiffness, Magnetic Field Exposure, Peripheral Arterial Disease
Interventions
magnet and sham
Device
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 35 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Davie, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Oct 12, 2026, 3:29 AM EDT
Not listed Not applicable Interventional

External Compression Therapy for Secondary Prevention of Lower-Limb Loss and Cardiovascular Mortality

NCT02054416
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
ArtAssist© Device
Device
Lead sponsor
Temple University
Other
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 8, 2016 · Synced Oct 12, 2026, 3:29 AM EDT
Completed Phase 2 Interventional Results available

Patients With Intermittent Claudication Injected With ALDH Bright Cells

NCT01774097
View directory record Official record
Conditions
Peripheral Artery Disease, Intermittent Claudication
Interventions
ALD-301, Placebo (vehicle)
Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
40 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
9
States / cities
Stanford, California • Gainesville, Florida • Miami, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2017 · Synced Oct 12, 2026, 3:29 AM EDT
Completed Phase 2 Interventional Results available

Hepatocyte Growth Factor to Improve Functioning in PAD

NCT03363165
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
VM202, Placebo
Drug · Other
Lead sponsor
Northwestern University
Other
Eligibility
55 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 30, 2024 · Synced Oct 12, 2026, 3:29 AM EDT
Completed No phase listed Observational

TRanslesIonal Assessment of Gradients During Endovascular Therapy

NCT03163199
View directory record Official record
Conditions
Peripheral Arterial Disease, Fractional Flow Reserve, Hemodynamics
Interventions
Translesional Hemodynamic Measurement
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 18, 2022 · Synced Oct 12, 2026, 3:29 AM EDT
Completed No phase listed Observational

Ultrasonic Perfusion Estimation in Calf Muscle

NCT04755335
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Ultrasound
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Oct 12, 2026, 3:29 AM EDT
Completed Phase 1 Interventional Results available

Study of PDA-002 in Subjects With Peripheral Arterial Disease and Diabetic Foot Ulcers

NCT01859117
View directory record Official record
Conditions
Peripheral Arterial Disease, Diabetic Foot Ulcer
Interventions
PDA-002
Biological
Lead sponsor
Celularity Incorporated
Industry
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
12
States / cities
Phoenix, Arizona • Los Angeles, California • Palo Alto, California + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 12, 2026, 3:29 AM EDT
Completed Not applicable Interventional Results available

Chronic Total Occlusion Crossing With the Wildcat Catheter

NCT01174784
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Chronic TOtAl OcclusioN CrossiNg with thE WildCat CatheTer
Device
Lead sponsor
Avinger, Inc.
Industry
Eligibility
19 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
15
States / cities
Birmingham, Alabama • Mesa, Arizona • Phoenix, Arizona + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2020 · Synced Oct 12, 2026, 3:29 AM EDT
Recruiting Phase 3 Interventional

Improving Mobility After Revascularization in Peripheral Artery Disease

NCT06686121
View directory record Official record
Conditions
Peripheral Artery Disease, Intermittent Claudication, Peripheral Vascular Disease, Mobility Limitation, Revascularization
Interventions
Home Based Exercise, Nitrate Rich Beetroot Juice, Attention Control, Placebo Beetroot Juice Without Nitrate
Behavioral · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
8
States / cities
Tucson, Arizona • Downey, California • Tampa, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 12, 2026, 3:29 AM EDT
Active, not recruiting Not applicable Interventional

Far Red Light to Improve Functioning in PAD

NCT06165016
View directory record Official record
Conditions
Peripheral Artery Disease, Peripheral Vascular Disease, Aging, Walking, Difficulty
Interventions
Far red light therapy, Sham light therapy
Device
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Birmingham, Alabama • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 12, 2026, 3:29 AM EDT
Recruiting Not applicable Interventional

Real-World Registry of the Rotarex(TM) Rotational Excisional Atherectomy System (XTRACT Registry)

NCT07016698
View directory record Official record
Conditions
Peripheral Arterial Disease(PAD)
Interventions
Rotarex(TM) Rotational Excisional Atherectomy System
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
22 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Lakeland, Florida • Humble, Texas
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 12, 2026, 3:29 AM EDT
Completed No phase listed Observational

Phoenix Post-Approval Registry - Using the Phoenix Atherectomy Systems

NCT02475200
View directory record Official record
Conditions
Peripheral Arterial Disease, Claudication, Critical Limb Ischemia
Interventions
Atherectomy
Device
Lead sponsor
Volcano Corporation
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
5
States / cities
Tucson, Arizona • Detroit, Michigan • Saginaw, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2020 · Synced Oct 12, 2026, 3:29 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Rivaroxaban in Reducing the Risk of Major Thrombotic Vascular Events in Subjects With Symptomatic Peripheral Artery Disease Undergoing Peripheral Revascularization Procedures of the Lower Extremities

NCT02504216
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Rivaroxaban (Xarelto, BAY59-7939), Rivaroxaban-Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
50 Years and older
Enrollment
6,564 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
105
States / cities
Alexander City, Alabama • Birmingham, Alabama • Fort Payne, Alabama + 91 more
Source: ClinicalTrials.gov public record
Updated Dec 8, 2020 · Synced Oct 12, 2026, 3:29 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Improving Exercise Rehabilitation Efficacy Outcomes Veterans Peripheral Artery Disease

NCT05648630
View directory record Official record
Conditions
Peripheral Artery Disease (D058729), Oxidative Stress (D018384), Inflammation (D007249)
Interventions
PB125, Placebo, Exercise Rehabilitation
Dietary Supplement · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 12, 2026, 3:29 AM EDT
Completed Phase 2 Interventional Results available

Nitrites, Exercise, and Peripheral Arterial Disease

NCT01684930
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Beetroot Juice (Beet-It Stamina Shot) & Supervised Exercise Training, Placebo Comparator Beverage (Beet-It Stamina Shot) & Exercise Training
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
40 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 29, 2017 · Synced Oct 12, 2026, 3:29 AM EDT
Recruiting Phase 3 Interventional

The COCOA-PAD II Trial

NCT04794530
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
cocoa flavanols, placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
55 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
3
States / cities
Chicago, Illinois • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 12, 2026, 3:29 AM EDT
Recruiting Not applicable Interventional

The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)

NCT06321575
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Golazo® Peripheral Atherectomy System (Golazo® Peripheral AS)
Device
Lead sponsor
Nipro Vascular Innovations Americas, Inc
Industry
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
20
States / cities
Scottsdale, Arizona • Merced, California • Fort Lauderdale, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 12, 2026, 3:29 AM EDT
Not listed Phase 4 Interventional

Synergistic Influence of Rivaroxaban on Inflammation and Coagulation Biomarkers in Patients With CAD and PAD on Aspirin Therapy

NCT04059679
View directory record Official record
Conditions
Coronary Artery Disease, Peripheral Artery Disease
Interventions
Rivaroxaban 2.5 Mg Oral Tablet, Aspirin 81 mg
Drug
Lead sponsor
LifeBridge Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 14, 2020 · Synced Oct 12, 2026, 3:29 AM EDT
Recruiting Phase 3 Interventional

Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk

NCT04774159
View directory record Official record
Conditions
Peripheral Arterial Disease, Atherosclerosis of Extremities, Inflammation
Interventions
Colchicine 0.5 MG Oral Tablet, Colchicine-Placebo
Drug
Lead sponsor
Population Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
6,150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
24
States / cities
New Haven, Connecticut • Gainesville, Florida • Tampa, Florida + 19 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 12, 2026, 3:29 AM EDT
Terminated Not applicable Interventional

AcoArt Litos PCB Below-the-knee Global Trial

NCT06330493
View directory record Official record
Conditions
Chronic Limb-Threatening Ischemia
Interventions
PCB, PTA
Device
Lead sponsor
Acotec Scientific Co., Ltd
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
16
States / cities
Concord, California • Fremont, California • New Haven, Connecticut + 12 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 12, 2026, 3:29 AM EDT
Terminated No phase listed Observational

The Cardiovascular Multi-dimensional Observational Investigation of the Use of PCSK9 Inhibitors (cvMOBIUS)

NCT04197453
View directory record Official record
Conditions
ASCVD
Interventions
Not listed
Lead sponsor
Amgen
Industry
Eligibility
40 Years to 99 Years
Enrollment
752 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
143
States / cities
Birmingham, Alabama • Gilbert, Arizona • Tucson, Arizona + 126 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2021 · Synced Oct 12, 2026, 3:29 AM EDT