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ClinicalTrials.gov public records Last synced Oct 20, 2026, 6:29 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 169 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Positive-Pressure Respiration, Intrinsic Clear all

Conditions: Obstructive Sleep Apnea
Interventions: Not listed
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 22 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Sleep Apnea
Interventions: Health coaching; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 131 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Sleep Apnea, Obstructive
Interventions: nasopharyngeal airway obstructive sleep apnea (NPA-OSA) device; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Ann Arbor, Michigan

Conditions: Sleep Apnea, Obstructive
Interventions: Paced Breathing; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 21 Years to 70 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obstructive Sleep Apnea
Interventions: BONGO NASAL EPAP; Device
Lead sponsor: InnoMed Healthscience Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Positive-Pressure Respiration, Communication
Interventions: F2S Communicator, Non-functioning Communicator; Device · Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 3
States / cities: Atlanta, Georgia

Conditions: Obstructive Sleep Apnea, Atrial Fibrillation
Interventions: Cardiac Ablation for Atrial Fibrillation; Procedure
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Obstructive Sleep Apnea
Interventions: Eszopiclone 2 mg, Placebo; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 21 Years to 65 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Obstructive Sleep Apnea
Interventions: Telemedicine Education, IVR; Behavioral
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 1,873 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Fontana, California

Conditions: Gastroesophageal Reflux, Sleep Apnea
Interventions: Continuous positive airway pressure ventilation; Procedure
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Sleep Apnea, Obstructive, Continuous Positive Airway Pressure
Interventions: MET, ED; Behavioral
Lead sponsor: National Jewish Health; Other
Eligibility: 30 Years to 80 Years
Enrollment: 306 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2015
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Sleep Apnea
Interventions: Analysis with AED and manual PSG scoring; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 21 Years to 75 Years
Enrollment: 115 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Sleep Apnea, Obstructive, Brain Injuries, Traumatic
Interventions: MI and CBT 4-session manualized intervention; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Down Syndrome, Obstructive Sleep Apnea Syndrome
Interventions: Continuous positive airway pressure, Sham or placebo continuous positive airway pressure; Device
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: 8 Years to 20 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Asthma
Interventions: CPAP-Continuous Positive Airway Pressure, SHAM; Device
Lead sponsor: Indiana University; Other
Eligibility: 8 Years to 60 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2012
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Sleep Apnea, Obstructive Sleep Apnea
Interventions: Eszopiclone, Placebo; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: North Haven, Connecticut

Conditions: Obstructive Sleep Apnea
Interventions: IHL-42X Low Dose, IHL-42X High Dose, Placebo, IHL-42X (Optimal Dose), Dronabinol, Acetazolamide; Drug
Lead sponsor: Incannex Healthcare Ltd; Industry
Eligibility: 18 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 20
States / cities: Chula Vista, California • Long Beach, California • Upland, California + 16 more

Conditions: Sleep Apnea, Obstructive, Obesity Hypoventilation Syndrome (OHS), Sleep Apnea Syndromes
Interventions: Not listed
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Sleep Apnea
Interventions: PAP; Device
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 21 Years to 80 Years
Enrollment: 209 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sleep Apnea
Interventions: SAM Clinic Intervention; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Sleep Apnea, Sleep Disturbance
Interventions: Couples-based treatment- Patient, Couples-based treatment- Partner, Information control- Patient, Information control- Partner; Behavioral · Other
Lead sponsor: University of Utah; Other
Eligibility: 35 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: Tuscon, Arizona • Salt Lake City, Utah

Conditions: Obstructive Sleep Apnea, Obesity
Interventions: Laparoscopic Gastric Banding, Continuous Positive Airway Pressure; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 65 Years
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Obstructive Sleep Apnea
Interventions: Immediate Intervention, Waitlist control; Behavioral
Lead sponsor: VA Greater Los Angeles Healthcare System; Federal
Eligibility: 21 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: North Hills, California

Conditions: Obstructive Sleep Apnea (OSA)
Interventions: Weekly phone calls, Frequently asked questions, Usual care; Behavioral
Lead sponsor: CAMC Health System; Other
Eligibility: 18 Years and older
Enrollment: 128 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Charleston, West Virginia

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Head to Head Comparison of Upper Airway Stimulation and Continuous Positive Airway Pressure; a Pilot Study.

Health Coaching for Positive Airway Pressure Adherence

NPA-OSA Device Tolerability, Usability and Acclimation Clinical Study in Adult Obstructive Sleep Apnea (OSA) Patients

Evaluation of an Algorithm to Detect Sleep and Wake in Continuous Positive Airway Pressure (CPAP)

Clinical Study for the BONGO NASAL Expiratory Positive Airway Pressure (EPAP) Device in the Treatment of Obstructive Sleep Apnea (OSA)

Determining the Benefits of Improving Communication in BPAP/CPAP Users

Effects of PAP on Afib Recurrence Risk After Catheter Ablation in OSA Patients

Endotype-Targeted Therapy to Rescue OSA Patients Struggling With CPAP Adherence (TOP-CPAP)

Impact of Automated Education and Follow-up Mechanisms on Patient Engagement

Evaluation of Gastroesophageal Reflux in Patients on Continuous Positive Airway Pressure Ventilation for Obstructive Sleep Apnea

Evaluating Behavioral Treatments to Improve Adherence to Continuous Positive Airway Pressure (CPAP) Therapy in People With Obstructive Sleep Apnea (The BREATHE Study)

Comparison of Breathing Event Detection by a Continuous Positive Airway Pressure Device to Clinical Polysomnography

Feasibility of Improving Sleep Apnea Treatment Adherence After Brain Injury

Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome

Assessment Of The Effects Of Short and Long Term Use Of CPAP

Continuous Positive Airway Pressure, Arousability and Links to Mechanisms in Obstructive Sleep Apnea

RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA

Evaluation of An Optical Measurement Algorithm Combined With Patient and Provider Input to Reduce Mask Exchanges During Initial Positive Airway Pressure Therapy

Phenotyping Mechanistic Pathways for Adverse Health Outcomes in Sleep Apnea

SAMPAP Trial -Impact of a Novel Sleep Apnea Management Group Intervention on Positive Airway Pressure Adherence

Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples With Implications for Alzheimer's Disease Risk

Apnea, Bariatric Surgery Versus Continuous Positive Airway Pressure (CPAP) Trial

Chronic Care Management With Wearable Devices in Patients Prescribed Positive Airway Pressure Therapy (mPAP) Trial

Weekly Phone Calls Versus Brief Patient Education to Improve CPAP (Continuous Positive Airway Pressure) Compliance