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ClinicalTrials.gov public records Last synced Oct 14, 2026, 11:38 AM EDT

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Showing 289–312 of 574 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Peripheral Artery Disease (PAD) Clear all
Completed Phase 1Phase 2 Interventional

ALD-301 for Critical Limb Ischemia, Randomized Trial

NCT00392509
View directory record Official record
Conditions
Critical Limb Ischemia, Peripheral Arterial Disease, Peripheral Vascular Disease
Interventions
ALDH-br bone marrow cells vs. mononuclear bone marrow cells
Procedure
Lead sponsor
Aldagen
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
5
States / cities
Birmingham, Alabama • Atlanta, Georgia • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated May 14, 2009 · Synced Oct 14, 2026, 11:38 AM EDT
Completed Phase 1Phase 2 Interventional

Safety, Efficacy, and Pharmacokinetics (PK) Study of Trans Sodium Crocetinate (TSC) in Patients With Intermittent Claudication

NCT00725881
View directory record Official record
Conditions
Intermittent Claudication
Interventions
Trans sodium crocetinate (TSC), 0.9% normal saline
Drug
Lead sponsor
Diffusion Pharmaceuticals Inc
Industry
Eligibility
40 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
7
States / cities
Birmingham, Alabama • Santa Rosa, California • Stanford, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2011 · Synced Oct 14, 2026, 11:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Magnetic Resonance Imaging to Identify Characteristics of Plaque Build-Up in People With Peripheral Arterial Disease

NCT00520312
View directory record Official record
Conditions
Peripheral Vascular Diseases
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
21 Years and older
Enrollment
519 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 9, 2014 · Synced Oct 14, 2026, 11:38 AM EDT
Terminated Phase 3 Interventional

Efficacy/Safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease

NCT00059644
View directory record Official record
Conditions
Peripheral Vascular Disease
Interventions
Ecraprost in lipid emulsion
Drug
Lead sponsor
Tanabe Pharma Corporation
Industry
Eligibility
40 Years and older
Enrollment
560 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
20
States / cities
Phoenix, Arizona • Tucson, Arizona • Glendale, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 14, 2026, 11:38 AM EDT
Completed Not applicable Interventional

Comorbidity Screening and Referral by Prosthetists

NCT05410548
View directory record Official record
Conditions
Limb Ischemia, Low Back Pain, Depression, Neuropathy;Peripheral, Amputation
Interventions
Standard-of-Care, Clinical Screening
Other
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Dec 31, 2025 · Synced Oct 14, 2026, 11:38 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

The Pharmacokinetics and Pharmacodynamics Study of Evategrel CG-0255 Besylate）and Plavix® in Healthy Participants

NCT07619885
View directory record Official record
Conditions
Acute Coronary Syndromes (ACS), Recent Myocardial Infarction, Recent Stroke, Peripheral Arterial Disease
Interventions
CG-0255 Besylate for Injection, CG-0255 Besylate Capsule, Clopidogrel
Drug
Lead sponsor
Shanghai CureGene Pharmaceutical Co., Ltd.
Industry
Eligibility
18 Years to 55 Years
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 14, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

Tack Optimized Balloon Angioplasty Study of the Tack Endovascular System™ in Femoropoliteal Arteries

NCT02522884
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Tack Endovascular System
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years and older
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
36
States / cities
Yuma, Arizona • Little Rock, Arkansas • Beverly Hills, California + 31 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Oct 14, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

AngioSafe Peripheral CTO Crossing System Study (RESTOR-1 Study)

NCT04663867
View directory record Official record
Conditions
Peripheral Artery Occlusion, Peripheral Arterial Disease
Interventions
AngioSafe Peripheral CTO Crossing System
Device
Lead sponsor
AngioSafe, Inc.
Industry
Eligibility
22 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
18
States / cities
Chandler, Arizona • St. Helena, California • Darien, Connecticut + 15 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 14, 2026, 11:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparing BlueDop Vascular Expert to Ankle-Brachial Index in the Identification of Peripheral Vascular Disease

NCT06436001
View directory record Official record
Conditions
Peripheral Arterial Disease, Diabetes Mellitus
Interventions
Not listed
Lead sponsor
Dakota Vascular
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Jun 3, 2024 · Synced Oct 14, 2026, 11:38 AM EDT
Completed No phase listed Observational

FLEX Arteriovenous Access Registry

NCT04070365
View directory record Official record
Conditions
Peripheral Artery Disease, Arteriovenous Fistula Stenosis, Arteriovenous Graft Stenosis
Interventions
FLEX Vessel Prep System followed by angioplasty
Device
Lead sponsor
VentureMed Group Inc.
Industry
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
10
States / cities
Birmingham, Alabama • Dothan, Alabama • Tuscaloosa, Alabama + 7 more
Source: ClinicalTrials.gov public record
Updated May 31, 2022 · Synced Oct 14, 2026, 11:38 AM EDT
Completed Phase 1 Interventional

Natural Vascular Scaffold (NVS) Therapy

NCT03148808
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Diseases, Catheterization, Peripheral
Interventions
NVS Therapy
Combination Product
Lead sponsor
Alucent Biomedical
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
3
States / cities
Columbus, Ohio • Wynnewood, Pennsylvania • Kingsport, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 14, 2018 · Synced Oct 14, 2026, 11:38 AM EDT
Completed Not applicable Interventional

Detour2 Continued Access Study

NCT04625660
View directory record Official record
Conditions
Peripheral Artery Diseases
Interventions
PQ Bypass System
Device
Lead sponsor
Endologix
Industry
Eligibility
18 Years to 90 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
Old Saybrook, Connecticut • Elk Grove Village, Illinois • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 14, 2026, 11:38 AM EDT
Completed No phase listed Observational

A Long Term Follow-up Study of AMG0001 in Subjects With Critical Limb Ischemia

NCT02974179
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
Subjects from Study AG-CLI-0206 who received AMG0001
Biological
Lead sponsor
AnGes USA, Inc.
Industry
Eligibility
40 Years to 90 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 12, 2020 · Synced Oct 14, 2026, 11:38 AM EDT
Completed Not applicable Interventional

FORMAT Clinical Study

NCT01804088
View directory record Official record
Conditions
Symptomatic Vascular Disease of the Iliac Arteries
Interventions
Formula™ 535 Iliac Balloon-Expandable Stent
Device
Lead sponsor
Cook Group Incorporated
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
12
States / cities
La Jolla, California • Bradenton, Florida • Jacksonville, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2018 · Synced Oct 14, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

Safety and Efficacy of the SurVeil™ Drug-Coated Balloon

NCT03241459
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Disease, Artery Disease, Peripheral, Femoropopliteal Artery Occlusion
Interventions
Surmodics SurVeil DCB, Medtronic IN.PACT Admiral DCB
Device
Lead sponsor
SurModics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
446 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
50
States / cities
Birmingham, Alabama • Foley, Alabama • Gilbert, Arizona + 45 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 14, 2026, 11:38 AM EDT
Completed Phase 3 Interventional

Evaluating Two Exercise Training Programs to Reduce Leg Pain in People With Peripheral Arterial Disease (The EXERT Study)

NCT00895635
View directory record Official record
Conditions
Intermittent Claudication, Peripheral Vascular Diseases
Interventions
Treadmill Exercise Training, Arm Ergometry Exercise Training, Usual Care
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 90 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 1, 2019 · Synced Oct 14, 2026, 11:38 AM EDT
Recruiting Phase 3 Interventional

Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease

NCT07318610
View directory record Official record
Conditions
Peripheral Artery Disease (PAD)
Interventions
REGN7508, REGN9933, Placebo, Rivaroxaban
Drug
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
7,050 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
20
States / cities
Alexander City, Alabama • Avondale, Arizona • Little Rock, Arkansas + 17 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 14, 2026, 11:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Understanding the Genetic Basis of Atherosclerosis and Peripheral Arterial Disease

NCT00380185
View directory record Official record
Conditions
Peripheral Vascular Diseases
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
40 Years and older
Enrollment
1,789 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2004
U.S. locations
2
States / cities
Stanford, California • New York, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2015 · Synced Oct 14, 2026, 11:38 AM EDT
Recruiting Phase 3 Interventional

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

NCT07223593
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Orforglipron, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
1,205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
36
States / cities
Birmingham, Alabama • Gilbert, Arizona • Surprise, Arizona + 31 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 14, 2026, 11:38 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pharmacokinetic Study of Once Daily PMR Compared to Twice Daily Cilostazol IR Tablets in Healthy Volunteers

NCT03480321
View directory record Official record
Conditions
Intermittent Claudication
Interventions
Cilostazol 100 mg, PMR 150 mg, PMR 200 mg
Drug
Lead sponsor
Genovate Biotechnology Co., Ltd.,
Industry
Eligibility
18 Years to 45 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 10, 2018 · Synced Oct 14, 2026, 11:38 AM EDT
Completed Phase 4 Interventional Results available

A Randomized Clinical Trial Evaluating Negative Pressure Therapy to Decrease Vascular Groin Incision Complications

NCT02581904
View directory record Official record
Conditions
Wound Infection, Peripheral Arterial Disease, Aneurysm, Surgical Wound Dehiscence
Interventions
Prevena Care, Dry gauze dressing care
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 100 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 14, 2026, 11:38 AM EDT
Completed Phase 1 Interventional

Safety/Feasibility of Vonapanitase Following Angioplasty for Patients With Peripheral Artery Disease (PAD) Below the Knee (BTK)

NCT02956993
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
vonapanitase, Placebo
Drug
Lead sponsor
Proteon Therapeutics
Industry
Eligibility
18 Years to 100 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
9
States / cities
Long Beach, California • Denver, Colorado • Gainesville, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Oct 14, 2026, 11:38 AM EDT
Completed Not applicable Interventional Results available

Complete Lesion Assessment With ffR and IVUS TechnologY

NCT01941030
View directory record Official record
Conditions
Peripheral Artery Disease, Critical Limb Ischemia
Interventions
Orbital Atherectomy System, Balloon Angioplasty
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
8
States / cities
Little Rock, Arkansas • Atlanta, Georgia • Davenport, Iowa + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2023 · Synced Oct 14, 2026, 11:38 AM EDT
Recruiting Not applicable Interventional

Leg Heat Therapy in Peripheral Artery Disease

NCT05465070
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Leg heat therapy, Sham Control
Device
Lead sponsor
Indiana University
Other
Eligibility
50 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 14, 2026, 11:38 AM EDT