Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:36 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 1,847 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Post-Surgical Pain Clear all

Conditions: Post Operative Pain
Interventions: Continuous Infusion of ropivacaine, Intermittent bolus of ropivacaine; Drug
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years to 90 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Phantom Limb Pain
Interventions: Graded motor imagery mobile app; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 89 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Pain, Postoperative
Interventions: XaraColl, Placebo; Drug · Other
Lead sponsor: Innocoll; Industry
Eligibility: 18 Years and older
Enrollment: 319 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 24
States / cities: Anniston, Alabama • Birmingham, Alabama • Anaheim, California + 19 more

Conditions: Postoperative Pain
Interventions: SKY0402, Bupivacaine HCl; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 4
States / cities: San Clemente, California • Miami, Florida • Houston, Texas + 1 more

Conditions: Postoperative Pain
Interventions: Percutaneous peripheral nerve stimulation, Sham stimulation; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 3
States / cities: La Jolla, California • San Diego, California

Conditions: Amputation, Chronic Pain
Interventions: morphine and mexiletine; Drug
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 18 Years to 85 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1997 – 2003
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Pulmonary Dysfunction, Median Sternotomy Recovery, Postoperative Pain
Interventions: Intercostal Nerve Cryoablation; Device
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 40 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Cesarean Section Complications, Pain, Opioid Use
Interventions: Liposomal bupivacaine, Bupivacaine Hydrochloride, saline; Drug · Other
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis
Interventions: Alternating Acetaminophen and Ibuprofen, Combined Acetaminophen and Ibuprofen; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 4 Years to 17 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Cataract
Interventions: Nepafenac Ophthalmic Suspension, 0.3%, Nepafenac Ophthalmic Suspension, 0.1%, Nepafenac Ophthalmic Suspension 0.3% Vehicle, NEVANAC Vehicle; Drug · Other
Lead sponsor: Alcon Research; Industry
Eligibility: 18 Years and older
Enrollment: 2,120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2010
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Postoperative Pain, Acute, Opioid Use, Labral Tear, Glenoid
Interventions: Tylenol, Ibuprofen, and Oxycodone, Tylenol and Ibuprofen only; Drug
Lead sponsor: Cooper Norcross Health; Other
Eligibility: 15 Years to 25 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Camden, New Jersey

Conditions: Postoperative Pain
Interventions: root canal treatment, anesthesia, pain medications, and antibiotic, no root canal treatment, anesthesia, pain medications, and antibiotic; Procedure
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Anesthesia, Urethral Obstruction
Interventions: Placebo, Gabapentin; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Bunions, Postoperative Pain
Interventions: HTX-034 low dose, HTX-034 high dose, Luer lock applicator, Bupivacaine HCl; Drug · Device
Lead sponsor: Heron Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 4
States / cities: Phoenix, Arizona • Bellaire, Texas • San Antonio, Texas + 1 more

Conditions: Postoperative Pain, Pelvic Organ Prolapse, Trigger Point Injection, Sacrospinous Ligament Fixation
Interventions: marcaine and kenalog; Drug
Lead sponsor: Kettering Health Network; Other
Eligibility: 21 Years and older · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Dayton, Ohio

Conditions: Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
Interventions: Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail, Placebo; Drug · Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 88 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Acute Pain
Interventions: Oxymorphone immediate release; Drug
Lead sponsor: Endo USA Inc., a Keenova Therapeutics Company; Industry
Eligibility: 18 Years and older
Enrollment: 320 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2005
U.S. locations: 21
States / cities: Birmingham, Alabama • Montgomery, Alabama • Phoenix, Arizona + 10 more

Conditions: Postoperative Pain, Nausea, Vomiting, Anxiety, Depression
Interventions: Acupuncture; Procedure
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 238 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Post-operation Pain
Interventions: MDT-10013; Drug
Lead sponsor: Medtronic Spinal and Biologics; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 3
States / cities: Birmingham, Alabama • DeLand, Florida • Altoona, Pennsylvania

Conditions: Acute Moderate-to-severe Pain
Interventions: sufentanil sublingual tablet 30 mcg; Drug
Lead sponsor: Talphera, Inc; Industry
Eligibility: 40 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 2
States / cities: Houston, Texas

Conditions: Osteoarthritis (OA) of the Knee
Interventions: oral suzetrigine, oral Oxycodone; Drug
Lead sponsor: University of Louisville; Other
Eligibility: 21 Years to 89 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Femoro Acetabular Impingement, Pain, Postoperative
Interventions: Warmed Arthroscopic Fluids, Room Temperature Arthroscopic Fluids; Procedure
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 65 Years
Enrollment: 11 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Englewood, Colorado

Conditions: Pain, Postoperative
Interventions: No specific treatment based intervention-health measurement instrument; Other
Lead sponsor: Defense and Veterans Center for Integrative Pain Management; Other
Eligibility: 18 Years to 80 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Postoperative Pain
Interventions: Acetaminophen Oral Tablet, placebo oral tablet, Acetaminophen infusion, Placebo infusion; Drug
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Stanford, California

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Intermittent Bolus vs Continuous Infusion Via ESP Catheters RCT

Home-based Rehabilitation Intervention for Phantom Limb Pain in Veterans With Lower Limb Amputations

Phase 3 Study of Efficacy and Safety of the XaraColl® Bupivacaine Implant After Hernioplasty

Phase 2 Dose-Ranging Study of SKY0402 for Prolonged Postoperative Analgesia in Subject Undergoing Hemorrhoidectomy

Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Analgesia

Efficacy of Opioids and Mexiletine for the Treatment of Postamputation Pain

FROST-STERN Trial: A Trial of Intraoperative Cryoablation for Post Operative Pain Management After Full Sternotomy

Obstetric Liposomal Bupivacaine Via Surgical Transversus Abdominis Plane Block for Post Cesarean Pain Control

Management of Post-Tonsillectomy Pain in Pediatric Patients

Confirmatory Study Nepafenac 0.3%

Randomized Trial of Narcotic vs Non-Narcotic Pain Modulation After Labrum Repair

Effect of Root Canal Treatment (Versus no Treatment) for Patients With Tooth Infections and Toothaches

Gabapentin on Postoperative Pain Associated With Ureteroscopy and Stents Insertion

Dose-Escalation Study of HTX-034 Following Bunionectomy

The Effect of Local Analgesia on Postoperative Gluteal Pain in Patients Undergoing Sacrospinous Ligament Fixation

Effect of RECK in Posterior Spinal Fusion

Efficacy and Safety of Oxymorphone Immediate Release in Post-surgical Acute Pain

Pragmatic Research eXamining Inpatient Symptoms

A Feasibility Dose-escalating Study of MDT-10013 for Acute Postoperative Pain Following Total Knee Arthroplasty

A Multicenter, Open-Label Trial to Evaluate the Safety and Efficacy of the Sufentanil Sublingual Tablet 30 mcg in Patients With Post-Operative Pain

Comparison of Suzetrigine and Oxycodone for Postoperative Pain After Primary Total Knee Arthroplasty

Effect of Warmed Irrigation in Hip Arthroscopy Undergoing Hip Arthroscopy

Biopsychosocial Impact on Caregivers in Patients Undergoing Joint and Spine Surgery

Oral Versus Intravenous Acetaminophen in Lumbar Spine Surgery