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Conditions: Hypertension
Interventions: Pulsewave oscillometric wrist cuff blood pressure monitor; Device
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2016
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Preeclampsia, Hypertensive Disorder of Pregnancy, Toxemia, Pregnancy Complications, Hypertension, Pregnancy-Induced, Hypertension, Obesity, Overweight, Nutrition Disorders, Vascular Diseases, Cardiovascular Diseases, Pre-Eclampsia, Eclampsia, Gestational Hypertension
Interventions: Heart Health Doula Intervention Program, Usual Care; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older · Female only
Enrollment: 454 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Hypertension, Pregnancy-Induced
Interventions: Acetaminophen, Ibuprofen; Drug
Lead sponsor: MemorialCare Health System; Other
Eligibility: 18 Years and older · Female only
Enrollment: 202 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Long Beach, California

Conditions: Preeclampsia With Severe Features
Interventions: Cheetah® non-invasive cardiac monitoring system, Standard of care; Device · Other
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Preeclampsia Severe or Mild, Cardiac Complication
Interventions: Echocardiogram, Blood draw; Diagnostic Test
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 27 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Hypertensive Disorder of Pregnancy
Interventions: Remote Patient Monitoring; Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 213 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Pregnancy-Associated Hypertension, Gestational Hypertension, Preeclampsia, Eclampsia, HELLP Syndrome, Postpartum Hypertension, Stage 2 Hypertension
Interventions: Alabama Womb to Heart Solution (AW2H) Community Health Worker (CHW) Program, Usual postpartum care with self-measured blood pressure education and home blood pressure monitor; Behavioral · Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 16 Years to 56 Years · Female only
Enrollment: 174 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Postpartum Preeclampsia, Hypertension in Pregnancy
Interventions: Labetalol Oral Tablet, NIFEdipine ER; Drug
Lead sponsor: Nebraska Methodist Health System; Other
Eligibility: 19 Years and older · Female only
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia, Hypertension, Pregnancy-Induced, Hypertension
Interventions: Furosemide, Placebo; Drug · Other
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Cardiovascular Diseases, Diabetes, Gestational Diabetes, Preeclampsia, Gestational Hypertension, Small for Gestational Age at Delivery, Preterm Birth, Overweight and Obesity
Interventions: Fit After Baby, Text4Baby Control Group; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Preeclampsia, Microvascular Function
Interventions: Acetylcholine, Endothelin-1; Drug
Lead sponsor: Anna Stanhewicz, PhD; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Hypertension, Pregnancy-Induced, Postpartum Preeclampsia, Hypertension; Maternal
Interventions: Blood Pressure Control Targets, Hypertension Management; Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 343 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Preeclampsia, Preeclampsia Postpartum
Interventions: Eplerenone; Drug
Lead sponsor: Anna Stanhewicz, PhD; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Postpartum Hemorrhage, Postpartum Preeclampsia, Postpartum Sepsis, Postpartum Depression, Patient Empowerment, Patient Education, Postpartum Care
Interventions: Video Education; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Hypertension, Pregnancy-Induced, Hypertension, Postpartum Preeclampsia, Postpartum Complication, Postpartum Pre-Eclampsia, Cardiovascular Diseases, Cardiovascular Morbidity, Morbidity;Perinatal
Interventions: BP Watch; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Hypertension, Pregnancy-Induced
Interventions: furosemide, labetalol; Drug
Lead sponsor: Wright State University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Dayton, Ohio

Conditions: Pregnant Women With Singleton Pregnancies
Interventions: Food Kit; Other
Lead sponsor: Texas A&M University; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 800 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 3
States / cities: College Station, Texas • Dallas, Texas • Mansfield, Texas

Conditions: Pre-Eclampsia, Gestational Hypertension, Superimposed Pre-Eclampsia, Hypertension, Pregnancy-Induced, Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia
Interventions: Hydrochlorothiazide 50mg Tablet, Placebo Tablet; Drug
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 453 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2025
U.S. locations: 2
States / cities: Austin, Texas • Galveston, Texas

Conditions: Pre-eclampsia, Pregnancy, Post Partum
Interventions: Not listed
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Hypertension, Preeclampsia
Interventions: Norethindrone 0.35 MG, Drospirenone; Drug
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Hypertensive Disorder of Pregnancy, Pre-Eclampsia, Hypertension, Eclampsia, Gestational Hypertension, Cardiovascular Diseases, Toxemia, Pregnancy Complications, Vascular Diseases, Hypertension, Pregnancy Induced, Hypertension;Pre-Eclamptic
Interventions: Usual care, Tight blood pressure control; Drug
Lead sponsor: Alisse Hauspurg; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Hypertension in Pregnancy, Postpartum Preeclampsia
Interventions: Education provided via a video format; Other
Lead sponsor: Medstar Health Research Institute; Other
Eligibility: 18 Years and older · Female only
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Preeclampsia, Preeclampsia Severe, Gestational Hypertension, Hypertensive Disorder of Pregnancy, Superimposed Pre-Eclampsia
Interventions: Nudge; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years and older · Female only
Enrollment: 224 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Preeclampsia
Interventions: Compound 21, Angiotensin II; Drug
Lead sponsor: Anna Stanhewicz, PhD; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Iowa City, Iowa

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Validation of Pulsewave Blood Pressure Monitor in Hypertensive and Normotensive Pregnant and Postpartum Women

Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial

Hypertension In Postpartum Preeclampsia Study

Use of Cheetah® Cardiac Monitoring System to Guide Discontinuation of Magnesium Sulfate in Women With Severe Preeclampsia

Persistent Postpartum Cardiovascular Dysfunction in Patients With Preeclampsia

Remote BP Monitoring in the PP Period

Community Health Worker Support to Lower Blood Pressure After a Pregnancy With High Blood Pressure

Labetalol or Nifedipine for Control of Postpartum Hypertension: A Randomized Controlled Trial

Lasix for the Prevention of De Novo Postpartum Hypertension

Fit After Baby: Increasing Postpartum Weight Loss in Women at Increased Risk for Cardiometabolic Disease

Prenatal Aspirin and Postpartum Vascular Function

Comprehensive Postpartum Management for Women With Hypertensive Disorders of Pregnancy

Vascular Effects of High-Salt After Preeclampsia

Postpartum Video Education

Wearables to Define Postpartum Blood Pressure Trajectories and Facilitate Evidence-based Monitoring Guidelines

Postpartum Management of Gestational Hypertensive Disorders Using Furosemide

Harvesting Health: Advancing Nutrition and Wellness for Moms and Babies

Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide

Gestational Changes in Hemodynamics and Respiratory Mechanics in Association With Pre-Eclampsia

A Randomized Feasibility Trial Comparing Drospirenone and Norethindrone for Postpartum Hypertension Management in Preeclampsia

Optimal Blood Pressure Treatment Thresholds Postpartum

Assessment of Postpartum Education to Improve Compliance

Nudge to Drive Transitions of Care

Balance of Angiotensin II Receptors in Vessel Function After Preeclampsia