- Conditions
- Anterior Cruciate Ligament Injuries, Post-Traumatic Osteoarthritis of Knee, Bone Marrow Aspirate Concentrate, ACL Injury
- Interventions
- Concentrated Bone Marrow Aspirate Injection, Sham Incision, Revision Anterior Cruciate Ligament Reconstruction
- Biological · Procedure
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 2
- States / cities
- Atlanta, Georgia • New York, New York
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Pain, Postoperative
- Interventions
- Bupivacaine HCl 0.5% Injectable Solution, Dexamethasone, Infiltration between Popliteal Artery and Capsule of the knee (iPACK), Percocet 5Mg-325Mg Tablet
- Drug · Procedure
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 154 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- ACL Tear
- Interventions
- Safe Return to Play Following ACL Reconstruction Checklist
- Diagnostic Test
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 15 Years to 35 Years
- Enrollment
- 222 participants
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Pain, Postoperative, Anterior Cruciate Ligament Injuries, Analgesics, Opioid
- Interventions
- IPACK, PLACEBO
- Drug
- Lead sponsor
- Loyola University
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 78 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Maywood, Illinois
- Conditions
- ACL Injury
- Interventions
- Exercise Blood Flow Restriction training, SHAM Exercise Blood Flow Restriction training
- Behavioral
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 13 Years to 40 Years
- Enrollment
- 29 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Scottsdale, Arizona
- Conditions
- ACL Injury, Meniscus Tear, Post-traumatic Osteoarthritis
- Interventions
- Montelukast, Placebo
- Drug
- Lead sponsor
- Austin V Stone
- Other
- Eligibility
- 25 Years to 50 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2027
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Anterior Cruciate Ligament Tear, Knee Meniscus Tear
- Interventions
- Femoral Nerve Block, Adductor Canal Nerve Block, preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine, Preoperative Adductor canal block with 0.75%% ropivacaine 13.3ml.
- Procedure · Drug
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 132 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Anterior Cruciate Ligament Reconstruction
- Interventions
- iovera°
- Device
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 18 Years to 49 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- ACL Repair
- Interventions
- Cryoneurolysis
- Procedure
- Lead sponsor
- Virtua Health, Inc.
- Other
- Eligibility
- 14 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 2
- States / cities
- Burlington, New Jersey • Cherry Hill, New Jersey
- Conditions
- Anterior Cruciate Ligament Injuries
- Interventions
- Operant Conditioning, Control
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 14 Years to 45 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Anterior Cruciate Ligament Injuries
- Interventions
- Opiate Sparing, Opiate Based
- Drug
- Lead sponsor
- Campbell Clinic
- Other
- Eligibility
- 14 Years to 85 Years
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 3
- States / cities
- Skokie, Illinois • Cincinnati, Ohio • Memphis, Tennessee
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Sports Injuries in Children, Analgesia, Pain, Postoperative
- Interventions
- Ropivacaine 0.2% Injectable Solution
- Drug
- Lead sponsor
- Texas Scottish Rite Hospital for Children
- Other
- Eligibility
- 13 Years to 21 Years
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Frisco, Texas
- Conditions
- ACL Injury, Post Operative Pain
- Interventions
- Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + iPACK Block
- Drug
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 12 Years and older
- Enrollment
- 82 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- ACL, ACL Injury
- Interventions
- Split-belt Training, Tied-Belt Training
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 14 Years to 45 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- ACL Injury
- Interventions
- Bupivacaine
- Drug
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Plainview, New York
- Conditions
- ACL Reconstruction, ACL Surgery, ACL Injury, Electrotherapy, Muscle Atrophy or Weakness
- Interventions
- Zynex NexWave Electrotherapy Device
- Device
- Lead sponsor
- University of Kansas Medical Center
- Other
- Eligibility
- 15 Years to 50 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Kansas City, Kansas
- Conditions
- ACL Reconstruction
- Interventions
- Methyl Prednisolone (MP), Standard Post-Operative Pain Control, Surgeon's Standard ACL Postoperative Regimen
- Drug · Combination Product
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 14 Years to 65 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2031
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- ACL Reconstruction
- Interventions
- Whey protein isolate, Protein + BAA, Placebo
- Dietary Supplement
- Lead sponsor
- The Methodist Hospital Research Institute
- Other
- Eligibility
- 16 Years to 40 Years
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Scarring
- Interventions
- Standard Post Operative Skin Care, Medipore Tape
- Other
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 15 Years to 95 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis, Knee
- Interventions
- No Intervention - Observational study with MRI
- Other
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 22 Years to 45 Years
- Enrollment
- 219 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2030
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Anterior Cruciate Ligament Reconstruction
- Interventions
- Plyometric Exercise
- Behavioral
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 15 Years to 30 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Anterior Cruciate Ligament Injuries
- Interventions
- Graded Exposure and Mindfulness Meditation, Waitlist Control
- Behavioral
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 14 Years to 35 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Post-operative Pain, Quadriceps Muscle Strength
- Interventions
- Adductor Canal Block, Femoral Nerve Block, Ultrasound, Stimuplex A needle, local anaesthetic injection, Steroid Drug
- Procedure · Device · Drug
- Lead sponsor
- Akron Children's Hospital
- Other
- Eligibility
- 8 Years to 18 Years
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Akron, Ohio
- Conditions
- Bone Graft; Complications, ACL Injuries
- Interventions
- autologous bone grafts, Demineralized bone matrix (DBM)
- Procedure · Other
- Lead sponsor
- University of Arizona
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 3
- States / cities
- Phoenix, Arizona • Scottsdale, Arizona