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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Results available

Efficacy of an Internet-based Intervention for Dental Anxiety

NCT03680755
View directory record Official record
Conditions
Dental Anxiety
Interventions
Internet-based intervention for dental anxiety
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 75 Years
Enrollment
503 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 16, 2025 · Synced Jun 10, 2026, 2:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Generalized Anxiety Disorder and Social Anxiety Disorder: Their Impact on the Processing of Information and Learning

NCT00062517
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
497 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 5, 2017 · Synced Jun 10, 2026, 2:24 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Treatment of Pediatric Anxiety Disorders by Predicting Treatment Response Through Biocellular Markers and Sleep

NCT02189213
View directory record Official record
Conditions
Generalized Anxiety Disorder, Separation Anxiety Disorder, Social Phobia
Interventions
Sertraline
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
8 Years to 25 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 10, 2021 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Phase 1Phase 2 Interventional

Treatment for Specific Phobias in Children

NCT00051220
View directory record Official record
Conditions
Phobic Disorders, Anxiety Disorders
Interventions
One-Session Treatment for Specific Phobias
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
7 Years to 16 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 6, 2013 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Phase 4 Interventional Results available

Improving Treatment Outcomes in Pharmacotherapy of Generalized Social Anxiety Disorder

NCT00282828
View directory record Official record
Conditions
Social Phobia
Interventions
Sertraline, Venlafaxine, Placebo, Clonazepam
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
397 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
2
States / cities
La Jolla, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2013 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Effect of Oxytocin Nasal Sprays on Social Behavior in Social Anxiety Disorder

NCT01856530
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Stefan G. Hofmann
Other
Eligibility
18 Years and older · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 12, 2018 · Synced Jun 10, 2026, 2:24 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Impact of Medical Play in the Dental Clinic Setting on the Cooperation of Neurotypical Patients

NCT05571423
View directory record Official record
Conditions
Dental Phobia, Dental Anxiety, Oral Aversion
Interventions
Medical Play, Routine Play
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
5 Years to 10 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Social Anxiety MDMA-Assisted Therapy Investigation

NCT05138068
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
MDMA, Psychotherapy
Drug · Behavioral
Lead sponsor
Jason B Luoma
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Results available

Variations of Cognitive Behavior Therapy for Social Anxiety Disorder

NCT00948974
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Cognitive Therapy, Acceptance and Commitment Therapy
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 4, 2018 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional

Youth Mayo Clinic Anxiety Coach Randomized Controlled Trial

NCT02205203
View directory record Official record
Conditions
Anxiety
Interventions
Mayo Clinic Anxiety Coach, Treatment as Usual
Device · Other
Lead sponsor
Stephen Whiteside
Other
Eligibility
7 Years to 17 Years
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 28, 2021 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety

NCT01919970
View directory record Official record
Conditions
Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder, Obsessive-compulsive Disorder, Specific Phobia
Interventions
Cognitive Behavioral Therapy, Treatment as usual
Other
Lead sponsor
University of South Florida
Other
Eligibility
6 Years to 12 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Jun 13, 2019 · Synced Jun 10, 2026, 2:24 PM EDT
Terminated Not applicable Interventional Results available

Bringing Exposure Therapy to Real-Life Context With Augmented Reality

NCT03649347
View directory record Official record
Conditions
Phobias Snakes, Phobias Spiders
Interventions
Augmented reality exposure therapy
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Effects of Low-Level Laser Stimulation With and Without Fear Extinction Training

NCT02926352
View directory record Official record
Conditions
Phobias, Claustrophobia, Social Phobia
Interventions
Extinction Training, Low-Level Laser Therapy, Sham Low-Level Laser Therapy
Behavioral · Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 27, 2022 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional

Examining Long-Term Effects and Neural Mediators of Behavioral Treatments for Social Anxiety Disorder

NCT00872820
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Acceptance- and commitment-based behavioral therapy, Cognitive behavioral therapy
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 45 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2014 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional

Internet-Based, Parent-Led Cognitive-Behavioral Therapy for Anxiety in Youth With ASD

NCT05284435
View directory record Official record
Conditions
Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorder, Obsessive-Compulsive Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder, Specific Phobia
Interventions
Cognitive Behavioral Therapy-Email (iCBT-E), Cognitive Behavioral Therapy-Email and Videoconferencing (iCBT-EV)
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
7 Years to 15 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pediatric Anxiety Intervention With an Entertaining Video Game: Feasibility Study

NCT02713425
View directory record Official record
Conditions
Anxiety
Interventions
Entertaining Video Game
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
7 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 3, 2019 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessing Mechanisms of Anxiety Reduction in Animal-assisted Interventions

NCT03249116
View directory record Official record
Conditions
Social Anxiety Disorder, Social Anxiety, Social Anxiety Disorder of Childhood
Interventions
animal-assisted intervention, active control
Other
Lead sponsor
Tufts University
Other
Eligibility
13 Years to 17 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
North Grafton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2020 · Synced Jun 10, 2026, 2:24 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Individual Factors of CBT Underlying Success

NCT06678295
View directory record Official record
Conditions
Social Anxiety Disorder, Body Dysmorphic Disorder
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 45 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Phase 2Phase 3 Interventional

Quetiapine in Social Anxiety Disorder

NCT00215254
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
quetiapine
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 18, 2006 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional Results available

Reduction of Claustrophobia and Patient Motion After Training of MRI Personnel in Comfort TalkTM

NCT01563198
View directory record Official record
Conditions
Claustrophobia, Complication of Diagnostic Procedure
Interventions
Comfort Talk®
Behavioral
Lead sponsor
Hypnalgesics, LLC
Industry
Eligibility
Not listed
Enrollment
97,712 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
4
States / cities
Boston, Massachusetts • Brookline, Massachusetts • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional

Augmentation of Exposure Therapy for High Levels of Social Anxiety Using Post-exposure Naps

NCT02325128
View directory record Official record
Conditions
Social Anxiety Disorder, Sleep Laboratory
Interventions
Sleep-enhancement of extinction memory
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 40 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Computerized Cognitive Behavioral Therapy for Childhood Anxiety in Community Health Centers

NCT01416805
View directory record Official record
Conditions
Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder
Interventions
Computerized Cognitive Behavioral Therapy, Treatment as usual
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
7 Years to 13 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
4
States / cities
Clearwater, Florida • Fort Lauderdale, Florida • Pensacola, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2019 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional

The Effects of Safety Seeking Behaviors During Exposure Therapy for Adults With Spider Phobia

NCT03233113
View directory record Official record
Conditions
Specific Phobia
Interventions
Exposure therapy
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 15, 2018 · Synced Jun 10, 2026, 2:24 PM EDT
Completed Not applicable Interventional

Virtual Reality Exposure Therapy for the Treatment of Social Phobia

NCT02379949
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
Virtual Reality Exposure Therapy, Exposure Group Therapy
Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 4, 2015 · Synced Jun 10, 2026, 2:24 PM EDT