- Conditions
- Arthroplasty Shoulder, Periprosthetic Joint Infection
- Interventions
- Chlorhexidine Gluconate
- Drug
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years to 89 Years · Male only
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Seattle, Washington
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Showing 1–24
of 28
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Prosthetic-joint Infection
- Interventions
- VT-X7 Treatment System, Two-stage exchange arthroplasty, SOC Antibiotics, Experimental Antibiotics
- Combination Product · Procedure · Drug
- Lead sponsor
- Osteal Therapeutics, Inc.
- Industry
- Eligibility
- 22 Years to 84 Years
- Enrollment
- 76 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 19
- States / cities
- Phoenix, Arizona • Los Angeles, California • Sarasota, Florida + 15 more
- Conditions
- Prosthetic Joint Infection
- Interventions
- VT-X7 Treatment System with Tobramycin Sulfate, Standard of Care, Two-stage exchange arthroplasty, VT-X7 Treatment System with Vancomycin Hydrochloride
- Combination Product · Drug · Procedure
- Lead sponsor
- Osteal Therapeutics, Inc.
- Industry
- Eligibility
- 22 Years to 84 Years
- Enrollment
- 76 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 17
- States / cities
- Phoenix, Arizona • Torrance, California • Washington D.C., District of Columbia + 13 more
- Conditions
- Infections Joint Prosthetic, Overweight or Obesity, MSSA Colonization, MRSA, Chronic Kidney Diseases, Diabetes, Autoimmune Diseases, Inflammatory Disease, Tobacco Use
- Interventions
- Cephalexin, Doxycycline, Cefadroxil
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 4,618 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2028
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa • Rochester, Minnesota
- Conditions
- Prosthetic-joint Infection
- Interventions
- Surgiphor Irrigation Solution, Sterile saline
- Device
- Lead sponsor
- Center for Innovation and Research Organization
- Network
- Eligibility
- 18 Years and older
- Enrollment
- 868 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 4
- States / cities
- Phoenix, Arizona • Baltimore, Maryland • Columbia, Missouri + 1 more
- Conditions
- Joint Infection
- Interventions
- PLG0206
- Drug
- Lead sponsor
- Peptilogics
- Industry
- Eligibility
- 18 Years to 79 Years
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 12
- States / cities
- Palo Alto, California • Sarasota, Florida • Baltimore, Maryland + 8 more
- Conditions
- Prosthetic-joint Infection, Knee Infection, Arthroplasty Complications, Joint Infection, Arthroplasty, Replacement, Knee
- Interventions
- All-cement articulating spacer, Durable, real-component articulating spacer, Rigid Spacer
- Device
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 153 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Aseptic Loosening of Prosthetic Joint, Instability of Prosthetic Joint, Reimplantation for Periprosthetic Joint Infection, Femoral Revision Indicated, Tibial Component Revision
- Interventions
- Constrained Condylar bearing, posterior stabilized bearing
- Device
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2038
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Prosthetic Joint Infection
- Interventions
- No intervention: sample collection study
- Other
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Periprosthetic Joint Infection
- Interventions
- REMEDY Spectrum IM Spacer Nail
- Combination Product
- Lead sponsor
- OsteoRemedies, LLC
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 3
- States / cities
- Lansing, Michigan • Charlotte, North Carolina • Durham, North Carolina
- Conditions
- PJI
- Interventions
- Synovasure® Comprehensive Infection Panel
- Diagnostic Test
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 810 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Periprosthetic Joint Infection
- Interventions
- Single Debridement, Antibiotics and Implant Retention, Planned Double Debridement, Antibiotics and Implant Retention
- Procedure
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 490 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2032
- U.S. locations
- 2
- States / cities
- Jacksonville, Florida • Rochester, Minnesota
- Conditions
- Periprosthetic Joint Infection
- Interventions
- Synovasure PJI Lateral Flow test and Synovasure PJI ELISA Test
- Device
- Lead sponsor
- CD Diagnostics
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 3,000 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Prosthetic-joint Infection
- Interventions
- PLG0206, Placebo
- Drug
- Lead sponsor
- Peptilogics
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 13
- States / cities
- Sarasota, Florida • Tamarac, Florida • Baltimore, Maryland + 10 more
- Conditions
- Periprosthetic Joint Infection, Antibiotic Suppression
- Interventions
- 6 months of SAT, 12 months of SAT, Indefinite SAT
- Drug
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Total Joint Arthroplasty, Periprosthetic Joint Infections
- Interventions
- Blood Draw or Saliva/Cheek Cell Sample:
- Genetic
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 150 participants
- Timeline
- 2018 – 2028
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Prosthetic-joint Infection
- Interventions
- Semi-quantitative electrochemical leukocyte esterse test strip, Roche Chemstrip
- Diagnostic Test
- Lead sponsor
- Center for Innovation and Research Organization
- Network
- Eligibility
- 18 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 8
- States / cities
- Denver, Colorado • Weston, Florida • Louisville, Kentucky + 5 more
- Conditions
- Periprosthetic Joint Infection
- Interventions
- Sterile Water, 3.5% Betadine, 0.05% Chlorhexidine Gluconate
- Other
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Prosthetic-joint Infection
- Interventions
- VT-X7 Treatment System
- Combination Product
- Lead sponsor
- Osteal Therapeutics, Inc.
- Industry
- Eligibility
- 22 Years to 84 Years
- U.S. locations
- 14
- States / cities
- Phoenix, Arizona • Los Angeles, California • Grand Junction, Colorado + 11 more
- Conditions
- Surgical Site Infection
- Interventions
- One-stage exchange joint replacement surgery, Two-stage exchange joint replacement surgery
- Procedure
- Lead sponsor
- OrthoCarolina Research Institute, Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 343 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2026
- U.S. locations
- 5
- States / cities
- Chicago, Illinois • New York, New York • Charlotte, North Carolina + 2 more
- Conditions
- Prosthetic Joint Infection
- Interventions
- leukocyte esterase electrochemical assay
- Diagnostic Test
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 230 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Periprosthetic Joint Infections
- Interventions
- EP Granules with Tobramycin, empty voids
- Device
- Lead sponsor
- Elute, Inc.
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 204 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2029
- U.S. locations
- 16
- States / cities
- Los Angeles, California • Washington D.C., District of Columbia • Skokie, Illinois + 12 more
- Conditions
- Periprosthetic Joint Infection (PJI)
- Interventions
- Ultrasound-triggered microbubble destruction with antibiotics
- Drug
- Lead sponsor
- Thomas Jefferson University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 2
- States / cities
- Pittsburgh, Pennsylvania • Dallas, Texas
- Conditions
- Infection, Bacterial
- Interventions
- Using surgical diathermy to make skin incision, Using scalpel blade to make skin incision
- Procedure
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Columbia, Missouri