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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Post Traumatic Headache Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

The Effects of a Specific Exercise Program on Subjects With Cervicogenic Headache

NCT05500378
View directory record Official record
Conditions
Cervicogenic Headache
Interventions
Head extension and rotation movement
Other
Lead sponsor
Florida Gulf Coast University
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Fort Myers, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 20, 2026, 3:47 AM EDT
Completed Phase 2 Interventional

Hyperbaric Oxygen for Traumatic and Non-traumatic Brain Injury

NCT01986205
View directory record Official record
Conditions
Brain Injury, Chronic
Interventions
Hyperbaric Oxygen, Minimal pressure air
Combination Product
Lead sponsor
Lindell Weaver
Other
Eligibility
18 Years to 70 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 3, 2022 · Synced Sep 20, 2026, 3:47 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin

NCT02266329
View directory record Official record
Conditions
Posttraumatic Headache, Combat Disorders, Post Concussion Syndrome, Headache, Mild Traumatic Brain Injury, Posttraumatic Migraine
Interventions
prazosin hydrochloride, placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 20, 2026, 3:47 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study to Evaluate Biomarker Signature to Predict the Persistence of Post-traumatic Headache

NCT06132529
View directory record Official record
Conditions
Post-Traumatic Headache, Healthy
Interventions
Brain Magnetic Resonance Imaging (MRI) Scan, Speech Sample, Electronic Daily Headache Diary
Diagnostic Test · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
2
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Sep 20, 2026, 3:47 AM EDT
Completed Not applicable Interventional

Dry Needling for Cervicogenic Headache

NCT04305223
View directory record Official record
Conditions
Headache, Cervicogenic Headache
Interventions
Dry Needling, Upper extremity stretching program
Procedure · Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 18, 2020 · Synced Sep 20, 2026, 3:47 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Correlation Between Central Sensitization Inventory and Posturographic Data

NCT03058003
View directory record Official record
Conditions
Central Nervous System Sensitization
Interventions
Posturography Evaluation, Central Sensitization Inventory
Diagnostic Test · Other
Lead sponsor
Caps Research Network
Other
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 3, 2021 · Synced Sep 20, 2026, 3:47 AM EDT
Completed Phase 2 Interventional Results available

Amitriptyline to Prevent Headache After Traumatic Brain Injury

NCT01856270
View directory record Official record
Conditions
Brain Injuries, Post-Traumatic Headache
Interventions
Amitriptyline
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 20, 2026, 3:47 AM EDT
Terminated Not applicable Interventional

Acupuncture for Headache Post-Traumatic Brain Injury: A Feasibility Study

NCT04216173
View directory record Official record
Conditions
Post-Traumatic Headache, Traumatic Brain Injury
Interventions
Acupuncture
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 23, 2021 · Synced Sep 20, 2026, 3:47 AM EDT
Terminated Not applicable Interventional

Brain Biomarkers w/Mind-Body Tx in Veterans With Post Traumatic Headache (PTH)

NCT02145117
View directory record Official record
Conditions
Post Traumatic Headache
Interventions
MBSR
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 20, 2026, 3:47 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

NCT04806620
View directory record Official record
Conditions
Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA), Psoriatic Arthritis (PsA), Ankylosing Spondylitis (AS), Autoimmune Encephalitis, Celiac Disease, Celiac Disease in Children, Chronic Lyme Disease, Post-treatment Lyme Disease Syndrome, Crohn's Disease, Dysautonomia, Anorexia Nervosa, Bulimia Nervosa, ARFID, Avoidant / Restrictive Food Intake Disorder, Ehlers Danlos Syndrome, Endometriosis, Fibromyalgia (FM), Long COVID, Lupus, Migraines, Mast Cell Activation Syndrome, Multiple Sclerosis, Myalgic Encephalomyelitis (ME), Myasthenia Gravis, Generalized, Myasthenia Gravis in Children, Narcolepsy, Obsessive Compulsive Disorder (OCD), PANDAS, Pediatric Acute-onset Neuropsychiatric Syndrome (PANS), POTS - Postural Orthostatic Tachycardia Syndrome, General Anxiety Disorder, Social Anxiety Disorder, PTSD - Post Traumatic Stress Disorder, Psoriasis, Traumatic Brain Injury, Tourette's Syndrome, Inflammatory Bowel Disease (IBD), Autoimmune Diseases, Neurological Diseases or Conditions, Psychiatric Disorder, Sjogren's Syndrome, Ulcerative Colitis and Crohn's Disease
Interventions
Not listed
Lead sponsor
Brain Inflammation Collaborative
Other
Eligibility
2 Years and older
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Delafield, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 20, 2026, 3:47 AM EDT
Completed Phase 2 Interventional Results available

Sumatriptan as Treatment for Post-traumatic Headache

NCT01854385
View directory record Official record
Conditions
Post-traumatic Headache
Interventions
Sumatriptan 100 mg
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Sep 20, 2026, 3:47 AM EDT
Completed Not applicable Interventional Results available

Neurofeedback Impact on Veterans With mTBI

NCT04195685
View directory record Official record
Conditions
Concussion, mTBI, Post-Concussive Symptoms, Chronic Headache, Chronic Insomnia, Chronic Attention Disorder
Interventions
Neurofeedback (NFB)
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Sep 20, 2026, 3:47 AM EDT
Terminated Not applicable Interventional

Effectiveness of Dry Needling of the Sternocleidomastoid in Patients With Cervicogenic Headaches

NCT03730896
View directory record Official record
Conditions
Cervicogenic Headache
Interventions
Dry needling
Procedure
Lead sponsor
Florida Gulf Coast University
Other
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Hobart, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 22, 2020 · Synced Sep 20, 2026, 3:47 AM EDT
Recruiting Phase 1Phase 2 Interventional

Treating Chronic Cervicogenic Head and Neck Pain

NCT05617365
View directory record Official record
Conditions
Cervicogenic Headache, Neck Pain, Posterior
Interventions
Osteopathic Manipulative Therapy and Exercise Therapy
Combination Product
Lead sponsor
Michigan State University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 20, 2026, 3:47 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Active and Passive Cervical Flexion-rotation Tests

NCT02070172
View directory record Official record
Conditions
Cervicogenic Headaches
Interventions
Not listed
Lead sponsor
Des Moines University
Other
Eligibility
20 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 24, 2014 · Synced Sep 20, 2026, 3:47 AM EDT
Terminated Phase 3 Interventional Results available

A Prospective Controlled Treatment Trial for Post-Traumatic Headaches

NCT03007420
View directory record Official record
Conditions
Post-Traumatic Headaches
Interventions
Occipital Nerve Block (ONB) using lidocaine and dexamethosone, Cervical Medial Branch Block (CMBB) using lidocaine and dexamethosone
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 45 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 20, 2026, 3:47 AM EDT
Not listed Not applicable Interventional

Cervical-Cranial Dry Needling vs. Orthopedic Manual Therapy for Cervicogenic Headache

NCT03583190
View directory record Official record
Conditions
Cervicogenic Headache
Interventions
Cervical-cranial dry needling, Orthopedic manual therapy, Thoracic Manipulation, Exercise, Patient Education
Other
Lead sponsor
Youngstown State University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 20, 2026, 3:47 AM EDT
Active, not recruiting Not applicable Interventional

Mobile Subthreshold Exercise Program for Concussion--R01

NCT04688255
View directory record Official record
Conditions
Concussion, Brain, Concussion, Mild, Brain Injuries, Traumatic, Persistent Post Traumatic Headache, Post-Concussion Syndrome, Post-Concussive Syndrome, Chronic
Interventions
MSTEP, Stretching
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Sep 20, 2026, 3:47 AM EDT
Active, not recruiting Not applicable Interventional

The MONARCH Case Series Study: SPRINT® Peripheral Nerve Stimulation for the Treatment of Head Pain

NCT05491915
View directory record Official record
Conditions
Cervicogenic Headache, Occipital Neuralgia
Interventions
SPRINT Peripheral Nerve Stimulation (PNS) System
Device
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
10
States / cities
Santa Rosa, California • Waltham, Massachusetts • Rochester, Minnesota + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 20, 2026, 3:47 AM EDT
Completed Not applicable Interventional Results available

Acupuncture in Traumatic Brain Injury

NCT04369911
View directory record Official record
Conditions
Chronic Post-traumatic Headache, Mild Traumatic Brain Injury
Interventions
Acupuncture
Procedure
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 26, 2025 · Synced Sep 20, 2026, 3:47 AM EDT
Recruiting Phase 2 Interventional

Magnesium and Riboflavin Treatment for Post-Concussion Headache

NCT06260072
View directory record Official record
Conditions
Concussion, Intermediate
Interventions
magnesium and riboflavin supplement
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 40 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Sep 20, 2026, 3:47 AM EDT
Completed Not applicable Interventional

Manual Therapy and Exercise in Patients With Cervicogenic Headache

NCT01580280
View directory record Official record
Conditions
Cervicogenic Headache
Interventions
Thrust Manipulation, Non-thrust Mobilization and Exercise
Other
Lead sponsor
Alabama Physical Therapy & Acupuncture
Other
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Montgomery, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 13, 2014 · Synced Sep 20, 2026, 3:47 AM EDT
Terminated Phase 4 Interventional Results available

Treximet for Prevention of Post Traumatic Headache Associated With Cognitive Dysfunction

NCT01053507
View directory record Official record
Conditions
Post-Traumatic Headache
Interventions
sumatriptan/naproxen sodium, Placebo
Drug
Lead sponsor
Cady, Roger, M.D.
Individual
Eligibility
18 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
3
States / cities
Springfield, Missouri • Nashville, Tennessee • Temple, Texas
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Sep 20, 2026, 3:47 AM EDT
Completed Not applicable Interventional

e-CBT DTx for Post Traumatic Headaches in Adults With History of TBI

NCT06669780
View directory record Official record
Conditions
Post-Traumatic Headache
Interventions
AMMO PTH DTx, AMMO SHAM
Device
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Sep 20, 2026, 3:47 AM EDT