Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 7:46 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 1,847 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-Surgical Pain Clear all

Conditions: Pain
Interventions: EXPAREL, Bupivacaine; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years and older · Male only
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 17
States / cities: Fremont, California • Loma Linda, California • Fort Lauderdale, Florida + 13 more

Conditions: Pelvic Organ Prolapse, Postoperative Pain Management, Gynecologic Surgeries
Interventions: Sitz Bath; Device
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 112 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Autonomic Nerve Block
Interventions: Pecto-intercostal Fascial Block with 20 ml of 0.35% ropivacaine, Pecto-intercostal Fascial Block with normal saline; Procedure
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2029
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Pain, Postoperative, Opioid Misuse, Opioid Use, Pain
Interventions: OxyCODONE 5 mg Oral Tablet, Acetaminophen 500 mg Tab, Ibuprofen 600 mg; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Post op Pain
Interventions: questionnaires; Other
Lead sponsor: East Carolina University; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Greenville, North Carolina

Conditions: Injury; Nerve, Peripheral, Multiple, Chronic Post-Procedural Pain, Total Knee Arthroplasty, Surgery, Knee Injuries, Knee Pain Chronic, Postoperative Pain, Chronic Postoperative Pain
Interventions: SPRINT® Peripheral Nerve Stimulation (PNS) System (510k Cleared); Device
Lead sponsor: Stanford University; Other
Eligibility: 21 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Pain, Postoperative
Interventions: Exparel, Interscalene Nerve Block; Drug · Procedure
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Pain, Postoperative
Interventions: Twin block, iPill dispenser; Drug · Device
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years and older
Enrollment: 133 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Post-Operative Pain Management
Interventions: ioveraº, ioveraº sham; Device
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 22 Years and older
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 7
States / cities: Fremont, California • Pasadena, California • Tamarac, Florida + 4 more

Conditions: Distal Radius Fracture, Radius Fracture Distal, Radius; Fracture, Lower or Distal End, Postoperative Pain
Interventions: Vibration tool; Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Adenotonsillar Hypertrophy, Obstructive Sleep Apnea, Sleep-Disordered Breathing, Acute Post Operative Pain
Interventions: Ketorolac; Drug
Lead sponsor: St. Louis University; Other
Eligibility: 3 Years to 12 Years
Enrollment: 142 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Pain
Interventions: Exparel, Indwelling Interscalene Catheter; Drug · Device
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 40 Years to 74 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Post-operative Pain
Interventions: Multimodal Pain Management (Ibuprofen/Acetaminophen/GABAPentin/0.25%Bupivacaine); Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: San Diego, California

Conditions: Breast Cancer, Chronic Pain
Interventions: No intervention; Other
Lead sponsor: University of Florida; Other
Eligibility: 40 Years to 75 Years · Female only
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Postoperative Pain Management
Interventions: Dexmedetomidine, Ropivacaine; Drug
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 18 Years to 80 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Post Surgical Ocular Inflammation
Interventions: TRS01 eye drops, Placebo eye drops; Drug
Lead sponsor: Tarsier Pharma; Industry
Eligibility: 18 Years and older
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 5
States / cities: Inglewood, California • Petaluma, California • Washington, Missouri + 2 more

Conditions: Dental Pain and Sensation Disorder, Pain, Postoperative
Interventions: Gabapentin 600mg, Placebo; Drug
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years to 59 Years
Enrollment: 98 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Postoperative Pain
Interventions: Fentanyl, Ketorolac, Nerve of Arnold Block, Sham Intramuscular Injection, Sham Nerve of Arnold Block, Dexmedetomidine, Bupivacaine; Drug · Procedure
Lead sponsor: University of South Alabama; Other
Eligibility: 6 Months to 6 Years
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Mobile, Alabama

Conditions: Hand Injury, Wrist Injury, Finger Injury
Interventions: 0.5% bupivacaine injected in the forearm, 20-30ml of 0.5% bupivacaine.; Procedure
Lead sponsor: Jose Soberon, MD; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Complex Obstetric Surgery, Perioperative Pain Management, Cesarean Delivery, Postoperative Pain Control
Interventions: Bupivicaine intervention arm, Placebo arm; Drug
Lead sponsor: University of Tennessee; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Postoperative Pain, Acute, Shoulder Pain
Interventions: intercostobrachial nerve block; Procedure
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Elective Spine Surgery Receiving Pre and/or Postoperative Pain Control With Opioids
Interventions: Opioid and Benzodiazepine Naive-patients, Opioid and Benzodiazepine Tolerant-patients; Behavioral
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 21 Years to 75 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Total Hip Arthroplasty
Interventions: L2 Paravertebral catheter nerve block, Continuous Lumbar plexus nerve block; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Postmastectomy Lymphedema Syndrome, Pain, Shoulder Mobility Impairment, Breast Surgery
Interventions: Myofascial Massage Therapy, Global Relaxation Massage; Other
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 21 Years to 79 Years · Female only
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Cleveland, Ohio

Search by objective public record fields.

Local Infiltration Analgesia With and Without EXPAREL Following Total Knee Arthroplasty

SORE Study: Sitz Baths After Urogynecologic Reconstruction

Sternotomy PIFB Block in Open Heart Surgery

Reduced Opioid Prescription After Laparoscopic Hysterectomy

Phenotyping Acute Pain for Discovery Research and Directed Therapeutics

Using Peripheral Nerve Stimulation (PNS) to Treat Chronic Post-surgical Pain (CPSP) After Knee Surgery

Liposomal Bupivacaine Versus Interscalene Nerve Block

Reducing Opioid Use and Misuse After Wisdom Molar Extractions

Study to Evaluate Iovera®° in Adult Patients Undergoing Total Knee Arthroplasty

Use of a Vibration Tool for Postoperative Pain Control in Distal Radius Fractures

Ketorolac on Postoperative Pain Reduction in Pediatric Patients with Adenotonsillectomy

Exparel Interscalene vs Indwelling Catheter

Comparing Perioperative Outcomes in Pain Control

Persistent Post-Surgical Pain in Women With BrCA

Suprainguinal Fascia Iliaca Block With vs Without Dexmedetomidine

A Study of TRS01 in Participants With Post-surgical Ocular Inflammation

Efficacy of Preoperative Administration of Gabapentin in 3rd Molar Dental Extraction.

Comparing Intramuscular Fentanyl and Ketorolac With Nerve of Arnold (NOA) Block for Bilateral Myringotomy

Comparing Two Injection Sites of Local Anesthetic for Hand Surgery

COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block

Evaluating Intercostobrachial Nerve Block's Effect on Pain Control After Shoulder Replacement

Impact of Daily, Digital and Behavioral Tele-health Tapering Program for Perioperative Surgical Patients Exposed to Opioids and Benzodiazepines.

Continuous L2 Paravertebral Block Versus Continuous Lumbar Plexus Block for Postoperative Analgesia

Massage for Post Breast Surgery